Search Results - "Guma, Anna"

Axillary lymph node dissection versus radiotherapy in breast cancer with positive sentinel nodes after neoadjuvant therapy (ADARNAT trial) by Garcia-Tejedor, Amparo, Ortega-Exposito, Carlos, Salinas, Sira, Luzardo-González, Ana, Falo, Catalina, Martinez-Pérez, Evelyn, Pérez-Montero, Héctor, Soler-Monsó, M. Teresa, Bajen, Maria-Teresa, Benitez, Ana, Ortega, Raul, Petit, Anna, Guma, Anna, Campos, Miriam, Plà, Maria J., Pernas, Sonia, Peñafiel, Judith, Yeste, Carlos, Gil-Gil, Miguel, Guedea, Ferran, Ponce, Jordi, Laplana, Maria

“…Introduction Breast cancer surgery currently focuses on de-escalating treatment without compromising patient survival. Axillary radiotherapy (ART) now replaces…”
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Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness by Ruiz de Garibay, Gorka, Herranz, Carmen, Llorente, Alicia, Boni, Jacopo, Serra-Musach, Jordi, Mateo, Francesca, Aguilar, Helena, Gómez-Baldó, Laia, Petit, Anna, Vidal, August, Climent, Fina, Hernández-Losa, Javier, Cordero, Álex, González-Suárez, Eva, Sánchez-Mut, José Vicente, Esteller, Manel, Llatjós, Roger, Varela, Mar, López, José Ignacio, García, Nadia, Extremera, Ana I, Gumà, Anna, Ortega, Raúl, Plà, María Jesús, Fernández, Adela, Pernas, Sònia, Falo, Catalina, Morilla, Idoia, Campos, Miriam, Gil, Miguel, Román, Antonio, Molina-Molina, María, Ussetti, Piedad, Laporta, Rosalía, Valenzuela, Claudia, Ancochea, Julio, Xaubet, Antoni, Casanova, Álvaro, Pujana, Miguel Angel

“…Lymphangioleiomyomatosis (LAM) is a rare lung-metastasizing neoplasm caused by the proliferation of smooth muscle-like cells that commonly carry…”
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Semicarbazide-Sensitive Amine Oxidase/Vascular Adhesion Protein-1 Activity Exerts an Antidiabetic Action in Goto-Kakizaki Rats by ABELLA, Anna, MARTI, Luc, TESTAR, Xavier, ZORZANO, Antonio, CAMPS, Marta, CLARET, Marc, FERNANDEZ-ALVAREZ, J, GOMIS, Ramon, GUMA, Anna, VIGUERIE, Nathalie, CARPENE, Christian, PALACIN, Manuel

“…Semicarbazide-Sensitive Amine Oxidase/Vascular Adhesion Protein-1 Activity Exerts an Antidiabetic Action in Goto-Kakizaki Rats Anna Abella 1 , Luc Marti 1 ,…”
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Hepatic metastases from colorectal cancer: preoperative detection and assessment of resectability with helical CT by Valls, C, Andía, E, Sánchez, A, Gumà, A, Figueras, J, Torras, J, Serrano, T

“…To prospectively evaluate helical computed tomography (CT) in the preoperative detection of hepatic metastases and assessment of resectability with surgical,…”
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Disruption of mitochondrial dynamics triggers muscle inflammation through interorganellar contacts and mitochondrial DNA mislocation by Irazoki, Andrea, Gordaliza-Alaguero, Isabel, Frank, Emma, Giakoumakis, Nikolaos Nikiforos, Seco, Jordi, Palacín, Manuel, Gumà, Anna, Sylow, Lykke, Sebastián, David, Zorzano, Antonio

“…Some forms of mitochondrial dysfunction induce sterile inflammation through mitochondrial DNA recognition by intracellular DNA sensors. However, the…”
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GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK by Aguilar-Recarte, David, Barroso, Emma, Gumà, Anna, Pizarro-Delgado, Javier, Peña, Lucía, Ruart, Maria, Palomer, Xavier, Wahli, Walter, Vázquez-Carrera, Manuel

“…Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) activates AMP-activated protein kinase (AMPK) and plays a crucial role in glucose and lipid…”
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Neuregulin, an Effector on Mitochondria Metabolism That Preserves Insulin Sensitivity by Gumà, Anna, Díaz-Sáez, Francisco, Camps, Marta, Zorzano, Antonio

