Search Results - "Gundle, R."

Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis by Al-Mossawi, M. H., Chen, L., Fang, H., Ridley, A., de Wit, J., Yager, N., Hammitzsch, A., Pulyakhina, I., Fairfax, B. P., Simone, D., Yi, Yao, Bandyopadhyay, S., Doig, K., Gundle, R, Kendrick, B., Powrie, F., Knight, J. C., Bowness, P.

“…Spondyloarthritis encompasses a group of common inflammatory diseases thought to be driven by IL-17A-secreting type-17 lymphocytes. Here we show increased…”
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Two-stage revision for prosthetic joint infection: predictors of outcome and the role of reimplantation microbiology by Bejon, P., Berendt, A., Atkins, B. L., Green, N., Parry, H., Masters, S., Mclardy-Smith, P., Gundle, R., Byren, I.

“…Objectives We describe rates of success for two-stage revision of prosthetic joint infection (PJI), including data on reimplantation microbiology. Methods We…”
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Opioid Use in Surgical Management in Musculoskeletal Oncology by Gazendam, Aaron M., Ghert, Michelle, Gundle, Kenneth R., Hayden, James B., Doung, Yee-Cheen

“…Opioid prescribing in the context of orthopaedic surgery has been recognized as having a critical role in the ongoing opioid epidemic. Given the negative…”
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Functional outcome of debridement, antibiotics and implant retention in periprosthetic joint infection involving the hip: a case-control study by Grammatopoulos, G, Bolduc, M-E, Atkins, B L, Kendrick, B J L, McLardy-Smith, P, Murray, D W, Gundle, R, Taylor, A H

“…Advocates of debridement, antibiotics and implant retention (DAIR) in hip periprosthetic joint infection (PJI) argue that a procedure not disturbing a sound…”
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One hundred and twelve infected arthroplasties treated with ‘DAIR’ (debridement, antibiotics and implant retention): antibiotic duration and outcome by Byren, I., Bejon, P., Atkins, B. L., Angus, B., Masters, S., McLardy-Smith, P., Gundle, R., Berendt, A.

“…Objectives We describe treatment failure rates by antibiotic duration for prosthetic joint infection (PJI) managed with debridement, antibiotics and implant…”
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Radiographic parameter-driven decision tree reliably predicts aseptic mechanical failure of compressive osseointegration fixation by Kagan, Ryland, Parlee, Lindsay, Beckett, Brooke, Hayden, James B, Gundle, Kenneth R, Doung, Yee-Cheen

“…Background and purpose - Compressive osseointegration fixation is an alternative to intramedullary fixation for endoprosthetic reconstruction. Mechanical…”
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Lumbar stiffness as a collateral outcome of spinal arthrodesis: a preliminary clinical study by Hart, Robert A., MD, Pro, Stephan L., MD, Gundle, Kenneth R., MD, Marshall, Lynn M., ScD

“…Abstract Background context Although spinal arthrodesis can improve function by correcting deformity and reducing pain, it also by intention reduces spinal…”
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Early, precise, and safe clinical evaluation of the pharmacodynamic effects of novel agents in the intact human tumor microenvironment by Gundle, Kenneth R, Rajasekaran, Karthik, Houlton, Jeffrey, Deutsch, Gary B, Ow, Thomas J, Maki, Robert G, Pang, John, Nathan, Cherie-Ann O, Clayburgh, Daniel, Newman, Jason G, Brinkmann, Elyse, Wagner, Michael J, Pollack, Seth M, Thompson, Matthew J, Li, Ryan J, Mehta, Vikas, Schiff, Bradley A, Wenig, Barry I, Swiecicki, Paul L, Tang, Alice L, Davis, Jessica L, van Zante, Annemieke, Bertout, Jessica A, Jenkins, Wendy, Turner, Atticus, Grenley, Marc, Burns, Connor, Frazier, Jason P, Merrell, Angela, Sottero, Kimberly H W, Derry, Jonathan M J, Gillespie, Kate C, Mills, Bre, Klinghoffer, Richard A

“…Drug development is systemically inefficient. Research and development costs for novel therapeutics average hundreds of millions to billions of dollars, with…”
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CORR Insights®: What Are the Trends in Research Publication Misrepresentation Among Orthopaedic Residency and Fellowship Applicants From 1996 to 2019? A Systematic Review by Gundle, Kenneth R.

