Search Results - "Gulzar, Zulfiqar G."
-
1
mRNA-Seq of single prostate cancer circulating tumor cells reveals recapitulation of gene expression and pathways found in prostate cancer
Published in PloS one (07-11-2012)“…Circulating tumor cells (CTC) mediate metastatic spread of many solid tumors and enumeration of CTCs is currently used as a prognostic indicator of survival in…”
Get full text
Journal Article -
2
DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer
Published in Genome research (01-07-2011)“…Candidate gene-based studies have identified a handful of aberrant CpG DNA methylation events in prostate cancer. However, DNA methylation profiles have not…”
Get full text
Journal Article -
3
NUSAP1 expression is upregulated by loss of RB1 in prostate cancer cells
Published in The Prostate (01-04-2015)“…BACKGROUND Overexpression of NUSAP1 is associated with poor prognosis in prostate cancer, but little is known about what leads to its overexpression. Based on…”
Get full text
Journal Article -
4
Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns
Published in BMC cancer (17-04-2017)“…Current diagnostic tools for prostate cancer lack specificity and sensitivity for detecting very early lesions. DNA methylation is a stable genomic…”
Get full text
Journal Article -
5
Increased expression of GCNT1 is associated with altered O-glycosylation of PSA, PAP, and MUC1 in human prostate cancers
Published in The Prostate (01-07-2014)“…BACKGROUND Protein glycosylation is a common posttranslational modification and glycan structural changes have been observed in several malignancies including…”
Get full text
Journal Article -
6
Novel Fusion Transcripts Associate with Progressive Prostate Cancer
Published in The American journal of pathology (01-10-2014)“…The mechanisms underlying the potential for aggressive behavior of prostate cancer (PCa) remain elusive. In this study, whole genome and/or transcriptome…”
Get full text
Journal Article -
7
Increased expression of NuSAP in recurrent prostate cancer is mediated by E2F1
Published in Oncogene (03-01-2013)“…Increasing evidence suggests that prostate cancer is overdiagnosed and overtreated, and prognostic biomarkers would aid in treatment selection. To define…”
Get full text
Journal Article -
8
Abstract 2158: Increased expression of NuSAP gene in recurrent prostate cancer is mediated by E2F
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Increasing evidence suggests prostate cancer is over diagnosed and over treated. Identification of prognostic biomarkers would aid in treatment selection. To…”
Get full text
Journal Article -
9
Abstract B15: NuSAP is regulated by RB1 and modulates prostate cancer progression
Published in Cancer research (Chicago, Ill.) (01-10-2013)“…We have recently shown that nucleolar and spindle-associated protein (NUSAP1; encoding NuSAP) is overexpressed in recurrent prostate cancer tumors. Correlation…”
Get full text
Journal Article -
10