“…Various external factors modulate the metabolic efficiency of mitochondria. This review focuses on the impact of the growth factor neuregulin and its ErbB…”
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Neoadjuvant sunitinib plus exemestane in post-menopausal women with hormone receptor-positive/HER2-negative early-stage breast cancer (SUT_EXE-08): a phase I/II trial by Fullana, Bartomeu, Morales, Serafín, Petit, Anna, Alay, Ania, Verdaguer, Helena, Climent, Fina, Navarro-Perez, Valentí, Cejuela, Mónica, Galvan, Patricia, Gumà, Anna, Llombart-Cussac, Antonio, Cordero, David, Casanovas, Oriol, Prat, Aleix, Gil-Gil, Miguel, Pernas, Sonia

“…Neoadjuvant endocrine therapy (NET) for hormone receptor-positive (HR+) breast cancer might be as effective as chemotherapy, with a better toxicity profile…”
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Coordination of mitochondrial and lysosomal homeostasis mitigates inflammation and muscle atrophy during aging by Irazoki, Andrea, Martinez‐Vicente, Marta, Aparicio, Pilar, Aris, Cecilia, Alibakhshi, Esmaeil, Rubio‐Valera, Maria, Castellanos, Juan, Lores, Luis, Palacín, Manuel, Gumà, Anna, Zorzano, Antonio, Sebastián, David

“…Sarcopenia is one of the main factors contributing to the disability of aged people. Among the possible molecular determinants of sarcopenia, increasing…”
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The relevance of EGFR, ErbB receptors and neuregulins in human adipocytes and adipose tissue in obesity by Latorre, Jèssica, Martínez, Cristina, Ortega, Francisco, Oliveras-Cañellas, Núria, Díaz-Sáez, Francisco, Aragonés, Julian, Camps, Marta, Gumà, Anna, Ricart, Wifredo, Fernández-Real, José Manuel, Moreno-Navarrete, José María

“…To investigate the potential role of EGFR, ErbBs receptors and neuregulins in human adipose tissue physiology in obesity. Gene expression analysis in human…”
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Aquaglyceroporins Are Differentially Expressed in Beige and White Adipocytes by da Silva, Inês Vieira, Díaz-Sáez, Francisco, Zorzano, António, Gumà, Anna, Camps, Marta, Soveral, Graça

“…Browning of white adipocytes has been proposed as a powerful strategy to overcome metabolic complications, since brown adipocytes are more catabolic, expending…”
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Neuregulin 4 Is a Novel Marker of Beige Adipocyte Precursor Cells in Human Adipose Tissue by Comas, Ferran, Martínez, Cristina, Sabater, Mònica, Ortega, Francisco, Latorre, Jessica, Díaz-Sáez, Francisco, Aragonés, Julian, Camps, Marta, Gumà, Anna, Ricart, Wifredo, Fernández-Real, José Manuel, Moreno-Navarrete, José María

“…Nrg4 expression has been linked to brown adipose tissue activity and browning of white adipocytes in mice. Here, we aimed to investigate whether these…”
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Neuregulin 4 Downregulation Induces Insulin Resistance in 3T3-L1 Adipocytes through Inflammation and Autophagic Degradation of GLUT4 Vesicles by Díaz-Sáez, Francisco, Blanco-Sinfreu, Carla, Archilla-Ortega, Adrià, Sebastian, David, Romero, Montserrat, Hernández-Alvarez, Maria Isabel, Mora, Sílvia, Testar, Xavier, Ricart, Wifredo, Fernández-Real, José Manuel, Moreno-Navarrete, José María, Aragonés, Julián, Camps, Marta, Zorzano, Antonio, Gumà, Anna

“…The adipokine Neuregulin 4 (Nrg4) protects against obesity-induced insulin resistance. Here, we analyze how the downregulation of Nrg4 influences insulin…”
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VLDL and apolipoprotein CIII induce ER stress and inflammation and attenuate insulin signalling via Toll-like receptor 2 in mouse skeletal muscle cells by Botteri, Gaia, Montori, Marta, Gumà, Anna, Pizarro, Javier, Cedó, Lídia, Escolà-Gil, Joan Carles, Li, Diana, Barroso, Emma, Palomer, Xavier, Kohan, Alison B., Vázquez-Carrera, Manuel

