Search Results - "Gumbilai, Valentino"
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Different sites of actions make different responses to thiazolidinediones between mouse and rat models of fatty liver
Published in Scientific reports (10-01-2022)“…Therapeutic approach for NAFLD is limited and there are no approved drugs. Pioglitazone (PGZ), a thiazolidinedione (TZD) that acts via peroxisome proliferator…”
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Seipin is necessary for normal brain development and spermatogenesis in addition to adipogenesis
Published in Human molecular genetics (01-08-2015)“…Seipin, encoded by BSCL2 gene, is a protein whose physiological functions remain unclear. Mutations of BSCL2 cause the most-severe form of congenital…”
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Leptin restores the insulinotropic effect of exenatide in a mouse model of type 2 diabetes with increased adiposity induced by streptozotocin and high-fat diet
Published in American journal of physiology: endocrinology and metabolism (15-10-2014)“…Leptin may reduce pancreatic lipid deposition, which increases with progression of obesity and can impair β-cell function. The insulinotropic effect of…”
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Fat Mass Reduction With Adipocyte Hypertrophy and Insulin Resistance in Heterozygous PPARγ Mutant Rats
Published in Diabetes (New York, N.Y.) (01-10-2016)“…Agonist-induced activation of peroxisome proliferator-activated receptor-γ (PPARγ) stimulates adipocyte differentiation and insulin sensitivity. Patients with…”
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Fat Mass Reduction With Adipocyte Hypertrophy and Insulin Resistance in Heterozygous PPAR[gamma] Mutant Rats
Published in Diabetes (New York, N.Y.) (01-10-2016)“…Agonist-induced activation of peroxisome proliferator-activated receptor-[gamma] (PPAR[gamma]) stimulates adipocyte differentiation and insulin sensitivity…”
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