Search Results - "Gump, Jana L."
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ABCG2 expression, function, and promoter methylation in human multiple myeloma
Published in Blood (01-12-2006)“…We investigated the role of the breast cancer resistance protein (BCRP/ABCG2) in drug resistance in multiple myeloma (MM). Human MM cell lines, and MM patient…”
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The cytoplasmic trafficking of DNA topoisomerase IIα correlates with etoposide resistance in human myeloma cells
Published in Experimental cell research (01-05-2004)“…In this study we have investigated the role of topoisomerase (topo) IIα trafficking in cellular drug resistance. To accomplish this, it was necessary to…”
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Blocking a Topoisomerase IIα Nuclear Export Signal Sensitizes Human Multiple Myeloma Cells to Topoisomerase II Inhibitors
Published in Blood (20-11-2009)“…Abstract 2850 Poster Board II-826 We have previously demonstrated that topoisomerase IIa (topo IIa) is exported from the nucleus of high density human multiple…”
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4
The cytoplasmic trafficking of DNA topoisomerase IIalpha correlates with etoposide resistance in human myeloma cells
Published in Experimental cell research (01-05-2004)“…In this study we have investigated the role of topoisomerase (topo) IIalpha trafficking in cellular drug resistance. To accomplish this, it was necessary to…”
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Effects of wild-type p53 expression on the quantity and activity of topoisomerase IIα and β in various human cancer cell lines
Published in Journal of cellular biochemistry (01-11-1999)“…The p53 null HL‐60 cell line was transfected with plasmids coding for either the wild‐type p53 or mutant p53 gene. The stable expression of wild‐type p53…”
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Effects of wild-type p53 expression on the quantity and activity of topoisomerase II? and ? in various human cancer cell lines
Published in Journal of cellular biochemistry (01-11-1999)Get full text
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7
Quantitative immunofluorescence and immunoelectron microscopy of the topoisomerase IIα associated with nuclear matrices from wild-type and drug-resistant Chinese hamster ovary cell lines
Published in Journal of cellular biochemistry (01-10-1997)“…Topo IIα is considered an important constituent of the nuclear matrix, serving as a fastener of DNA loops to the underlying filamentous scaffolding network. To…”
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