Search Results - "Gunn, R."

Soay Sheep Project by Gunn, R Graham

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Quantification of Oxygen Depletion During FLASH Irradiation In Vitro and In Vivo by Cao, Xu, Zhang, Rongxiao, Esipova, Tatiana V., Allu, Srinivasa Rao, Ashraf, Ramish, Rahman, Mahbubur, Gunn, Jason R., Bruza, Petr, Gladstone, David J., Williams, Benjamin B., Swartz, Harold M., Hoopes, P. Jack, Vinogradov, Sergei A., Pogue, Brian W.

“…Delivery of radiation at ultrahigh dose rates (UHDRs), known as FLASH, has recently been shown to preferentially spare normal tissues from radiation damage…”
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Are We on the Same Wavelength? Interpersonal Complementarity as Shared Cyclical Patterns During Interactions by Sadler, Pamela, Ethier, Nicole, Gunn, Gregory R, Duong, David, Woody, Erik

“…The present study addressed hypotheses about cyclical entrainment between interacting dyad members in their moment-to-moment levels of dominance and…”
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Structure-based charge calculations for predicting isoelectric point, viscosity, clearance, and profiling antibody therapeutics by Thorsteinson, Nels, Gunn, John R, Kelly, Kenneth, Long, Will, Labute, Paul

“…The effect of hydrophobicity on antibody aggregation is well understood, and it has been shown that charge calculations can be useful for high-concentration…”
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Glucagon increases energy expenditure independently of brown adipose tissue activation in humans by Salem, V., Izzi-Engbeaya, C., Coello, C., Thomas, D. B., Chambers, E. S., Comninos, A. N., Buckley, A., Win, Z., Al-Nahhas, A., Rabiner, E. A., Gunn, R. N., Budge, H., Symonds, M. E., Bloom, S. R., Tan, T. M., Dhillo, W. S.

“…Aims To investigate, for a given energy expenditure (EE) rise, the differential effects of glucagon infusion and cold exposure on brown adipose tissue (BAT)…”
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Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras by Carrière, Catherine, Young, Alison L., Gunn, Jason R., Longnecker, Daniel S., Korc, Murray

“…Chronic pancreatitis increases by 16-fold the risk of developing pancreatic ductal adenocarcinoma (PDAC), one of the deadliest human cancers. It also appears…”
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Incidence and Etiology of Potentially Preventable ICU Readmissions by Al-Jaghbeer, Mohammed J., Tekwani, Seema S., Gunn, Scott R., Kahn, Jeremy M.

“…OBJECTIVES:The rate of unplanned ICU readmissions is often considered a measure of hospital performance. However, the degree to which these readmissions are…”
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Bright environmental light improves the sleepiness of nightshift ICU nurses by Griepentrog, John E, Labiner, Hanna E, Gunn, Scott R, Rosengart, Matthew R

“…Shift work can disturb circadian homeostasis and result in fatigue, excessive sleepiness, and reduced quality of life. Light therapy has been shown to impart…”
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Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy by Cao, Xu, Rao Allu, Srinivasa, Jiang, Shudong, Jia, Mengyu, Gunn, Jason R., Yao, Cuiping, LaRochelle, Ethan P., Shell, Jennifer R., Bruza, Petr, Gladstone, David J., Jarvis, Lesley A., Tian, Jie, Vinogradov, Sergei A., Pogue, Brian W.

“…Hypoxia in solid tumors is thought to be an important factor in resistance to therapy, but the extreme microscopic heterogeneity of the partial pressures of…”
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Positron Emission Tomography Compartmental Models by Gunn, Roger N., Gunn, Steve R., Cunningham, Vincent J.

“…The current article presents theory for compartmental models used in positron emission tomography (PET). Both plasma input models and reference tissue input…”
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The mechanisms and treatment of asphyxial encephalopathy by Wassink, Guido, Gunn, Eleanor R, Drury, Paul P, Bennet, Laura, Gunn, Alistair J

“…Acute post-asphyxial encephalopathy occurring around the time of birth remains a major cause of death and disability. The recent seminal insight that allows…”
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Repurposing the Microsoft Kinect for Windows v2 for external head motion tracking for brain PET by Noonan, P J, Howard, J, Hallett, W A, Gunn, R N

“…Medical imaging systems such as those used in positron emission tomography (PET) are capable of spatial resolutions that enable the imaging of small,…”
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Recommendations for the validation of cell-based assays used for the detection of neutralizing antibody immune responses elicited against biological therapeutics by Gupta, Shalini, Devanarayan, Viswanath, Finco, Deborah, Gunn, George R., Kirshner, Susan, Richards, Susan, Rup, Bonita, Song, An, Subramanyam, Meena

“…The administration of biological therapeutics may result in the development of anti-drug antibodies (ADAs) in treated subjects. In some cases, ADA responses…”
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Dynamic dual-tracer MRI-guided fluorescence tomography to quantify receptor density in vivo by Davis, Scott C., Samkoe, Kimberley S., Tichauer, Kenneth M., Sexton, Kristian J., Gunn, Jason R., Deharvengt, Sophie J., Hasan, Tayyaba, Pogue, Brian W.

“…The up-regulation of cell surface receptors has become a central focus in personalized cancer treatment; however, because of the complex nature of contrast…”
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Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage by Carrière, Catherine, Young, Alison L, Gunn, Jason R, Longnecker, Daniel S, Korc, Murray

“…Targeting of oncogenic Kras to the pancreatic Nestin-expressing embryonic progenitor cells and subsequently to the adult acinar compartment and…”
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Consumer Engagement Strategies Among State Medicaid Agencies by Zhu, J., Rowland, R., Gunn, R., Gollust, S., Grande, D.

“…Research Objective To understand how state Medicaid agencies engage consumers in programmatic and administrative decision making, including motivations behind…”
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Characterization of the robust humoral immune response to GSK2618960, a humanized anti-IL-7 receptor monoclonal antibody, observed in healthy subjects in a Phase 1 study by Liao, Karen, Chen, Keguan, Brett, Sara, Gehman, Andrew, Schwartz, Ann M, Gunn, George R, DeWall, Stephen L

“…Interleukin-7 (IL-7) signaling modulates T cell activity and is implicated in numerous autoimmune diseases. An anti-IL-7 receptor monoclonal antibody…”
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Crimes of the Past: Defensive Temporal Distancing in the Face of Past In-Group Wrongdoing by Peetz, Johanna, Gunn, Gregory R., Wilson, Anne E.

“…Relegating past in-group transgressions to ancient history might deflect threat to collective identity. Germans (but not Canadians) judged the Holocaust to be…”
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Toxicity and Pharmacokinetic Profile for Single-Dose Injection of ABY-029: a Fluorescent Anti-EGFR Synthetic Affibody Molecule for Human Use by Samkoe, Kimberley S., Gunn, Jason R., Marra, Kayla, Hull, Sally M., Moodie, Karen L., Feldwisch, Joachim, Strong, Theresa V., Draney, Daniel R., Hoopes, P. Jack, Roberts, David W., Paulsen, Keith, Pogue, Brian W.

“…Purpose ABY-029, a synthetic Affibody peptide, Z03115-Cys, labeled with a near-infrared fluorophore, IRDye® 800CW, targeting epidermal growth factor receptor…”
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Mechanisms of Hypothermic Neuroprotection by Drury, Paul P., BSc, Gunn, Eleanor R., MBChB, Bennet, Laura, PhD, Gunn, Alistair J., MBChB, PhD

“…Prolonged, moderate cerebral hypothermia initiated within a few hours after severe hypoxia-ischemia and continued until resolution of the acute phase of…”
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