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Compressive osseointegration for endoprosthetic reconstruction by Parlee, Lindsay, Kagan, Ryland, Doung, Yee-Cheen, Hayden, James B, Gundle, Kenneth R

“…This review summarizes the biomechanical concepts, clinical outcomes and limitations of compressive osseointegration fixation for endoprosthetic…”
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CORR Insights®: International Validation of the SORG Machine-learning Algorithm for Predicting the Survival of Patients with Extremity Metastases Undergoing Surgical Treatment by Gundle, Kenneth R.

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Lumbar Stiffness Disability Index: pilot testing of consistency, reliability, and validity by Hart, Robert A., MD, Gundle, Kenneth R., MD, Pro, Stephan L., MD, Marshall, Lynn M., ScD

“…Abstract Background context The primary goal of surgical arthrodesis is to eliminate the motion of spinal segments in an effort to alleviate pain, improve…”
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CORR Insights®: Does a Modified Technique to Achieve Arthrodesis of the Wrist After Resection of the Distal Radius and Translocating the Ipsilateral Ulna as a Vascularized Graft to Reconstruct the Defect Improve Grip Strength and Outcomes Scores? by Gundle, Kenneth R.

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Predictive outcomes of revision total hip replacement—A consecutive series of 1176 patients with a minimum 10-year follow-up by Philpott, A, Weston-Simons, J.S, Grammatopoulos, G, Bejon, P, Gill, H.S, Mclardy-Smith, P, Gundle, R, Murray, D.W, Pandit, H

“…Abstract The burden of revision total hip replacement (THR) surgery is increasing. With an increasing life expectancy and younger age of primary surgery this…”
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CORR Insights®: Psychosocial Factors Are Associated with Electronic Portal Registration by Gundle, Kenneth R.

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CORR Insights®: Do Massive Allograft Reconstructions for Tumors of the Femur and Tibia Survive 10 or More Years After Implantation? by Gundle, Kenneth R.

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Pseudotumours associated with metal-on-metal hip resurfacings by PANDIT, H, GLYN-JONES, S, MCLARDY-SMITH, P, GUNDLE, R, WHITWELL, D, GIBBONS, C. L. M, OSTLERE, S, ATHANASOU, N, GILL, H. S, MURRAY, D. W

“…We report 17 patients (20 hips) in whom metal-on-metal resurfacing had been performed and who presented with various symptoms and a soft-tissue mass which we…”
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Hip resurfacings revised for inflammatory pseudotumour have a poor outcome by GRAMMATOPOULOS, G, PANDIT, H, KWON, Y.-M, GUNDLE, R, MCLARDY-SMITH, P, BEARD, D. J, MURRAY, D. W, GILL, H. S

“…Inflammatory pseudotumours occasionally occur after metal-on-metal hip resurfacing and often lead to revision. Our aim was to determine the severity of this…”
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Reflections in a time of transition: orthopaedic faculty and resident understanding of accreditation schemes and opinions on surgical skills feedback by Gundle, Kenneth R., Mickelson, Dayne T., Hanel, Doug P.

“…Orthopaedic surgery is one of the first seven specialties that began collecting Milestone data as part of the Accreditation Council for Graduate Medical…”
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Rapid Web-Based Platform for Assessment of Orthopedic Surgery Patient Care Milestones: A 2-Year Validation by Gundle, Kenneth R., MD, Mickelson, Dayne T., MD, Cherones, Arien, AA, Black, Jason, AA, Hanel, Doug P., MD

“…Objective To determine the validity, feasibility, and responsiveness of a new web-based platform for rapid milestone-based evaluations of orthopedic surgery…”
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