Search Results - "Guo, Ang"
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Confinement of Ionic Liquids in Nanocages: Tailoring the Molecular Sieving Properties of ZIF-8 for Membrane-Based CO2 Capture
Published in Angewandte Chemie International Edition (14-12-2015)“…Fine‐tuning of effective pore size of microporous materials is necessary to achieve precise molecular sieving properties. Herein, we demonstrate that room…”
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Sequence determinants of human junctophilin-2 protein nuclear localization and phase separation
Published in Biochemical and biophysical research communications (23-07-2021)“…Junctophilin-2 (JPH2) was conventionally considered as a structural membrane binding protein. Recently, it was shown that proteolytically truncated mouse JPH2…”
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Road Weather Condition Recognition via Fusing Images and Upsampled Point Cloud Reflection Intensities
Published in IEEE sensors journal (15-06-2024)“…The recognition of road weather conditions can provide environmental information for autonomous driving systems, enabling them to develop safe driving…”
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Chemically Cross-Linked MOF Membrane Generated from Imidazolium-Based Ionic Liquid-Decorated UiO-66 Type NMOF and Its Application toward CO2 Separation and Conversion
Published in ACS applied materials & interfaces (08-11-2017)“…Carbon dioxide capture and transformation are of great importance to make cuts in greenhouse gas emissions. Nanometal–organic frameworks (NMOFs) could serve as…”
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T-Tubule Remodeling During Transition From Hypertrophy to Heart Failure
Published in Circulation research (20-08-2010)“…RATIONALE:The transverse tubule (T-tubule) system is the ultrastructural substrate for excitation–contraction coupling in ventricular myocytes; T-tubule…”
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Analysis of Cardiac Myocyte Maturation Using CASAAV, a Platform for Rapid Dissection of Cardiac Myocyte Gene Function In Vivo
Published in Circulation research (09-06-2017)“…RATIONALE:Loss-of-function studies in cardiac myocytes (CMs) are currently limited by the need for appropriate conditional knockout alleles. The factors that…”
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Carbon molecular sieving membranes for butane isomer separation
Published in AIChE journal (01-11-2019)“…Membrane‐based separations of hydrocarbon isomers are major challenges for the petrochemical industry. Herein, high quality carbon molecular sieving membranes…”
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E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator
Published in Science (American Association for the Advancement of Science) (21-12-2018)“…Junctophilin-2 (JP2) is a structural protein required for normal excitation-contraction (E-C) coupling. After cardiac stress, JP2 is cleaved by the calcium…”
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The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias
Published in Nature medicine (01-02-2014)“…In heart muscle cells, sarcoplasmic reticulum calcium overload leads to spontaneous calcium waves that can cause arrhythmias and sudden cardiac death. S.R…”
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Microtubule-Mediated Defects in Junctophilin-2 Trafficking Contribute to Myocyte Transverse-Tubule Remodeling and Ca2+ Handling Dysfunction in Heart Failure
Published in Circulation (New York, N.Y.) (29-04-2014)“…BACKGROUND—Cardiac dysfunction in failing hearts of human patients and animal models is associated with both microtubule densification and transverse-tubule…”
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Overexpression of junctophilin-2 does not enhance baseline function but attenuates heart failure development after cardiac stress
Published in Proceedings of the National Academy of Sciences - PNAS (19-08-2014)“…Heart failure is accompanied by a loss of the orderly disposition of transverse (T)-tubules and a decrease of their associations with the junctional…”
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Molecular Determinants of Calpain-dependent Cleavage of Junctophilin-2 Protein in Cardiomyocytes
Published in The Journal of biological chemistry (17-07-2015)“…Junctophilin-2 (JP2), a membrane-binding protein that provides a structural bridge between the plasmalemma and sarcoplasmic reticulum, is essential for precise…”
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Carvedilol and its new analogs suppress arrhythmogenic store overload–induced Ca2+ release
Published in Nature medicine (10-07-2011)“…The widely prescribed beta blocker carvedilol has strong antiarrhythmic effects on the heart, but the underlying mechanisms have been unclear. Qiang Zhou et al…”
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End-to-End Joint Multi-Object Detection and Tracking for Intelligent Transportation Systems
Published in Chinese journal of mechanical engineering (20-11-2023)“…Environment perception is one of the most critical technology of intelligent transportation systems (ITS). Motion interaction between multiple vehicles in ITS…”
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Deinococcus detaillensis sp. nov., isolated from humus soil in Antarctica
Published in Archives of microbiology (01-11-2020)“…A Gram-staining-positive, non-motile, coccus or short-rod-shaped bacterium, designated H1 T , was isolated from a humus soil sample in the Detaille Island of…”
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Sildenafil Prevents and Reverses Transverse-Tubule Remodeling and Ca2+ Handling Dysfunction in Right Ventricle Failure Induced by Pulmonary Artery Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-02-2012)“…Right ventricular (RV) failure (RVF) is the main cause of death in patients with pulmonary artery hypertension (PAH). Sildenafil, a phosphodiesterase type 5…”
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Calsequestrin Accumulation in Rough Endoplasmic Reticulum Promotes Perinuclear Ca2+ Release
Published in The Journal of biological chemistry (11-05-2012)“…Molecular mechanisms underlying Ca2+ regulation by perinuclear endoplasmic/sarcoplasmic reticulum (ER/SR) cisternae in cardiomyocytes remain obscure. To…”
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Phospholamban Knockout Breaks Arrhythmogenic Ca2+ Waves and Suppresses Catecholaminergic Polymorphic Ventricular Tachycardia in Mice
Published in Circulation research (16-08-2013)“…RATIONALE:Phospholamban (PLN) is an inhibitor of cardiac sarco(endo)plasmic reticulum Ca ATPase. PLN knockout (PLN-KO) enhances sarcoplasmic reticulum Ca load…”
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SOmicsFusion: Multimodal coregistration and fusion between spatial metabolomics and biomedical imaging
Published in Artificial intelligence chemistry (01-06-2024)“…We present SOmicsFusion, a software toolbox for ’fusing’ spatial omics with classical biomedical imaging modalities, capitalizing on their inherent…”
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