Search Results - "Gun, T."

Asbestos-related cancer in naval personnel: findings from participants in the British nuclear tests 1952–1967 by Gun, Richard T., Kendall, Gerry M.

“…Asbestos-containing materials (ACM) were present in British and Australian naval vessels throughout the twentieth century. The aim of this study was to…”
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EpCAM in carcinogenesis: the good, the bad or the ugly by van der Gun, Bernardina T.F., Melchers, Lieuwe J., Ruiters, Marcel H.J., de Leij, Lou F.M.H., McLaughlin, Pamela M.J., Rots, Marianne G.

“…The epithelial cell adhesion molecule (EpCAM) is a membrane glycoprotein that is highly expressed on most carcinomas and therefore of potential use as a…”
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Upregulation of endogenous ICAM‐1 reduces ovarian cancer cell growth in the absence of immune cells by Groote, Marloes L., Kazemier, Hinke G., Huisman, Christian, Gun, Bernardina T.F., Faas, Marijke M., Rots, Marianne G.

“…Ovarian cancer is a difficult‐to‐treat cancer with a 5‐year survival rate of only ∼45%, due to late diagnosis and therapy resistance. In need of new…”
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Circulating adipokine levels and COVID-19 severity in hospitalized patients by Flikweert, Antine W., Kobold, Anneke C. Muller, van der Sar-van der Brugge, Simone, Heeringa, Peter, Rodenhuis-Zybert, Izabela A., Bijzet, Johan, Tami, Adriana, van der Gun, Bernardina T. F., Wold, Karin I., Huckriede, Anke, Franke, Hildegard, Emmen, Judith M. A., Emous, Marloes, Grootenboers, Marco J. J. H., van Meurs, Matijs, van der Voort, Peter H. J., Moser, Jill

“…Background Obesity is a risk factor for adverse outcomes in COVID-19, potentially driven by chronic inflammatory state due to dysregulated secretion of…”
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Mild Coronavirus Disease 2019 (COVID-19) Is Marked by Systemic Oxidative Stress: A Pilot Study by van Eijk, Larissa E, Tami, Adriana, Hillebrands, Jan-Luuk, den Dunnen, Wilfred F A, de Borst, Martin H, van der Voort, Peter H J, Bulthuis, Marian L C, Veloo, Alida C M, Wold, Karin I, Vincenti González, María F, van der Gun, Bernardina T F, van Goor, Harry, Bourgonje, Arno R

“…Oxidative stress has been implicated to play a critical role in the pathophysiology of coronavirus disease 2019 (COVID-19) and may therefore be considered as a…”
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Update of mortality and cancer incidence in the Australian petroleum industry cohort by Gun, R T, Pratt, N, Ryan, P, Roder, D

“…Objectives: To update the analysis of the cohort mortality and cancer incidence study of employees in the Australian petroleum industry. Methods: Employees of…”
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Bidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer by van der Gun, B T F, Huisman, C, Stolzenburg, S, Kazemier, H G, Ruiters, M H J, Blancafort, P, Rots, M G

“…Background: The epithelial cell adhesion molecule (EpCAM) is overexpressed on most carcinomas. Dependent on the tumour type, its overexpression is either…”
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Transcription factors and molecular epigenetic marks underlying EpCAM overexpression in ovarian cancer by van der Gun, B T F, de Groote, M L, Kazemier, H G, Arendzen, A J, Terpstra, P, Ruiters, M H J, McLaughlin, P M J, Rots, M G

“…Background: The epithelial cell adhesion molecule (EpCAM) is overexpressed on carcinomas, and its downregulation inhibits the oncogenic potential of multiple…”
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Targeted DNA Methylation by a DNA Methyltransferase Coupled to a Triple Helix Forming Oligonucleotide To Down-Regulate the Epithelial Cell Adhesion Molecule by van der Gun, Bernardina T. F, Maluszynska-Hoffman, Maria, Kiss, Antal, Arendzen, Alice J, Ruiters, Marcel H. J, McLaughlin, Pamela M. J, Weinhold, Elmar, Rots, Marianne G

“…The epithelial cell adhesion molecule (EpCAM) is a membrane glycoprotein that has been identified as a marker of cancer-initiating cells. EpCAM is highly…”
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The gut microbiota as an early predictor of COVID-19 severity by Fabbrini, Marco, D'Amico, Federica, van der Gun, Bernardina T F, Barone, Monica, Conti, Gabriele, Roggiani, Sara, Wold, Karin I, Vincenti-Gonzalez, María F, de Boer, Gerolf C, Veloo, Alida C M, van der Meer, Margriet, Righi, Elda, Gentilotti, Elisa, Górska, Anna, Mazzaferri, Fulvia, Lambertenghi, Lorenza, Mirandola, Massimo, Mongardi, Maria, Tacconelli, Evelina, Turroni, Silvia, Brigidi, Patrizia, Tami, Adriana

