Search Results - "Guns, Pieter‐Jan D F"

P2Y receptors and atherosclerosis in apolipoprotein E‐deficient mice by Guns, Pieter‐Jan DF, Hendrickx, Jan, Van Assche, Tim, Fransen, Paul, Bult, Hidde

“…Background and purpose:  P2Y nucleotide receptors are involved in the regulation of vascular tone, smooth muscle cell (SMC) proliferation and inflammatory…”
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Pharmacological characterization of nucleotide P2Y receptors on endothelial cells of the mouse aorta by Guns, Pieter‐Jan D F, Korda, András, Crauwels, Herta M, Van Assche, Tim, Robaye, Bernard, Boeynaems, Jean‐Marie, Bult, Hidde

“…Nucleotides regulate various effects including vascular tone. This study was aimed to characterize P2Y receptors on endothelial cells of the aorta of C57BL6…”
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Doxorubicin Impairs Smooth Muscle Cell Contraction: Novel Insights in Vascular Toxicity by Bosman, Matthias, Krüger, Dustin N, Favere, Kasper, Wesley, Callan D, Neutel, Cédric H G, Van Asbroeck, Birgit, Diebels, Owen R, Faes, Bart, Schenk, Timen J, Martinet, Wim, De Meyer, Guido R Y, Van Craenenbroeck, Emeline M, Guns, Pieter-Jan D F

“…Clinical and animal studies have demonstrated that chemotherapeutic doxorubicin (DOX) increases arterial stiffness, a predictor of cardiovascular risk. Despite…”
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Serum Corticosterone and Insulin Resistance as Early Biomarkers in the hAPP23 Overexpressing Mouse Model of Alzheimer’s Disease by Hendrickx, Jhana O., De Moudt, Sofie, Calus, Elke, Martinet, Wim, Guns, Pieter-Jan D. F., Roth, Lynn, De Deyn, Peter P., Van Dam, Debby, De Meyer, Guido R. Y.

“…Increasing epidemiological evidence highlights the association between systemic insulin resistance and Alzheimer’s disease (AD). As insulin resistance can be…”
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Endothelium‐dependent relaxation evoked by ATP and UTP in the aorta of P2Y2‐deficient mice by Guns, Pieter‐Jan D F, Van Assche, Tim, Fransen, Paul, Robaye, Bernard, Boeynaems, Jean‐Marie, Bult, Hidde

“…Based on pharmacological criteria, we previously suggested that in the mouse aorta, endothelium‐dependent relaxation by nucleotides is mediated by P2Y1…”
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Attenuated atherogenesis in apolipoprotein E-deficient mice lacking amyloid precursor protein by Van De Parre, Tim J.L, Guns, Pieter-Jan D.F, Fransen, Paul, Martinet, Wim, Bult, Hidde, Herman, Arnold G, De Meyer, Guido R.Y

“…Abstract Objective Recent evidence suggests that amyloid precursor protein (APP) is overexpressed in atherosclerosis-prone regions of mouse aorta. We therefore…”
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Doxorubicin induces arterial stiffness: A comprehensive in vivo and ex vivo evaluation of vascular toxicity in mice by Bosman, Matthias, Favere, Kasper, Neutel, Cédric H.G., Jacobs, Griet, De Meyer, Guido R.Y., Martinet, Wim, Van Craenenbroeck, Emeline M., Guns, Pieter-Jan D.F.

“…•Mice were treated with doxorubicin (DOX) for two weeks (4 mg/kg/week).•In vivo pulse wave velocity, a marker for arterial stiffness, was increased by DOX.•Ex…”
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Neuregulin-1 attenuates stress-induced vascular senescence by Shakeri, Hadis, Gevaert, Andreas B, Schrijvers, Dorien M, De Meyer, Guido R Y, De Keulenaer, Gilles W, Guns, Pieter-Jan D F, Lemmens, Katrien, Segers, Vincent F

“…Abstract Aims Cardiovascular ageing is a key determinant of life expectancy. Cellular senescence, a state of irreversible cell cycle arrest, is an important…”
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Endothelium‐dependent relaxation evoked by ATP and UTP in the aorta of P2Y 2 ‐deficient mice by Guns, Pieter‐Jan D F, Van Assche, Tim, Fransen, Paul, Robaye, Bernard, Boeynaems, Jean‐Marie, Bult, Hidde

“…Based on pharmacological criteria, we previously suggested that in the mouse aorta, endothelium‐dependent relaxation by nucleotides is mediated by P2Y 1…”
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Study of the involvement of purinergic receptors in the development of atherosclerotic plaques in the mouse by Guns, Pieter-Jan D. F

“…Introduction. Cardiovascular diseases resulting from atherosclerosis are a leading cause of death and morbidity in developed countries. Atherosclerosis is a…”
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Study of the involvement of purinergic receptors in the development of atherosclerotic plaques in the mouse by Guns, Pieter-Jan D. F

“…Introduction. Cardiovascular diseases resulting from atherosclerosis are a leading cause of death and morbidity in developed countries. Atherosclerosis is a…”
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