Search Results - "Gulsah Albayrak"

Immune modulation underpins the anti‐cancer activity of HDAC inhibitors by Blaszczak, Wiktoria, Liu, Geng, Zhu, Hong, Barczak, Wojciech, Shrestha, Amit, Albayrak, Gulsah, Zheng, Shunsheng, Kerr, David, Samsonova, Anastasia, La Thangue, Nicholas B.

“…Aberrant protein acetylation is strongly linked to tumorigenesis, and modulating acetylation through targeting histone deacetylase (HDAC) with small‐molecule…”
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Antitumorigenic Effect of Memantine via Interfering Glutamate Metabolism in Mouse 4T1 Breast Tumor Model by Albayrak, Gulsah, Korkmaz, Funda D, Bali, Elif B, Bagriacik, Emin U

“…Repurposing drug is an efficient strategy as the drug discovery process is timeconsuming, laborious and costly. Memantine is already used in Alzheimer's…”
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The HDAC inhibitor zabadinostat is a systemic regulator of adaptive immunity by Liu, Geng, Barczak, Wojciech, Lee, Lian Ni, Shrestha, Amit, Provine, Nicholas M., Albayrak, Gulsah, Zhu, Hong, Hutchings, Claire, Klenerman, Paul, La Thangue, Nicholas B.

“…Protein acetylation plays a key role in regulating cellular processes and is subject to aberrant control in diverse pathologies. Although histone deacetylase…”
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Bortezomib Potentiates the Effect of Roscovitine Via Dna Damage Induced Apoptosis in A549 Lung Cancer Cells by ALBAYRAK, Gülşah

“…The adoption of new treatment modalities remains crucial as lung cancer has one of the lowest survival rates, along with liver and pancreatic cancer…”
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Combination of Metformin and Dichloroacetate Inhibits Proliferation and Induce Intrinsic Pathway of Apoptosis in PC-3 Human Prostate Cancer Cells

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FOXA1 knock-out via CRISPR/Cas9 altered Casp-9, Bax, CCND1, CDK4, and fibronectin expressions in LNCaP cells by Albayrak, Gulsah, Konac, Ece, Ugras Dikmen, Asiye, Bilen, Cenk Y

“…Prostate cancer is one of the most common types of cancer in men and the leading cause of death in developed countries. With the aid of molecular and genetic…”
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Three essential human based projects that directs the medical biotechnology research and their future prospects by Albayrak, Gulsah, Yıldız, Ümit Yılmaz

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Sustained cancer-relevant alternative RNA splicing events driven by PRMT5 in high-risk neuroblastoma by Bate-Eya, Laurel Tabe, Albayrak, Gulsah, Carr, Simon Mark, Shrestha, Amit, Kanapin, Alexander, Samsonova, Anastasia, La Thangue, Nicholas Barrie

“…Protein arginine methyltransferase 5 (PRMT5) is over-expressed in a wide variety of cancers and is implicated as having a key oncogenic role, achieved in part…”
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Memantine shifts cancer cell metabolism via AMPK1/2 mediated energetic switch in A549 lung cancer cells by Albayrak, Gulsah, Demirtas Korkmaz, Funda

“…Memantine is used to prevent glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease. As glutamine is one of the major source of…”
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The outcomes of an impaired powerhouse in KRAS mutant lung adenocarcinoma cells by Elesclomol by Albayrak, Gulsah, Korkmaz, Funda Demirtas, Tozcu, Duygu, Dogan Turacli, Irem

“…Objectives Lung cancer stands out as the most common cancer type worldwide. The most common genetic alteration detected in adenocarcinoma patients is KRAS…”
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Do the expressions of epithelial–mesenchymal transition proteins, periostin, integrin-α4 and fibronectin correlate with clinico-pathological features and prognosis of metastatic castration-resistant prostate cancer? by Konac, Ece, Kiliccioglu, Ilker, Sogutdelen, Emrullah, Dikmen, Asiye U, Albayrak, Gulsah, Bilen, Cenk Y

“…Development of metastatic castration-resistant prostate cancer is a result of the lack of an apoptotic response by the tumor cells and loss of the ability to…”
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Targeting Cancer Cell Metabolism with Metformin, Dichloroacetate and Memantine in Glioblastoma (GBM) by Albayrak, Gulsah, Konac, Ece, Dere, Umit Akin, Emmez, Hakan

