Search Results - "Gulyaeva, N V"

The Missing Link: How Exosomes and miRNAs can Help in Bridging Psychiatry and Molecular Biology in the Context of Depression, Bipolar Disorder and Schizophrenia by Gruzdev, S. K., Yakovlev, A. A., Druzhkova, T. A., Guekht, A. B., Gulyaeva, N. V.

“…MicroRNAs (miRNAs) only recently have been recognized as promising molecules for both fundamental and clinical neuroscience. We provide a literature review of…”
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Molecular and cellular mechanisms of sporadic Alzheimer’s disease: Studies on rodent models in vivo by Gulyaeva, N. V., Bobkova, N. V., Kolosova, N. G., Samokhin, A. N., Stepanichev, M. Yu, Stefanova, N. A.

“…In this review, recent data are presented on molecular and cellular mechanisms of pathogenesis of the most widespread (about 95%) sporadic forms of Alzheimer’s…”
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Biochemical Mechanisms and Translational Relevance of Hippocampal Vulnerability to Distant Focal Brain Injury: The Price of Stress Response by Gulyaeva, N. V.

“…Focal brain injuries (in particular, stroke and traumatic brain injury) induce with high probability the development of delayed (months, years) cognitive and…”
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Molecular mechanisms of neuroplasticity: An expanding universe by Gulyaeva, N. V.

“…Biochemical processes in synapses and other neuronal compartments underlie neuroplasticity (functional and structural alterations in the brain enabling…”
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Interplay between brain BDNF and glutamatergic systems: A brief state of the evidence and association with the pathogenesis of depression by Gulyaeva, N. V.

“…The excitatory neurotransmitter glutamate system and the brain-derived neurotrophic factor (BDNF) system are principally involved in phenomena of cellular and…”
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Augmented Cortisol and Antiglucocorticoid Therapy in Mood Disorders: the Hippocampus as a Potential Drug Target by Gulyaeva, N. V.

“…The pathophysiology of many mood disorders is closely related to abnormal stress response associated with the dysfunction of the hypothalamic–pituitary–adrenal…”
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New Technologies in the Diagnostics and Treatment of Brain Deseases: from Neurosciences to the Multidisciplinary Clinical Practice and Maintaining of Mental Health by Gulyaeva, N V, Akzhigitov, R G, Gersamiya, A G, Druzhkova, T A, Gekht, A B

“…Over the past years, the prevalence of brain diseases and, consequently, their social significance and economic burden for society has been steadily increasing…”
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Single intracerebroventricular administration of amyloid-beta (25–35) peptide induces impairment in short-term rather than long-term memory in rats by Stepanichev, M.Yu, Moiseeva, Yu.V, Lazareva, N.A, Onufriev, M.V, Gulyaeva, N.V

“…Ample experimental evidence indicates that intracerebral injection or infusion of amyloid-beta peptides (Aβ) to rodents induces learning and memory impairments…”
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Neuroendocrine Control of Hyperglutamatergic States in Brain Pathologies: the Effects of Glucocorticoids by Gulyaeva, N. V.

“…Neuroendocrine control mediated by glucocorticoids is important for maintaining the normal functioning of the brain and the balance between the excitation and…”
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Molecular Mechanisms of the Actions of Brain Peptide-Containing Drugs: Cortexin by Gulyaeva, N. V.

“…This article considers new data on the key molecular mechanisms which may underlie the neuroprotective properties of multicomponent organ-specific medicinal…”
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Effects of Single Injections of Brain-Derived Neurotrophic Factors into the Midline Ventral Tegmental Area on the Reinforcing Properties of Morphine by Peregud, D. I., Stepanichev, M. Yu, Lazareva, N. A., Panchenko, L. F., Gulyaeva, N. V.

“…The strong positive reinforcing effect of opiates is regarded as a trigger for the development of pathological dependence, though the neurobiological basis of…”
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Non-apoptotic functions of caspase-3 in nervous tissue by Gulyaeva, N V

“…Some enzymes that have been recognized as "apoptotic" so far may be involved in important cellular processes not necessarily related to cell death in nervous…”
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Markers of Neuroontogenesis in the Stress-Hyporesponsive Period: a Comparison of Laboratory Rodents and Humans by Manolova, A. O., Gulyaeva, N. V.

“…It is commonly accepted now that a number of neuropsychiatric diseases are associated with early life stress. Various rodent models are used to elucidate the…”
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Disorders of Olfaction – An Interdisciplinary Problem by Guekht, A. B., Kryukov, A. I., Kazakova, A. A., Akzhigitov, R. G., Gulyaeva, N. V., Druzhkova, T. A.

“…Olfactory impairment is a serious symptom requiring careful differential diagnosis. This article presents the current state of the field and presents evidence…”
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secreted caspase-3-substrate-cleaving activity at low pH belongs to cathepsin B: a study on primary brain cell cultures by Onufriev, M. V, Yakovlev, A. A, Lyzhin, A. A, Stepanichev, M. Yu, Khaspekov, L. G, Gulyaeva, N. V

“…The cysteine proteases caspase-3 and cathepsins are involved in both neuronal plasticity and neuropathology. Using primary neuroglial and glial cerebellar…”
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Modeling of Hypercorticosteronemia in Rats Using Osmotic Pumps by Onufriev, M. V., Moiseeva, Yu. V., Gulyaeva, N. V.

“…The administration of the adrenal hormone corticosterone by injection or subcutaneous implantation of its modified-release dosage forms is often used to model…”
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Neonatal Proinflammatory Stress and the Maturation of Intercellular Communication in the Hippocampus by Kudryashova, I. V., Stepanichev, M. Yu, Gulyaeva, N. V.

“…Neuroinflammatory processes, particularly those induced by infectious agents, are associated with activation of the microglia and subsequent increases in the…”
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Impaired Memory Formation and the Development of Transient Cholinergic Deficit in Mice after Olfactory Bulbectomy by Nedogreeva, O. A., Lazareva, N. A., Stepanichev, M. Yu, Gulyaeva, N. V.

“…Olfactory bulbectomy in rodents is widely used as a model of the symptoms of clinical depression and neurodegeneration, including cholinergic. Male C57BL/6…”
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Chronic Social Isolation Stress and Crowding in Rats Have Different Effects on Learning an Operant Behavior and the State of the Hypothalamo-Hypophyseal-Adrenocortical System by Gavrilov, V. V., Onufriev, M. V., Moiseeva, Yu. V., Alexandrov, Yu. I., Gulyaeva, N. V.

“…Social stress is a widely experienced problem in the contemporary world; it is diverse and is determined by specific living conditions in both humans and…”
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Effects of Selective Anxiolytic Afobazole on Active Caspase-3 by Antipova, T. A, Sapozhnikova, D. S, Stepanichev, M. Yu, Onufriev, M. V, Gulyaeva, N. V, Seredenin, S. B

“…We studied the effects of afobazole on apoptosis through active caspase-3. Afobazole in a final concentration of 10⁻⁸ M inhibits hyperactivation of effector…”
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