Search Results - "Gundibasappa Karikannar, Nagaraja"
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Design and synthesis of some new pyrazolyl-pyrazolines as potential anti-inflammatory, analgesic and antibacterial agents
Published in European journal of medicinal chemistry (28-08-2015)“…In the present study, an efficient synthesis of some new substituted pyrazoline derivatives linked to a substituted pyrazole scaffold was performed by a…”
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Crystal, Hirshfeld, ADMET, drug-like and anticancer study of some newly synthesized imidazopyridine containing pyrazoline derivatives
Published in Journal of molecular structure (05-12-2019)“…To steer the selection of a potent drug, computer models have been fostered as a valid alternative to reduce pharmacokinetics related failure. The present…”
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1-{4-[(1-Isobutyl-1H-imidazo[4,5-c]quinolin-4yl)amino]phenyl}ethanone
Published in MolBank (01-12-2012)“…The title compound (3) is synthesized by the nucleophilic substitution of 4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline 2 with 4-amino acetophenone in…”
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Synthesis of new pyrazole derivatives via multicomponent reaction and evaluation of their antimicrobial and antioxidant activities
Published in Monatshefte für Chemie (01-09-2015)“…This work describes a facile synthesis and characterization of a new series of pyrazole containing pyrimidine, 1,4-dihydropyridine, and imidazole derivatives…”
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Synthesis of imidazo [1, 2-a]pyridine-chalcones as potent inhibitors against A549 cell line and their crystal studies
Published in Journal of molecular structure (05-02-2019)“…Trisubstituted imidazo [1,2-a]pyridines were synthesized, further it was engrossed into corresponding chalcones. Amongst, the crystal structures of 3b, 3f and…”
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Synthesis and pharmacological evaluation of some new fluorine containing hydroxypyrazolines as potential anticancer and antioxidant agents
Published in European journal of medicinal chemistry (02-11-2015)“…Breast cancer is probably the most prevalent cancer in women. The development of resistance to therapeutic agents and lack of targeted therapy for breast…”
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Synthesis, characterization of new imidazoquinonyl chalcones and pyrazolines as potential anticancer and antioxidant agents
Published in Medicinal chemistry research (01-09-2014)“…In the present work, we report the facile synthesis, characterization and anticancer, antioxidant study of new imidazoquinoline carrying biologically active…”
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Design, synthesis, and pharmacological studies of some new Mannich bases and S-alkylated analogs of pyrazole integrated 1,3,4-oxadiazole
Published in Research on chemical intermediates (01-03-2016)“…A facile and convenient synthesis of Mannich bases 5a – f and S -alkylated derivatives 6a – f and 7a – f has been carried out from the key intermediate…”
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One pot synthesis of thiazolo[2,3-b]dihydropyrimidinone possessing pyrazole moiety and evaluation of their anti-inflammatory and antimicrobial activities
Published in Medicinal chemistry research (2018)“…A series of pyrazole integrated thiazolo[2,3- b ]dihydropyrimidinone derivatives were synthesized as dual anti-inflammatory and antimicrobial agents. Among the…”
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Structural, spectral, and theoretical investigations of 5-methyl-1-phenyl-1H-pyrazole-4-carboxylic acid
Published in Research on chemical intermediates (01-05-2016)“…The present research work has focused on combined experimental and theoretical studies of one of the biologically important pyrazole-4-carboxylic acid…”
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Synthesis, characterization, single crystal X-ray diffraction and DFT studies of ethyl 5-methyl-1-phenyl-1H-pyrazole-4-carboxylate
Published in Molecular Crystals and Liquid Crystals (12-04-2016)“…The present study describes the synthesis, spectroscopic, and single crystal X-ray structural analysis of ethyl 5-methyl-1-phenyl-1H-pyrazole-4-carboxylate…”
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Ethyl 7-Methyl-5-(4-methylphenyl)-3-oxo-2-{[3-(3,4-dichlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
Published in MolBank (01-09-2012)“…A simple route for synthesis of compound 3 via three component reaction involving ethyl…”
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