Search Results - "Guo, Chuang"
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Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution
Published in Nature methods (01-06-2022)“…Spatial transcriptomics approaches have substantially advanced our capacity to detect the spatial distribution of RNA transcripts in tissues, yet it remains…”
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Iron and Alzheimer's Disease: From Pathogenesis to Therapeutic Implications
Published in Frontiers in neuroscience (10-09-2018)“…As people age, iron deposits in different areas of the brain may impair normal cognitive function and behavior. Abnormal iron metabolism generates hydroxyl…”
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The Interrelationships between Cytokines and Schizophrenia: A Systematic Review
Published in International journal of molecular sciences (01-08-2024)“…Schizophrenia (SCZ) imposes a significant burden on patients and their families because of its high prevalence rate and disabling nature. Given the lack of…”
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A Review on Lactoferrin and Central Nervous System Diseases
Published in Cells (Basel, Switzerland) (17-07-2021)“…Central nervous system (CNS) diseases are currently one of the major health issues around the world. Most CNS disorders are characterized by high oxidative…”
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Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm
Published in Nature communications (06-08-2020)“…Several studies show that the immunosuppressive drugs targeting the interleukin-6 (IL-6) receptor, including tocilizumab, ameliorate lethal inflammatory…”
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The emerging roles of microbiota-derived extracellular vesicles in psychiatric disorders
Published in Frontiers in microbiology (08-04-2024)“…Major depressive disorder, schizophrenia, and bipolar disorder are three major psychiatric disorders that significantly impact the well-being and overall…”
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Long-term corrosion behavior of the 7A85 aluminum alloy in an industrial-marine atmospheric environment
Published in Journal of materials research and technology (01-05-2021)“…The atmospheric corrosion behavior and mechanism of the 7A85 aluminum alloy exposed to the Qingdao industrial-marine atmospheric environment for five years was…”
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Comparison of continuous pericapsular nerve group (PENG) block versus continuous fascia iliaca compartment block on pain management and quadriceps muscle strength after total hip arthroplasty: a prospective, randomized controlled study
Published in BMC anesthesiology (11-07-2023)“…This investigation aimed to evaluate the impact of continuous pericapsular nerve group (PENG) block and continuous fascia iliac compartment block (FICB) on…”
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Competitive adsorption of dye metanil yellow and RB15 in acid solutions on chemically cross-linked chitosan beads
Published in Chemosphere (Oxford) (01-02-2006)“…One kind of adsorbent with a high adsorption capacity for anionic dyes was prepared using ionically and chemically cross-linked chitosan beads. A batch system…”
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MiRNAs of peripheral blood as the biomarker of schizophrenia
Published in Hereditas (29-08-2017)“…The diagnosis of schizophrenia is currently based on the symptoms and bodily signs rather than on the pathological and physiological markers of the patient. In…”
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The Role of microRNA in Schizophrenia: A Scoping Review
Published in International journal of molecular sciences (01-07-2024)“…Schizophrenia is a serious mental disease that is regulated by multiple genes and influenced by multiple factors. Due to the complexity of its etiology, the…”
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12
Activated spinal astrocytes contribute to the later phase of carrageenan-induced prostatitis pain
Published in Journal of neuroinflammation (25-10-2019)“…Prostatodynia is the main symptom of chronic prostatitis and the main reason that patients go to the hospital for treatment. Although a variety of factors,…”
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Effects of Fe content on microstructure and properties of Cu–Fe alloy
Published in Transactions of Nonferrous Metals Society of China (01-10-2021)“…Cu–Fe alloys with different Fe contents were prepared by vacuum hot pressing. After hot rolling and aging treatment, the effects of Fe content on…”
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14
Classification for Penicillium expansum Spoilage and Defect in Apples by Electronic Nose Combined with Chemometrics
Published in Sensors (Basel, Switzerland) (09-04-2020)“…It is crucial for the efficacy of the apple storage to apply methods like electronic nose systems for detection and prediction of spoilage or infection by …”
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Lactoferrin ameliorates dopaminergic neurodegeneration and motor deficits in MPTP-treated mice
Published in Redox biology (01-02-2019)“…Brain iron accumulation is common in patients with Parkinson's disease (PD). Iron chelators have been investigated for their ability to prevent…”
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Comparative analysis of methodologies for detecting extrachromosomal circular DNA
Published in Nature communications (25-10-2024)“…Extrachromosomal circular DNA (eccDNA) is crucial in oncogene amplification, gene transcription regulation, and intratumor heterogeneity. While various…”
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A comprehensive analysis of the role of cuproptosis in periodontitis through integrated analysis of single-cell and bulk RNA sequencing
Published in Archives of medical science (2024)“…Trace mineral micronutrients are essential for periodontal health, and unbalanced levels of trace minerals are related to chronic periodontitis, including…”
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Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes
Published in Cell reports (Cambridge) (05-10-2021)“…The mortality risk of coronavirus disease 2019 (COVID-19) patients has been linked to the cytokine storm caused by severe acute respiratory syndrome…”
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A Novel Cu(II)-Binding Peptide Identified by Phage Display Inhibits Cu2+-Mediated Aβ Aggregation
Published in International journal of molecular sciences (25-06-2021)“…Copper (Cu) has been implicated in the progression of Alzheimer’s disease (AD), and aggregation of Cu and amyloid β peptide (Aβ) are considered key…”
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Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain
Published in Neurochemistry international (01-01-2013)“…► Fe treatment induced tau phosphorylation at Thr205, Thr231and Ser396 sites. ► The iron chelator, desferrioxamine (DFO), reduces Fe induced tau…”
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