“…Aim/hypothesis Here, our aim was to examine whether VLDL and apolipoprotein (apo) CIII induce endoplasmic reticulum (ER) stress, inflammation and insulin…”
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Serum neuregulin 4 is negatively correlated with insulin sensitivity in humans and impairs mitochondrial respiration in HepG2 cells by Martínez, Cristina, Latorre, Jèssica, Ortega, Francisco, Arnoriaga-Rodríguez, María, Lluch, Aina, Oliveras-Cañellas, Núria, Díaz-Sáez, Francisco, Aragonés, Julian, Camps, Marta, Gumà, Anna, Ricart, Wifredo, Fernández-Real, José Manuel, Moreno-Navarrete, José María

“…Neuregulin 4 (NRG4) has been described to improve metabolic disturbances linked to obesity status in rodent models. The findings in humans are controversial…”
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Neuregulin improves response to glucose tolerance test in control and diabetic rats by López-Soldado, Iliana, Niisuke, Katrin, Veiga, Catarina, Adrover, Anna, Manzano, Anna, Martínez-Redondo, Vicente, Camps, Marta, Bartrons, Ramon, Zorzano, Antonio, Gumà, Anna

“…Neuregulin (NRG) is an EGF-related growth factor that binds to the tyrosine kinase receptors ErbB3 and ErbB4, thus inducing tissue development and muscle…”
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The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling by Botteri, Gaia, Salvadó, Laia, Gumà, Anna, Lee Hamilton, D., Meakin, Paul J., Montagut, Gemma, Ashford, Michael L.J., Ceperuelo-Mallafré, Victoria, Fernández-Veledo, Sonia, Vendrell, Joan, Calderón-Dominguez, María, Serra, Dolors, Herrero, Laura, Pizarro, Javier, Barroso, Emma, Palomer, Xavier, Vázquez-Carrera, Manuel

“…β-secretase/β-site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) is a key enzyme involved in Alzheimer's disease that has recently been implicated…”
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Emerging role of neuregulin as a modulator of muscle metabolism by Gumà, Anna, Martínez-Redondo, Vicente, López-Soldado, Iliana, Cantó, Carles, Zorzano, Antonio

“…Neuregulin was described initially as a neurotrophic factor involved in the formation of the neuromuscular junction in skeletal muscle. However, in recent…”
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Neuregulins Increase Mitochondrial Oxidative Capacity and Insulin Sensitivity in Skeletal Muscle Cells by CANTO, Caries, PICH, Sara, PAZ, José C, SANCHES, Rosario, MARTINEZ, Vicente, ORPINELL, Meritxell, PALACIN, Manuel, ZORZANO, Antonio, GUMA, Anna

“…Neuregulins Increase Mitochondrial Oxidative Capacity and Insulin Sensitivity in Skeletal Muscle Cells Carles Cantó , Sara Pich , José C. Paz , Rosario Sanches…”
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Breast Cancer Patient's Outcomes after Neoadjuvant Chemotherapy and Surgery at 5 and 10 Years for Stage II-III Disease by Falo, Catalina, Azcarate, Juan, Fernandez-Gonzalez, Sergi, Perez, Xavier, Petit, Ana, Perez, Héctor, Vethencourt, Andrea, Vazquez, Silvia, Laplana, Maria, Ales, Miriam, Stradella, Agostina, Fullana, Bartomeu, Pla, Maria J, Gumà, Anna, Ortega, Raul, Varela, Mar, Pérez, Diana, Ponton, Jose Luis, Cobo, Sara, Benitez, Ana, Campos, Miriam, Fernández, Adela, Villanueva, Rafael, Obadia, Veronica, Recalde, Sabela, Soler-Monsó, Teresa, Lopez-Ojeda, Ana, Martinez, Evelyn, Ponce, Jordi, Pernas, Sonia, Gil-Gil, Miguel, Garcia-Tejedor, Amparo

“…: Neoadjuvant chemotherapy in breast cancer offers the possibility to facilitate breast and axillary surgery; it is a test of chemosensibility in vivo with…”
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