Search Results - "Gundelfinger, E"

The presynaptic cytomatrix of brain synapses by Dresbach, T, Qualmann, B, Kessels, M M, Garner, C C, Gundelfinger, E D

“…Synapses are principal sites for communication between neurons via chemical messengers called neurotransmitters. Neurotransmitters are released from…”
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A comparison of the synaptic proteome in human chronic schizophrenia and rat ketamine psychosis suggest that prohibitin is involved in the synaptic pathology of schizophrenia by Smalla, K-H, Mikhaylova, M, Sahin, J, Bernstein, H-G, Bogerts, B, Schmitt, A, van der Schors, R, Smit, A B, Li, K W, Gundelfinger, E D, Kreutz, M R

“…Many studies in recent years suggest that schizophrenia is a synaptic disease that crucially involves a hypofunction of N -methyl-D-aspartate receptor-mediated…”
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ProSAP/Shank postsynaptic density proteins interact with insulin receptor tyrosine kinase substrate IRSp53 by Bockmann, J., Kreutz, M. R., Gundelfinger, E. D., Böckers, T. M.

“…The ProSAP/Shank family of multidomain proteins of the postsynaptic density (PSD) can either directly or indirectly interact with NMDA‐type and metabotropic…”
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Extensive remodeling of the presynaptic cytomatrix upon homeostatic adaptation to network activity silencing by Lazarevic, Vesna, Schöne, Cornelia, Heine, Martin, Gundelfinger, Eckart D, Fejtova, Anna

“…Global changes of activity in neuronal networks induce homeostatic adaptations of synaptic strengths, which involve functional remodeling of both presynaptic…”
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Three-Dimensional Architecture of Presynaptic Terminal Cytomatrix by Siksou, Lea, Rostaing, Philippe, Lechaire, Jean-Pierre, Boudier, Thomas, Ohtsuka, Toshihisa, Fejtova, Anna, Kao, Hung-Teh, Greengard, Paul, Gundelfinger, Eckart D, Triller, Antoine, Marty, Serge

“…Presynaptic terminals are specialized for mediating rapid fusion of synaptic vesicles (SVs) after calcium influx. The regulated trafficking of SVs likely…”
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Neurocan Is Dispensable for Brain Development by Zhou, Xiao-Hong, Brakebusch, Cord, Matthies, Henry, Oohashi, Toshitaka, Hirsch, Emilio, Moser, Markus, Krug, Manfred, Seidenbecher, Constanze I., Boeckers, Tobias M., Rauch, Uwe, Buettner, Reinhard, Gundelfinger, Eckart D., Fässler, Reinhard

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Epistatic interaction of genetic depression risk variants in the human subgenual cingulate cortex during memory encoding by Schott, B H, Assmann, A, Schmierer, P, Soch, J, Erk, S, Garbusow, M, Mohnke, S, Pöhland, L, Romanczuk-Seiferth, N, Barman, A, Wüstenberg, T, Haddad, L, Grimm, O, Witt, S, Richter, S, Klein, M, Schütze, H, Mühleisen, T W, Cichon, S, Rietschel, M, Noethen, M M, Tost, H, Gundelfinger, E D, Düzel, E, Heinz, A, Meyer-Lindenberg, A, Seidenbecher, C I, Walter, H

“…Recent genome-wide association studies have pointed to single-nucleotide polymorphisms (SNPs) in genes encoding the neuronal calcium channel Ca V 1.2 (CACNA1C;…”
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The Synaptic Glycoprotein Neuroplastin Is Involved in Long-Term Potentiation at Hippocampal CA1 Synapses by K.-H. Smalla, Matthies, H., Langnase, K., Shabir, S., Bockers, T. M., Wyneken, U., Staak, S., Krug, M., Beesley, P. W., Gundelfinger, E. D.

“…Neuroplastin-65 and -55 (previously known as gp65 and gp55) are glycoproteins of the Ig superfamily that are enriched in rat forebrain synaptic membrane…”
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Kainate-induced seizures alter protein composition and N-methyl- d-aspartate receptor function of rat forebrain postsynaptic densities by Wyneken, U, Smalla, K.-H, Marengo, J.J, Soto, D, de la Cerda, A, Tischmeyer, W, Grimm, R, Boeckers, T.M, Wolf, G, Orrego, F, Gundelfinger, E.D

“…The postsynaptic density is a highly dynamic structure, which is reorganized in an activity-dependent manner. An animal model for temporal lobe epilepsy, i.e…”
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Synaptic targeting and localization of Discs-large is a stepwise process controlled by different domains of the protein by Thomas, U., Ebitsch, S., Gorczyca, M., Koh, Y.H., Hough, C.D., Woods, D., Gundelfinger, E.D., Budnik, V.

