Search Results - "Gunasekaran, Tamil Iniyan"

Polygenic score for Alzheimer’s disease identifies differential atrophy in hippocampal subfield volumes by Kannappan, Balaji, Gunasekaran, Tamil Iniyan, te Nijenhuis, Jan, Gopal, Muthu, Velusami, Deepika, Kothandan, Gugan, Lee, Kun Ho

“…Hippocampal subfield atrophy is a prime structural change in the brain, associated with cognitive aging and neurodegenerative diseases such as Alzheimer’s…”
Get full text

Diagnostic Blood Biomarkers in Alzheimer's Disease by Park, Jung Eun, Gunasekaran, Tamil Iniyan, Cho, Yeong Hee, Choi, Seong-Min, Song, Min-Kyung, Cho, Soo Hyun, Kim, Jahae, Song, Ho-Chun, Choi, Kyu Yeong, Lee, Jang Jae, Park, Zee-Yong, Song, Woo Keun, Jeong, Han-Seong, Lee, Kun Ho, Lee, Jung Sup, Kim, Byeong C

“…Potential biomarkers for Alzheimer's disease (AD) include amyloid β (Aβ ), t-Tau, p-Tau , neurofilament light chain (NFL), and neuroimaging biomarkers. Their…”
Get full text

Multi‐cohort genome‐wide association study on flortaucipir PET identifies novel risk loci associated with tau deposition and its role in AD pathology by Gunasekaran, Tamil Iniyan, Lee, Annie J, Dumitrescu, Logan C, Mormino, Elizabeth C., Sperling, Reisa A., Saykin, Andrew J., Hohman, Timothy J., Vardarajan, Badri N

“…Background Amyloid‐β plaques and tau neurofibrillary tangles are the pathological hallmarks of Alzheimer’s disease (AD). Previously, genetic studies on…”
Get full text

Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer’s disease by Bhattarai, Prabesh, Gunasekaran, Tamil Iniyan, Belloy, Michael E., Reyes-Dumeyer, Dolly, Jülich, Dörthe, Tayran, Hüseyin, Yilmaz, Elanur, Flaherty, Delaney, Turgutalp, Bengisu, Sukumar, Gauthaman, Alba, Camille, McGrath, Elisa Martinez, Hupalo, Daniel N., Bacikova, Dagmar, Le Guen, Yann, Lantigua, Rafael, Medrano, Martin, Rivera, Diones, Recio, Patricia, Nuriel, Tal, Ertekin-Taner, Nilüfer, Teich, Andrew F., Dickson, Dennis W., Holley, Scott, Greicius, Michael, Dalgard, Clifton L., Zody, Michael, Mayeux, Richard, Kizil, Caghan, Vardarajan, Badri N.

“…The risk of developing Alzheimer’s disease (AD) significantly increases in individuals carrying the APOEε4 allele. Elderly cognitively healthy individuals with…”
Get full text

Missense and loss‐of‐function variants at GWAS loci in familial Alzheimer's disease by Gunasekaran, Tamil Iniyan, Reyes‐Dumeyer, Dolly, Faber, Kelley M., Goate, Alison, Boeve, Brad, Cruchaga, Carlos, Pericak‐Vance, Margaret, Haines, Jonathan L., Rosenberg, Roger, Tsuang, Debby, Mejia, Diones Rivera, Medrano, Martin, Lantigua, Rafael A., Sweet, Robert A., Bennett, David A., Wilson, Robert S., Alba, Camille, Dalgard, Clifton, Foroud, Tatiana, Vardarajan, Badri N., Mayeux, Richard

“…BACKGROUND Few rare variants have been identified in genetic loci from genome‐wide association studies (GWAS) of Alzheimer's disease (AD), limiting…”
Get full text

P4‐095: ETHNIC VARIABILITY IN AGE AT ONSET FOR APOE ε4‐DEPENDENT β‐AMYLOID ACCUMULATION by Gunasekaran, Tamil Iniyan, Lee, Jang Jae, Choi, Yu Yong, Kang, Sarang, Choi, Kyu Yeong, Lee, Kun Ho

Get full text

ETHNIC VARIABILITY IN AGE AT ONSET FOR APOE ε4-DEPENDENT β-AMYLOID ACCUMULATION by Gunasekaran, Tamil Iniyan, Lee, Jang Jae, Choi, Yu Yong, Kang, Sarang, Choi, Kyu Yeong, Lee, Kun Ho