“…Several studies reported alterations of the human gut microbiota (GM) during COVID-19. To evaluate the potential role of the GM as an early predictor of…”
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Serum insensitive, intranuclear protein delivery by the multipurpose cationic lipid SAINT-2 by VAN DER GUN, Bernardina T. F, MONAMI, Amélie, MCLAUGHLIN, Pamela M. J, LAARMANN, Sven, RASKO, Tamas, SLASKA-KISS, Krystyna, WEINHOLD, Elmar, WASSERKORT, Reinhold, DE LEIJ, Lou F. M. H, RUITERS, Marcel H. J, KISS, Antal

“…Cationic liposomal compounds are widely used to introduce DNA and siRNA into viable cells, but none of these compounds are also capable of introducing…”
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Mortality and cancer incidence of Australian participants in the British nuclear tests in Australia by Gun, R T, Parsons, J, Crouch, P, Ryan, P, Hiller, J E

“…Objectives:To investigate the mortality and cancer incidence of Australian nuclear test participants, and to identify any association with exposure to ionising…”
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The importance of immediate cooling—a case series of childhood burns in Vietnam by Nguyen, Nhu Lam, Gun, Richard T, Sparnon, Anthony L, Ryan, Philip

“…Numerous experimental studies have shown several benefits of treating burns by the immediate application of cool water. In this study of 695 children with…”
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Effects of a management team training intervention on the compliance with a surgical site infection bundle: a before–after study in operating theatres in the Netherlands by van Dijk, Manon D, van Beeck, Ed F, Huis, Anita, van der Gun, Bernardina TF, Polinder, Suzanne, van Eijsden, Rianne AM, Burdorf, Alex, Vos, Margreet C, Erasmus, Vicki

“…ObjectivesTo assess the effects of a quality improvement (QI) team training intervention, by measuring the intervention fidelity and the compliance with a…”
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Persistent downregulation of the pancarcinoma‐associated epithelial cell adhesion molecule via active intranuclear methylation by van der Gun, Bernardina T.F., Wasserkort, Reinhold, Monami, Amélie, Jeltsch, Albert, Raskó, Tamás, Ślaska‐Kiss, Krystyna, Cortese, Rene, Rots, Marianne G., de Leij, Lou F.M.H., Ruiters, Marcel H.J., Kiss, Antal, Weinhold, Elmar, McLaughlin, Pamela M.J.

“…The epithelial cell adhesion molecule (EpCAM) is expressed at high levels on the surface of most carcinoma cells. SiRNA silencing of EpCAM expression leads to…”
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Endonucleases induced TRAIL-insensitive apoptosis in ovarian carcinoma cells by Geel, Tessa M., Meiss, Gregor, van der Gun, Bernardina T., Kroesen, Bart Jan, de Leij, Lou F., Zaremba, Mindaugas, Šilanskas, Arūnas, Kokkinidis, Michael, Pingoud, Alfred, Ruiters, Marcel H., McLaughlin, Pamela M., Rots, Marianne G.

“…TRAIL induced apoptosis of tumor cells is currently entering phase II clinical settings, despite the fact that not all tumor types are sensitive to TRAIL…”
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Update of a prospective study of mortality and cancer incidence in the Australian petroleum industry by Gun, R T, Pratt, N L, Griffith, E C, Adams, G G, Bisby, J A, Robinson, K L

“…Aims: To update the analysis of the cohort mortality and cancer incidence study of employees in the Australian petroleum industry. Methods: Employees from 1981…”
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Effects of Molybdenum and Boron Additions of Fe-Based Metal Matrix Composites by Warm Compaction Method by Gün, T., Şimşir, M.

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Extending the Link Transmission Model with non-triangular fundamental diagrams and capacity drops by van der Gun, Jeroen P.T., Pel, Adam J., van Arem, Bart

“…•We extend the Link Transmission Model with continuous concave fundamental diagrams.•We extend LWR theory with inverted-lambda style diagrams having capacity…”
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The COVID HOME study research protocol: Prospective cohort study of non-hospitalised COVID-19 patients by Tami, Adriana, van der Gun, Bernardina T. F, Wold, Karin I, Vincenti-González, María F, Veloo, Alida C. M, Knoester, Marjolein, Harmsma, Valerie P. R, de Boer, Gerolf C, Huckriede, Anke L. W, Pantano, Daniele, Gard, Lilli, Rodenhuis-Zybert, Izabela A, Upasani, Vinit, Smit, Jolanda, Dijkstra, Akkelies E, de Haan, Jacco J, van Elst, Jip M, van den Boogaard, Jossy, O' Boyle, Shennae, Nacul, Luis, Niesters, Hubert G. M, Friedrich, Alex W

“…Background Guidelines on COVID-19 management are developed as we learn from this pandemic. However, most research has been done on hospitalised patients and…”
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