“…Background: Membrane-associated guanylate kinases (MAGUKs) assemble ion channels, cell-adhesion molecules and components of second messenger cascades into…”
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SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A by KISTNER, U, WENZEL, B. M, VEH, R. W, CASES-LANGHOFF, C, GARNER, A. M, APPELTAUER, U, VOSS, B, GUNDELFINGER, E. D, GARNER, C. C

“…A novel synapse-associated protein, SAP90, accumulates around the axon hillock of Purkinje cells in rat cerebellum. By immuno-electron microscopy, SAP90 has…”
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The Calcium-independent Receptor for α-Latrotoxin from Human and Rodent Brains Interacts with Members of the ProSAP/SSTRIP/Shank Family of Multidomain Proteins by Kreienkamp, Hans-Jürgen, Zitzer, Heike, Gundelfinger, Eckart D., Richter, Dietmar, Böckers, Tobias M.

“…Subtypes of the calcium-independent receptors for α−latrotoxin (CIRL1–3) define a distinct subgroup within the large family of the seven-transmembrane region…”
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A reduced number of cortical neurons show increased Caldendrin protein levels in chronic schizophrenia by Bernstein, Hans-Gert, Sahin, Jale, Smalla, Karl-Heinz, Gundelfinger, Eckart D, Bogerts, Bernhard, Kreutz, Michael R

“…Abstract Caldendrin is a neuronal calcium sensor protein that is tightly associated with the postsynaptic density (PSD) of excitatory synapses. It has an…”
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Abnormal localization of two neuronal calcium sensor proteins, visinin-like proteins (vilips)-1 and -3, in neocortical brain areas of Alzheimer disease patients by Braunewell, K, Riederer, P, Spilker, C, Gundelfinger, E D, Bogerts, B, Bernstein, H G

“…The anatomical distribution of the neuronal calcium sensor proteins visinin-like protein-1 and -3 (VILIP-1 and -3) was investigated in various neocortical…”
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The Alzheimer disease-related calcium-binding protein Calmyrin is present in human forebrain with an altered distribution in Alzheimer's as compared to normal ageing brains by Bernstein, H.-G., Blazejczyk, M., Rudka, T., Gundelfinger, E. D., Dobrowolny, H., Bogerts, B., Kreutz, M. R., Kuznicki, J., Wojda, U.

“…The EF‐hand calcium binding protein Calmyrin (also called CIB‐1) was shown to interact with presenilin‐2 (PS‐2), suggesting that this interaction might play a…”
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The neuronal EF-hand calcium-binding protein visinin-like protein-3 is expressed in cerebellar Purkinje cells and shows a calcium-dependent membrane association by Spilker, C., Richter, K., Smalla, K.-H., Manahan-Vaughan, D., Gundelfinger, E.D., Braunewell, K.-H.

“…Visinin-like protein-3 is a member of the family of intracellular neuronal calcium sensors belonging to the superfamily of EF-hand proteins. Members of this…”
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Evidence for different functional properties of the neuronal calcium sensor proteins VILIP-1 and VILIP-3: from subcellular localization to cellular function by Spilker, C, Gundelfinger, E.D, Braunewell, K.-H

“…The visinin-like-proteins VILIP-1 and -3 are EF-hand calcium-binding proteins and belong to the family of neuronal calcium sensor (NCS) proteins. Members of…”
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Intracellular neuronal calcium sensor proteins: a family of EF-hand calcium-binding proteins in search of a function by Braunewell, K H, Gundelfinger, E D

“…Intracellular neuronal calcium sensors (NCS) constitute a rapidly growing family of calcium-binding proteins which belong to the superfamily of EF-hand…”
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Molecular determinants of presynaptic active zones by Garner, Craig C, Kindler, Stefan, Gundelfinger, Eckart D

“…The presynaptic cytoskeletal matrix (cytomatrix) assembled at active zones has been implicated in defining neurotransmitter release sites. Munc13, Rim, Bassoon…”
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Piccolo, a presynaptic zinc finger protein structurally related to bassoon by Fenster, S D, Chung, W J, Zhai, R, Cases-Langhoff, C, Voss, B, Garner, A M, Kaempf, U, Kindler, S, Gundelfinger, E D, Garner, C C

“…Piccolo is a novel component of the presynaptic cytoskeletal matrix (PCM) assembled at the active zone of neurotransmitter release. Analysis of its primary…”
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