Get full text

Polygenic score for Alzheimer’s disease identifies differential atrophy in hippocampal subfield volumes by Balaji Kannappan, Tamil Iniyan Gunasekaran, Jan te Nijenhuis, Muthu Gopal, Deepika Velusami, Gugan Kothandan, Kun Ho Lee, for the Alzheimer’s Disease Neuroimaging Initiative

“…Hippocampal subfield atrophy is a prime structural change in the brain, associated with cognitive aging and neurodegenerative diseases such as Alzheimer’s…”
Get full text

A missense variant in SHARPIN mediates Alzheimer’s disease-specific brain damages by Park, Jun Young, Lee, Dongsoo, Lee, Jang Jae, Gim, Jungsoo, Gunasekaran, Tamil Iniyan, Choi, Kyu Yeong, Kang, Sarang, Do, Ah Ra, Jo, Jinyeon, Park, Juhong, Park, Kyungtaek, Li, Donghe, Lee, Sanghun, Kim, Hoowon, Dhanasingh, Immanuel, Ghosh, Suparna, Keum, Seula, Choi, Jee Hye, Song, Gyun Jee, Sael, Lee, Rhee, Sangmyung, Lovestone, Simon, Kim, Eunae, Moon, Seung Hwan, Kim, Byeong C., Kim, SangYun, Saykin, Andrew J., Nho, Kwangsik, Lee, Sung Haeng, Farrer, Lindsay A., Jun, Gyungah R., Won, Sungho, Lee, Kun Ho

“…Established genetic risk factors for Alzheimer’s disease (AD) account for only a portion of AD heritability. The aim of this study was to identify novel…”
Get full text

RISK PREDICTION OF ALZHEIMER'S DISEASE WITH AGE STRATIFICATION USING POLYGENIC RISK SCORES by Lee, Jang Jae, Kang, Sarang, Lee, Wooje, Gunasekaran, Tamil Iniyan, Gim, Jungsoo, Wi, Seong Ok, Kang, Dong Oan, Choo, Ilhan, Kim, Byeong Chae, Kim, Hoowon, Ikeuchi, Takeshi, Choi, Kyu Yeong, Lee, Kun Ho

Get full text

P1‐162: RISK PREDICTION OF ALZHEIMER'S DISEASE WITH AGE STRATIFICATION USING POLYGENIC RISK SCORES by Lee, Jang Jae, Kang, Sarang, Lee, Wooje, Gunasekaran, Tamil Iniyan, Gim, Jungsoo, Wi, Seong Ok, Kang, Dong Oan, Choo, Ilhan, Kim, Byeong Chae, Kim, Hoowon, Ikeuchi, Takeshi, Choi, Kyu Yeong, Lee, Kun Ho

Get full text

THE ASIAN ELDERLY ARE MORE VULNERABLE TO APOE ε4-DEPENDENT ONSET OF ALZHEIMER’S DISEASE by Choi, Kyu Yeong, Lee, Jang Jae, Gunasekaran, Tamil Iniyan, Kang, Sarang, Lee, Wooje, Lim, Ho Jae, Choi, Yu Yong, Seo, Eun Hyun, Lee, Seok Cheol, Gim, Jungsoo, Kim, Seok-Jun, Chung, Ji Yeon, Choo, Il Han, Kim, Hoowon, Kim, Byeong C., Lee, Kun Ho

Get full text

P3‐125: THE ASIAN ELDERLY ARE MORE VULNERABLE TO APOE ε4‐DEPENDENT ONSET OF ALZHEIMER'S DISEASE by Choi, Kyu Yeong, Lee, Jang Jae, Gunasekaran, Tamil Iniyan, Kang, Sarang, Lee, Wooje, Lim, Ho Jae, Choi, Yu Yong, Seo, Eun Hyun, Lee, Seok Cheol, Gim, Jungsoo, Kim, Seok-Jun, Chung, Ji Yeon, Choo, Il Han, Kim, Hoowon, Kim, Byeong C., Lee, Kun Ho

Get full text

ABCA7-dependent induction of neuropeptide Y is required for synaptic resilience in Alzheimer’s disease through BDNF/NGFR signaling by Tayran, Hüseyin, Yilmaz, Elanur, Bhattarai, Prabesh, Min, Yuhao, Wang, Xue, Ma, Yiyi, Wang, Ni, Jeong, Inyoung, Nelson, Nastasia, Kassara, Nada, Cosacak, Mehmet Ilyas, Dogru, Ruya Merve, Reyes-Dumeyer, Dolly, Stenersen, Jakob Mørkved, Reddy, Joseph S., Qiao, Min, Flaherty, Delaney, Gunasekaran, Tamil Iniyan, Yang, Zikun, Jurisch-Yaksi, Nathalie, Teich, Andrew F., Kanekiyo, Takahisa, Tosto, Giuseppe, Vardarajan, Badri N., İş, Özkan, Ertekin-Taner, Nilüfer, Mayeux, Richard, Kizil, Caghan