“…To investigate the effects of metformin, dichloroacetate (DCA), and memantine on T98G and U87-MG human glioblastoma (GBM) cells to target tumor cell metabolism…”
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Cyclophosphamide Inhibits PI3K/AKT/mTOR Signaling Pathway in Mice Kidneys by Gulsah Albayrak, Pinar Kilicarslan Sonmez, Damla Akogullari, Elgin Turkoz Uluer

“…Cyclophosphamide (CTX), also known as cytophosphane among other, is a medication used as chemotherapy and to suppress the immune system. The PI3K/AKT/mTOR…”
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Does memantine show chemopreventive effect against mice 4T1 breast tumor model? by Albayrak, Gülşah, Bali, Elif Burcu, Korkmaz, Funda Demirtaş, Bağrıaçık, Emin Ümit

“…Cancer cells express higher levels of N-methyl-d-aspartate (NMDA) receptor. In this study, we aimed to use memantine as a potential blocker to inhibit the…”
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Anticancer Effects of Oleocanthal and Pinus Pinaster on Breast Cancer Cell in Culture by Mahmud Özkut, Gülşah Albayrak, Pınar Kılıçaslan Sönmez, Büşra Şen, Pelin Toros, Şamil Öztürk, Fatih Çöllü, Sevinç İnan, Mehmet İbrahim Tuğlu

“…Phytotherapy has been used for many years due to anticancer and anti-proliferative effects. In this study our purpose was to show the anti-proliferative and…”
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Antiproliferative and Apoptotic Effects of the Medicinal Plants on Breast Cancer Cell Lines by Pınar Kılıçaslan Sönmez, Gülşah Albayrak, Mahmud Özkut, Büşra Şen, Pelin Toros, Şamil Öztürk, Fatih Çöllü, Sevinç İnan, Mehmet İbrahim Tuğlu

“…Inula viscosa, Rubus caesius and Viscum album known as medicinal plants which have therapeutic properties in treatment of various diseases and particularly…”
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EVRİMİN MOLEKÜLER İZLERİ VE KANITLARI by GÜÇLÜ, Selen, ALBAYRAK, Gülşah, DEVECİ, Asuman, EKMEKÇİ, Abdullah

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Halofilik Arkea ve Bakteria Identifikasyonunda Ft-Ir (Fourier Transform-İnfrared Spektroskopisi) Kullanımı by Albayrak, Gülşah

“…Bu çalışmada halofilik prokaryotların FT-IR(Fourier Transform İnfrared Spektroskopisi) ile identifikasyonu amaçlanmıştır. Farklı besiyerleri kullanılarak 12…”
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Evrimin Moleküller İzleri Ve Kanıtları by GÜÇLÜ,Selen, Albayrak,Gülşah, DEVECİ,Asuman, Ekmekçi,Abdullah

“…Evrim, günümüzde teknolojinin sağladığı olanaklarla merakla araştırılmaya devam edilen bir konudur. Evrimsel biyolojik araştırmalar, doğrudan ya da dolaylı…”
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EVRİMİN MOLEKÜLER İZLERİ VE KANITLARI by GÜÇLÜ, Selen; Gazi Üniversitesi, Tıp Fakültesi, Tıbbi Biyoloji ve Genetik Bölümü, ANKARA, TÜRKİYE, ALBAYRAK, Gülşah; Gazi Üniversitesi, Tıp Fakültesi, Tıbbi Biyoloji ve Genetik Bölümü, ANKARA, TÜRKİYE, DEVECİ, Asuman; Gazi Üniversitesi, Tıp Fakültesi, Tıbbi Biyoloji ve Genetik Bölümü, EKMEKÇİ, Abdullah; Gazi Üniversitesi, Tıp Fakültesi, Tıbbi Biyoloji ve Genetik Bölümü, ANKARA, TÜRKİYE

“…Evrim, günümüzde teknolojinin sağladığı olanaklarla merakla araştırılmaya devam edilen bir konudur. Evrimsel biyolojik araştırmalar, doğrudan ya da dolaylı…”
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