Cancer in First Nations people living in British Columbia, Canada: an analysis of incidence and survival from 1993 to 2010

Cancer in First Nations people living in British Columbia, Canada an analysis of incidence and survival from 1993 to 2010

Background For First Nations (FN) peoples living in British Columbia (BC), little is known regarding cancer in the population. The aim of this study was to explore cancer incidence and survival in the FN population of BC and compare it to the non-FN population. Methods All new cancers diagnosed from...

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Bibliographic Details
Published in:Cancer causes & control Vol. 28; no. 10; pp. 1105 - 1116
Main Authors: McGahan, Colleen E., Linn, Kevin, Guno, Preston, Johnson, Harmony, Coldman, Andrew J., Spinelli, John J., Caron, Nadine R.
Format: Journal Article
Language:English
Published: Cham Springer Science + Business Media 01-10-2017
Springer International Publishing
Springer Nature B.V
Subjects:
Aged
Biomedical and Life Sciences
Biomedicine
British Columbia - epidemiology
Cancer
Cancer Research
Cervical cancer
Cervix
Colorectal carcinoma
Epidemiology
Female
Health risk assessment
Hematology
Humans
Incidence
Indians, North American - statistics & numerical data
Lungs
Male
Middle Aged
Native North Americans
Neoplasms - epidemiology
Oncology
ORIGINAL PAPER
Proportional Hazards Models
Public Health
Survival
Survival Rate
Canada
Canada
First Nations
British Columbia
Survival
Cancer
Incidence
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Summary:Background For First Nations (FN) peoples living in British Columbia (BC), little is known regarding cancer in the population. The aim of this study was to explore cancer incidence and survival in the FN population of BC and compare it to the non-FN population. Methods All new cancers diagnosed from 1993 to 2010 were linked to the First Nations Client File (FNCF). Age-standardized incidence rates (ASIR) and rate ratios, and 1- and 5-year cause-specific survival estimates and hazard ratios were calculated. Follow-up end date for survival was December 31, 2011 and follow-up time was censored at a maximum of 15 years. Results ASIR of colorectal cancer (male SRR = 1.42, 95% CI 1.25–1.61; female SRR = 1.21, 95% CI 1.06–1.38) and cervical cancer (SRR = 1.84, 95% CI 1.45–2.33) were higher overall in FN residents in BC, compared to non-FN residents. Incidence rates of almost all other cancers were generally similar or lower in FN populations overall and by sex, age, and period categories, compared to non-FN residents. Trends in ASIR over time were similar except for lung (increasing for FN, decreasing for non-FN) and colorectal cancers (increasing for FN, decreasing for non-FN). Conversely, survival rates were generally lower for FN, with differences evident for some cancer sites at 1 year following diagnosis. Conclusion FN people living in BC face unique cancer issues compared to non-FN people. Higher incidence and lower survival associated with certain cancer types require further research to look into the likely multifaceted basis for these findings.
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ISSN:0957-5243
1573-7225
DOI:10.1007/s10552-017-0950-7