“…Genetic variants in ABCA7, an Alzheimer’s disease (AD)-associated gene, elevate AD risk, yet its functional relevance to the etiology is unclear. We generated…”
Get full text

APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer's Disease Risk in a Multiracial Sample by Choi, Kyu Yeong, Lee, Jang Jae, Gunasekaran, Tamil Iniyan, Kang, Sarang, Lee, Wooje, Jeong, Jangho, Lim, Ho Jae, Zhang, Xiaoling, Zhu, Congcong, Won, So-Yoon, Choi, Yu Yong, Seo, Eun Hyun, Lee, Seok Cheol, Gim, Jungsoo, Chung, Ji Yeon, Chong, Ari, Byun, Min Soo, Seo, Sujin, Ko, Pan-Woo, Han, Ji-Won, McLean, Catriona, Farrell, John, Lunetta, Kathryn L, Miyashita, Akinori, Hara, Norikazu, Won, Sungho, Choi, Seong-Min, Ha, Jung-Min, Jeong, Jee Hyang, Kuwano, Ryozo, Song, Min Kyung, An, Seong Soo A, Lee, Young Min, Park, Kyung Won, Lee, Ho-Won, Choi, Seong Hye, Rhee, Sangmyung, Song, Woo Keun, Lee, Jung Sup, Mayeux, Richard, Haines, Jonathan L, Pericak-Vance, Margaret A, Choo, I L Han, Nho, Kwangsik, Kim, Ki-Woong, Lee, Dong Young, Kim, SangYun, Kim, Byeong C, Kim, Hoowon, Jun, Gyungah R, Schellenberg, Gerard D, Ikeuchi, Takeshi, Farrer, Lindsay A, Lee, Kun Ho, Neuroimaging Initative, Alzheimer's Disease

“…Variants in the gene region may explain ethnic differences in the association of Alzheimer's disease (AD) with ε4. Ethnic differences in allele frequencies for…”
Get full text

P3‐083: Effects of Apoe Gene Polymorphisms on Late Onset Alzheimer’s Disease in a Korean Population by Choi, Kyu Yeong, Gunasekaran, Tamil Iniyan, Lee, Ji Su, Lee, Jang Jae, Kim, Na Hyeon, Kang, Sa Rang, Lee, Wooje, Choi, Yu Yong, Kim, Hoowon, Lee, Kun Ho

Get full text

ASSOCIATION STUDY OF HIGH-RISK GENETIC VARIANTS WITH ALZHEIMER'S DISEASE IN THE KOREAN ELDERLY by Lee, Ji Su, Kim, Na Hyeon, Gunasekaran, Tamil Iniyan, Kang, Sa Rang, Lee, Wooje, Lee, Jang Jae, Choi, Kyu Yeong, Lee, Kun Ho

Get full text

P2‐080: Association Study of High‐Risk Genetic Variants with Alzheimer's Disease in The Korean Elderly by Lee, Ji Su, Kim, Na Hyeon, Gunasekaran, Tamil Iniyan, Kang, Sa Rang, Lee, Wooje, Lee, Jang Jae, Choi, Kyu Yeong, Lee, Kun Ho

Get full text

EFFECTS OF APOE GENE POLYMORPHISMS ON LATE ONSET ALZHEIMER’S DISEASE IN A KOREAN POPULATION by Choi, Kyu Yeong, Gunasekaran, Tamil Iniyan, Lee, Ji Su, Lee, Jang Jae, Kim, Na Hyeon, Kang, Sa Rang, Lee, Wooje, Choi, Yu Yong, Kim, Hoowon, Lee, Kun Ho

Get full text

THE ASIAN ELDERLY ARE MORE SUSCEPTIBLE TO APOE ε4-DEPENDENT ONSET OF ALZHEIMER’S DISEASE by Choi, Kyu Yeong, Gunasekaran, Tamil Iniyan, Lee, Jang Jae, Kang, Sarang, Lee, Wooje, Choi, Yu Yong, Park, Sora, Chung, Ji Yeon, Kim, Byeong Chae, Choo, Il Han, Kim, Hoowon, Ikeuchi, Takeshi, Lee, Jung Sup, Lee, Kun Ho

Get full text