Search Results - "Gulsun, Tugba"
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Design and Characterization of Nanocrystal Formulations Containing Ezetimibe
Published in Chemical & Pharmaceutical Bulletin (01-01-2011)“…Ezetimibe is a lipid-lowering compound that selectively inhibits the absorption of cholesterol and related phytosterols from the intestine. As ezetimibe is…”
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Preparation of nanosuspensions of a 1,4-dihydropyridine-based mixed L-/T-type calcium channel blocker by combined precipitation and ultrasonication methods
Published in Journal of drug delivery science and technology (01-09-2023)“…M3, a condensed 1,4-dihydropyridine (DHP) derivative, targets both L- and T-type calcium channels and therefore, stands as a promising antihypertensive drug…”
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Development and characterization of pullulan-based orally disintegrating films containing amlodipine besylate
Published in European journal of pharmaceutical sciences (01-01-2021)“…•Hypertension is a common public health problem in all countries of the world.•Oral administration is the most preferred route of administration.•The…”
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Influence of permeability enhancers on the paracellular permeability of metformin hydrochloride and furosemide across Caco-2 cells
Published in Canadian journal of physiology and pharmacology (01-04-2023)“…Permeability enhancers can affect absorption of paracellularly transported drugs. This study aims to evaluate effects of permeability enhancers (chitosan,…”
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Development and characterization of trimethobenzamide hydrochloride containing orally disintegrating tablets
Published in Journal of drug delivery science and technology (01-10-2023)“…Orally disintegrating tablets have been developed to rapidly disintegrate in saliva within seconds after administration, without the need for drinking water or…”
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Electrospun nanofiber drug delivery systems and recent applications: An overview
Published in Journal of drug delivery science and technology (01-02-2024)“…Fiber technology plays a significant role in advancing drug research. While developing drug delivery systems, nanofiber technology has gained importance due to…”
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Development and characterization of orodispersible films containing amlodipine besylate and rosuvastatin calcium based on electrospun fibers
Published in Journal of drug delivery science and technology (01-11-2024)“…Amlodipine besylate (AML) and rosuvastatin calcium (ROS) are commonly used in the treatment of cardiovascular diseases such as hypertension, dyslipidemia, and…”
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Evaluation of drug permeability methods recommended by health authorities
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The development and characterization of electrospun gelatin nanofibers containing indomethacin and curcumin for accelerated wound healing
Published in Journal of drug delivery science and technology (01-01-2022)“…Nanofibers are frequently investigated to facilitate wound healing. In this study, gelatin nanofibers were produced that are biodegradable and biocompatible…”
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Preparation and characterization of furosemide nanosuspensions
Published in Journal of drug delivery science and technology (01-06-2018)“…Furosemide, a widely used loop diuretic, has a low aqueous solubility, and low permeability. Nanosuspensions have been widely used to increase the solubility…”
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Assessment of Dose Proportionality of Rivaroxaban Nanocrystals
Published in AAPS PharmSciTech (06-08-2020)“…Rivaroxaban (RXB) is a class II drug, according to the Biopharmaceutics Classification System. Since its bioavailability is low at high doses, dose…”
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Development and evaluation of terbutaline sulfate orally disintegrating tablets by direct compression and freeze drying methods
Published in Journal of drug delivery science and technology (01-08-2018)“…Asthma is a chronic respiratory condition characterized by attacks of spasm in the bronchi of the lungs, causing difficulty in breathing. Oral and inhalation…”
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Development and characterization of metformin hydrochloride- and glyburide-containing orally disintegrating tablets
Published in Pharmaceutical development and technology (13-09-2020)“…Diabetes is characterized by chronic hyperglycemia. Although metformin hydrochloride (MHCl)- and glyburide (GLB)-containing conventional tablets are available…”
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Characterization and comparison of deferasirox fast disintegrating tablets prepared by direct compression and lyophilization methods
Published in Journal of drug delivery science and technology (01-06-2020)“…The aim of this study was to develop direct compressed and lyophilized fast disintegrating/dissolving tablets (FDTs) that enhanced disintegration and…”
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Comparison of free vs. liposomal naringenin in white adipose tissue browning in C57BL/6j mice
Published in Journal of liposome research (19-09-2024)“…Naringenin may play a role in browning by increasing thermogenic gene expression. In this study, we encapsulated naringenin using a liposomal formulation and…”
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Evaluation of preparation methods for orally disintegrating tablets
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Preparation and characterization of nimesulide containing nanocrystal formulations
Published in Pharmaceutical development and technology (01-06-2013)“…The aim of this study was to develop and characterize nanocrystal formulation containing nimesulide. Physical mixture of drug and excipient…”
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