Search Results - "Guney, Tezcan"

First Inverse Electron-Demand Diels–Alder Methodology of 3‑Chloroindoles and Methyl Coumalate to Carbazoles by Guney, Tezcan, Lee, Jennifer J, Kraus, George A

“…The first successful inverse electron-demand Diels–Alder has been demonstrated with the 2-pyrone methyl coumalate in conjunction with substituted indoles…”
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Selective pyrone functionalization: reductive alkylation of triacetic acid lactone by Kraus, George A., Basemann, Kevin, Guney, Tezcan

“…[Display omitted] The one-pot reaction of aldehydes, triacetic acid lactone, and Hantzsch 1,4-dihydropyridine affords 3-alkyl pyrones via a reductive…”
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Synthesis of Benzannulated Medium‐ring Lactams via a Tandem Oxidative Dearomatization‐Ring Expansion Reaction by Guney, Tezcan, Wenderski, Todd A., Boudreau, Matthew W., Tan, Derek S.

“…Medium‐ring natural products exhibit diverse biological activities but such scaffolds are underrepresented in probe and drug discovery efforts due to the…”
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Total Synthesis of Paracaseolide A by Guney, Tezcan, Kraus, George A

“…The total synthesis of paracaseolide A, a valuable cell-cycle progression inhibitor, was accomplished in 8 steps from known compounds, with 6.6% overall yield…”
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Front Cover: Synthesis of Benzannulated Medium‐ring Lactams via a Tandem Oxidative Dearomatization‐Ring Expansion Reaction (Chem. Eur. J. 50/2018) by Guney, Tezcan, Wenderski, Todd A., Boudreau, Matthew W., Tan, Derek S.

“…Reversal of electron flow during a tandem oxidative dearomatization–ring‐expanding rearomatization reaction was inspired by the East River in New York City, a…”
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Synthesis of Benzannulated Medium‐Ring Lactams via a Tandem Oxidative Dearomatization‐Ring Expansion Reaction by Guney, Tezcan, Wenderski, Todd A., Boudreau, Matthew W., Tan, Derek S.

“…Invited for the cover of this issue is the group of Derek S. Tan at the Memorial Sloan Kettering Cancer Center. The image depicts the East River in New York…”
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Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa by Ji, Cheng, Sharma, Indrajeet, Pratihar, Debarshi, Hudson, L. Lynn, Maura, Damien, Guney, Tezcan, Rahme, Laurence G, Pesci, Everett C, Coleman, James P, Tan, Derek S

“…The Gram-negative bacterial pathogen Pseudomonas aeruginosa uses three interconnected intercellular signaling systems regulated by the transcription factors…”
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Heterocycles from wine: synthesis and biological evaluation of salidrosides by Guney, Tezcan, Kohles, Stephanie A., Thompson, Victoria L., Phillips, Gregory J., Kraus, George A.

“…Wine is composed of a variety of tannins, of which a sub-class includes salidrosides, which are largely uninvestigated compounds. The first syntheses of…”
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Kinetic Analyses of the Siderophore Biosynthesis Inhibitor Salicyl-AMS and Analogues as MbtA Inhibitors and Antimycobacterial Agents by Bythrow, Glennon V, Mohandas, Poornima, Guney, Tezcan, Standke, Lisa C, Germain, Gabrielle A, Lu, Xuequan, Ji, Cheng, Levendosky, Keith, Chavadi, Sivagami Sundaram, Tan, Derek S, Quadri, Luis E. N

“…There is a paramount need for expanding the drug armamentarium to counter the growing problem of drug-resistant tuberculosis. Salicyl-AMS, an inhibitor of…”
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Efficient synthesis of fluorescent rosamines: multifunctional platforms for cellular imaging by Kraus, George A., Guney, Tezcan, Kempema, Aaron, Hyman, Joel M., Parvin, Bahram

“…Substituted rosamines are efficiently prepared through a new organometallic addition to an imine-substituted xanthone as a novel primary amine equivalent. The…”
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Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa by Ji, Cheng, Sharma, Indrajeet, Pratihar, Debarshi, Hudson, L. Lynn, Maura, Damien, Guney, Tezcan, Rahme, Laurence G, Pesci, Everett C, Coleman, James P, Tan, Derek S

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