Search Results - "Guminski, A D"

OpACIN-neo: A multicenter phase II study to identify the optimal neo-adjuvant combination scheme of ipilimumab (IPI) and nivolumab (NIVO) by Blank, C.U., Rozeman, E.A., Menzies, A.M., van de Wiel, B.A., Adhikari, C., Sikorska, K., Krijgsman, O., Eriksson, H., Bierman, C., Grijpink-Ongering, L., Gonzalez, M., Broeks, A., Guminski, A.D., Spillane, A.J., Klop, W.M.C., Saw, R.P.M., Scolyer, R.A., van Akkooi, A.C.J., Hansson, J., Long, G.V.

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FDG-PET response and outcome from anti-PD-1 therapy in metastatic melanoma by Tan, A.C., Emmett, L., Lo, S., Liu, V., Kapoor, R., Carlino, M.S., Guminski, A.D., Long, G.V., Menzies, A.M.

“…Immune checkpoint inhibitor therapy has resulted in impressive and durable clinical activity for many cancers including melanoma; however, there remain few…”
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Pathological response and tumour bed histopathological features correlate with survival following neoadjuvant immunotherapy in stage III melanoma by Rawson, R.V., Adhikari, C., Bierman, C., Lo, S.N., Shklovskaya, E., Rozeman, E.A., Menzies, A.M., van Akkooi, A.C.J., Shannon, K.F., Gonzalez, M., Guminski, A.D., Tetzlaff, M.T., Stretch, J.R., Eriksson, H., van Thienen, J.V., Wouters, M.W., Haanen, J.B.A.G., Klop, W.M.C., Zuur, C.L., van Houdt, W.J., Nieweg, O.E., Ch'ng, S., Rizos, H., Saw, R.P.M., Spillane, A.J., Wilmott, J.S., Blank, C.U., Long, G.V., van de Wiel, B.A., Scolyer, R.A.

“…Guidelines for pathological evaluation of neoadjuvant specimens and pathological response categories have been developed by the International Neoadjuvant…”
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Carboplatin and paclitaxel interact antagonistically in a megakaryoblast cell line - a potential mechanism for paclitaxel-mediated sparing of carboplatin-induced thrombocytopenia by GUMINSKI, Alexander D, HARNETT, Paul R, DEFAZIO, Anna

“…Clinical observation has shown that paclitaxel ameliorates the antiplatelet toxicity of carboplatin when the two drugs are combined, although antitumour…”
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LBA42OpACIN-neo: A multicenter phase II study to identify the optimal neo-adjuvant combination scheme of ipilimumab (IPI) and nivolumab (NIVO) by Blank, C U, Rozeman, E A, Menzies, A M, van de Wiel, B A, Adhikari, C, Sikorska, K, Krijgsman, O, Eriksson, H, Bierman, C, Grijpink-Ongering, L, Gonzalez, M, Broeks, A, Guminski, A D, Spillane, A J, Klop, W M C, Saw, R P M, Scolyer, R A, van Akkooi, A C J, Hansson, J, Long, G V

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MRP2 (ABCC2) and cisplatin sensitivity in hepatocytes and human ovarian carcinoma by Guminski, Alexander D., Balleine, Rosemary L., Chiew, Yoke-Eng, Webster, Lucy R., Tapner, Michael, Farrell, Geoffrey C., Harnett, Paul R., deFazio, Anna

“…The ABC transporter MRP2 (ABCC2) can mediate cisplatin efflux, and over-expression of MRP2 has been associated with cisplatin resistance in cancer cell lines…”
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Scientists and clinicians test their metal-back to the future with platinum compounds by Guminski, Alexander D, Harnett, Paul R, deFazio, Anna

“…After more than two decades of extensive use, drugs based on platinum continue to have a major role in cancer treatment. Although systematic approaches to the…”
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