Search Results - "Guo, Chang"

MiRNA-Mediated Macrophage Polarization and its Potential Role in the Regulation of Inflammatory Response by Essandoh, Kobina, Li, Yutian, Huo, Jiuzhou, Fan, Guo-Chang

“…ABSTRACTMonocytes and macrophages are important components of the immune system, specialized in either removing pathogens as part of innate immunity or…”
Get full text

Asymmetric Electrochemical Transformations by Chang, Xihao, Zhang, Qinglin, Guo, Chang

“…The field of electrochemical synthesis has developed rapidly over the last decade and has provided alternative synthetic methods with the absence of…”
Get full text

Sea buckthorn (Hippophae rhamnoides L.) fermentation liquid protects against alcoholic liver disease linked to regulation of liver metabolome and the abundance of gut microbiota by Ran, Beibei, Guo, Chang‐E, Li, Weidong, Li, Weishi, Wang, Qing, Qian, Jinxiu, Li, Hailong

“…BACKGROUND Alcoholic liver disease (ALD) refers to liver damage caused by long‐term heavy drinking, which causes oxidative stress and changes in gut…”
Get full text

A Review of Multi-Agent Game in Intellectual Property Pledge Financing by Guo, Chang

“…To promote the theoretical research and business development of intellectual property pledge financing, this paper summarizes the research status of…”
Get full text

Prevalence and socio-demographic correlates of psychological health problems in Chinese adolescents during the outbreak of COVID-19 by Zhou, Shuang-Jiang, Zhang, Li-Gang, Wang, Lei-Lei, Guo, Zhao-Chang, Wang, Jing-Qi, Chen, Jin-Cheng, Liu, Mei, Chen, Xi, Chen, Jing-Xu

“…Psychological health problems, especially emotional disorders, are common among adolescents. The epidemiology of emotional disorders is greatly influenced by…”
Get full text

Role of extracellular and intracellular microRNAs in sepsis by Essandoh, Kobina, Fan, Guo-Chang

“…Sepsis is the major cause of death in the intensive care unit (ICU). Numerous biomarkers have been studied to identify the cause and severity of sepsis but…”
Get full text

Pathologic function and therapeutic potential of exosomes in cardiovascular disease by Ailawadi, Shaina, Wang, Xiaohong, Gu, Haitao, Fan, Guo-Chang

“…The heart is a very complex conglomeration of organized interactions between various different cell types that all aid in facilitating myocardial function…”
Get full text

Tissue-Resident Macrophages in the Control of Infection and Resolution of Inflammation by Mu, Xingjiang, Li, Yutian, Fan, Guo-Chang

“…ABSTRACTMacrophage, as an integral component of the immune system and the first responder to local damage, is on the front line of defense against infection…”
Get full text

Enantioselective Synthesis of Atropisomeric Biaryls by Pd‐Catalyzed Asymmetric Buchwald–Hartwig Amination by Zhang, Peng, Wang, Xiao‐Mei, Xu, Qi, Guo, Chang‐Qiu, Wang, Peng, Lu, Chuan‐Jun, Liu, Ren‐Rong

“…N−C Biaryl atropisomers are prevalent in natural products and bioactive drug molecules. However, the enantioselective synthesis of such molecules has not…”
Get full text

Asymmetric Lewis Acid Catalyzed Electrochemical Alkylation by Zhang, Qinglin, Chang, Xihao, Peng, Lingzi, Guo, Chang

“…Lewis‐acid catalysis and electrochemistry represent two powerful fields that have found widespread application in organic chemistry. Reported herein is an…”
Get full text

Underwater Image Enhancement by Dehazing With Minimum Information Loss and Histogram Distribution Prior by Li, Chong-Yi, Guo, Ji-Chang, Cong, Run-Min, Pang, Yan-Wei, Wang, Bo

“…Images captured under water are usually degraded due to the effects of absorption and scattering. Degraded underwater images show some limitations when they…”
Get full text

Improved Prediction of Blood–Brain Barrier Permeability Through Machine Learning with Combined Use of Molecular Property-Based Descriptors and Fingerprints by Yuan, Yaxia, Zheng, Fang, Zhan, Chang-Guo

“…Blood–brain barrier (BBB) permeability of a compound determines whether the compound can effectively enter the brain. It is an essential property which must be…”
Get full text

Cooperative Ni/Cu‐Catalyzed Asymmetric Propargylic Alkylation of Aldimine Esters by Peng, Lingzi, He, Zhuozhuo, Xu, Xianghong, Guo, Chang

“…A novel Ni/Cu dual catalysis gives rise to fundamentally new cooperative reactivity and enables the regio‐ and enantioselective propargylic alkylation…”
Get full text

Administration of nicotinamide riboside prevents oxidative stress and organ injury in sepsis by Hong, Guangliang, Zheng, Dong, Zhang, Lulu, Ni, Rui, Wang, Grace, Fan, Guo-Chang, Lu, Zhongqiu, Peng, Tianqing

“…Sepsis-caused multiple organ failure remains the major cause of morbidity and mortality in intensive care units. Nicotinamide riboside (NR) is a precursor of…”
Get full text

Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs by Li, Zhe, Li, Xin, Huang, Yi-You, Wu, Yaoxing, Liu, Runduo, Zhou, Lingli, Lin, Yuxi, Wu, Deyan, Zhang, Lei, Liu, Hao, Xu, Ximing, Yu, Kunqian, Zhang, Yuxia, Cui, Jun, Zhan, Chang-Guo, Wang, Xin, Luo, Hai-Bin

“…The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global crisis. There is no therapeutic treatment…”
Get full text

Hypoxic exosomes promote angiogenesis by Fan, Guo-Chang

“…In this issue of Blood, Umezu et al identified that exosomal miR-135b plays a critical role in mediating multiple myeloma (MM) cell-to-endothelial cell…”
Get full text

Association of PD‐L1 expression status with the efficacy of PD‐1/PD‐L1 inhibitors and overall survival in solid tumours: A systematic review and meta‐analysis by Liu, Xi, Guo, Chang‐Ying, Tou, Fang‐Fang, Wen, Xiao‐Ming, Kuang, Yu‐Kang, Zhu, Qian, Hu, Hao

“…Whether PD‐L1‐positive patients derive more overall survival benefit from PD‐1/PD‐L1 inhibitors in the treatment of advanced solid tumours is unclear. We…”
Get full text

Versatile effects of bacterium-released membrane vesicles on mammalian cells and infectious/inflammatory diseases by Yu, You-jiang, Wang, Xiao-hong, Fan, Guo-Chang

“…Gram-negative bacterium-released outer-membrane vesicles (OMVs) and Gram-positive bacterium-released membrane vesicles (MVs) share significant similarities…”
Get full text

Merging Electrosynthesis and Bifunctional Squaramide Catalysis in the Asymmetric Detrifluoroacetylative Alkylation Reactions by Chang, Xihao, Zhang, Jiayin, Zhang, Qinglin, Guo, Chang

“…An enantioselective bifunctional squaramide‐catalyzed detrifluoroacetylative alkylation reaction has been developed under electrochemical conditions. The…”
Get full text

The Effect of Social Support on Mental Health in Chinese Adolescents During the Outbreak of COVID-19 by Qi, Meng, Zhou, Shuang-Jiang, Guo, Zhao-Chang, Zhang, Li-Gang, Min, Hong-Jie, Li, Xiao-Min, Chen, Jing-Xu

“…The coronavirus disease 2019 (COVID-19) outbreak impacts physical and mental health. The purpose of this study was to explore the association between the…”
Get full text