Search Results - "Gunter, Barak W."

Acyloxy nitroso compounds inhibit LIF signaling in endothelial cells and cardiac myocytes: evidence that STAT3 signaling is redox-sensitive by Zgheib, Carlos, Kurdi, Mazen, Zouein, Fouad A, Gunter, Barak W, Stanley, Brian A, Zgheib, Joe, Romero, Damian G, King, S Bruce, Paolocci, Nazareno, Booz, George W

“…We previously showed that oxidative stress inhibits leukemia inhibitory factor (LIF) signaling by targeting JAK1, and the catalytic domains of JAK 1 and 2 have…”
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Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M4 PAM VU0467154 by Gould, Robert W., Grannan, Michael D., Gunter, Barak W., Ball, Jacob, Bubser, Michael, Bridges, Thomas M., Wess, Jurgen, Wood, Michael W., Brandon, Nicholas J., Duggan, Mark E., Niswender, Colleen M., Lindsley, Craig W., Conn, P. Jeffrey, Jones, Carrie K.

“…Although selective activation of the M1 muscarinic acetylcholine receptor (mAChR) subtype has been shown to improve cognitive function in animal models of…”
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Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M 4 PAM VU0467154 by Gould, Robert W, Grannan, Michael D, Gunter, Barak W, Ball, Jacob, Bubser, Michael, Bridges, Thomas M, Wess, Jurgen, Wood, Michael W, Brandon, Nicholas J, Duggan, Mark E, Niswender, Colleen M, Lindsley, Craig W, Conn, P Jeffrey, Jones, Carrie K

“…Although selective activation of the M muscarinic acetylcholine receptor (mAChR) subtype has been shown to improve cognitive function in animal models of…”
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Attenuation of social interaction-associated ultrasonic vocalizations and spatial working memory performance in rats exposed to chronic unpredictable stress by Riaz, Muhammad S, Bohlen, Martin O, Gunter, Barak W, Henry, Quentin, Stockmeier, Craig A, Paul, Ian A

“…Abstract Exposure to unpredictable chronic mild stress (CUS) is a commonly used protocol in rats that is reported to evoke antidepressant-reversible behaviors…”
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Selective inhibition of M 5 muscarinic acetylcholine receptors attenuates cocaine self-administration in rats by Gunter, Barak W, Gould, Robert W, Bubser, Michael, McGowan, Kevin M, Lindsley, Craig W, Jones, Carrie K

“…Cocaine use disorder (CUD) remains a debilitating health problem in the United States for which there are no Food and Drug Administration-approved treatment…”
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Acute Negative Allosteric Modulation of M5 Muscarinic Acetylcholine Receptors Inhibits Oxycodone Self-Administration and Cue-Induced Reactivity with No Effect on Antinociception by Gould, Robert W, Gunter, Barak W, Bubser, Michael, Matthews, Robert T, Teal, Laura B, Ragland, Madeline G, Bridges, Thomas M, Garrison, Aaron T, Winder, Danny G, Lindsley, Craig W, Jones, Carrie K

“…Opioid use disorder (OUD) is a debilitating neuropsychiatric condition characterized by compulsive opioid use, dependence, and repeated relapse after periods…”
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Acute Negative Allosteric Modulation of M 5 Muscarinic Acetylcholine Receptors Inhibits Oxycodone Self-Administration and Cue-Induced Reactivity with No Effect on Antinociception by Gould, Robert W, Gunter, Barak W, Bubser, Michael, Matthews, Robert T, Teal, Laura B, Ragland, Madeline G, Bridges, Thomas M, Garrison, Aaron T, Winder, Danny G, Lindsley, Craig W, Jones, Carrie K

“…Opioid use disorder (OUD) is a debilitating neuropsychiatric condition characterized by compulsive opioid use, dependence, and repeated relapse after periods…”
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Anxiolytic-like and discriminative stimulus effects of benzodiazepine + neuroactive steroid combinations in rats by Gunter, Barak W, Jones, Sherman A, Platt, Donna, Rowlett, James K

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Reinstatement of drug-seeking behavior in rats trained to self-administer intravenous injections of midazolam by Gunter, Barak W, Platt, Donna, Rueedi-bettschen, Daniela, Freeman, Kevin, Rowlett, James

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Differential interactions engendered by benzodiazepine and neuroactive steroid combinations on schedule-controlled responding in rats by Gunter, Barak W., Platt, Donna M., Rowlett, James K.

“…Benzodiazepines are positive allosteric modulators of the GABAA receptor and are prescribed as anxiolytics, hypnotics, and anticonvulsants. While these drugs…”
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Benzodiazepine and neuroactive steroid combinations in rats: anxiolytic-like and discriminative stimulus effects by Gunter, Barak W., Jones, Sherman A., Paul, Ian A., Platt, Donna M., Rowlett, James K.

“…Rationale Benzodiazepines are effective anxiolytics, hypnotics, and anticonvulsants but unwanted side effects, including abuse potential, limit their use. A…”
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Novel environment response as a predictor of midazolam self-administration in rats by Cook, James E, Huskinson, Sally L, Gunter, Barak W, Freeman, Kevin, Rowlett, James K

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Identification of a redox-sensitive switch within the JAK2 catalytic domain by Smith, John K., Patil, Chetan N., Patlolla, Srikant, Gunter, Barak W., Booz, George W., Duhé, Roy J.

“…Four cysteine residues (Cys866, Cys917, Cys1094, and Cys1105) have direct roles in cooperatively regulating Janus kinase 2 (JAK2) catalytic activity…”
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Selective inhibition of M5 muscarinic acetylcholine receptors attenuates cocaine self‐administration in rats by Gunter, Barak W., Gould, Robert W., Bubser, Michael, McGowan, Kevin M., Lindsley, Craig W., Jones, Carrie K.

“…Cocaine use disorder (CUD) remains a debilitating health problem in the United States for which there are no Food and Drug Administration‐approved treatment…”
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Evaluation of the anxiolytic-like, abuse-related, and sedative/motor effects of benzodiazepine and neuroactive steroid combinations in rats by Gunter, Barak W

“…Benzodiazepines are positive allosteric modulators of the GABAA receptor and are effective at relieving the symptoms of anxiety but the use of these drugs is…”
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Abstract 2279: The response of breast cancer cell lines to HET0016 alone or in combination with other chemotherapeutics by Slaughter, Tiffani, Gunter, Barak W., Fan, Fan, Huang, Chenghui, Pannuti, Antonio, Baker, Rodney C., Falck, John R., Miele, Lucio, Roman, Richard J., Duhe, Roy J.

“…Abstract One of the vexing problems in controlling breast cancer is the emergence of acquired endocrine-resistance in estrogen receptor positive breast cancers…”
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