The effect of mad honey on testosterone levels of male rats

The effect of mad honey on testosterone levels of male rats

We aimed to investigate the effect of mad honey on sexual performance. In traditional medicine in Turkey, mad honey is used to improve appetite, to heighten mental alertness, to reduce joint pain, to eliminate gastrointestinal system pains and to increase sexual performance. In this experimental ani...

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Published in:Bratislavské lékarské listy Vol. 117; no. 11; pp. 677 - 680
Main Authors: Tatli, O, Karaca, Y, Turkmen, S, Gulgen, G S, Sahin, A, Eryigit, U, Fazli, O, Karaguzel, E, Mentese, A, Orem, A, Cansu, A, Turedi, S, Gunduz, A
Format: Journal Article
Language:English
Published: Slovakia 01-01-2016
Subjects:
Animals
Follicle Stimulating Hormone - blood
Honey - adverse effects
Humans
Luteinizing Hormone - blood
Male
Progesterone - blood
Random Allocation
Rats
Rats, Sprague-Dawley
Sexual Behavior
Testosterone - blood
sexual performance testosterone
mad honey
grayanotoxin
traditional medicine
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Summary:We aimed to investigate the effect of mad honey on sexual performance. In traditional medicine in Turkey, mad honey is used to improve appetite, to heighten mental alertness, to reduce joint pain, to eliminate gastrointestinal system pains and to increase sexual performance. In this experimental animal study eighteen Sprague Dawley male rats were randomized into three groups, a control group, a normal honey group and a mad honey group. Rats in the treatment groups were given a daily dose of 80 mg/kg normal honey or mad honey throughout the 30-day study period. Total testosterone, free testosterone, FSH, LH, estradiol, and progesterone levels were subsequently investigated from blood sera on day 30. Comparison of blood total testosterone levels among the groups revealed significantly higher levels in the mad honey group compared to the normal honey and control groups (p = 0.006, p = 0.00). Free testosterone levels were also significantly higher in the mad honey group than in the normal honey and control groups (p = 0.023, p = 0.01). No statistically significant differences were determined for other hormonal measurements. This study revealed a significant increase in both total and free testosterone levels in mad-honey group (Tab. 1, Fig. 2, Ref. 16).
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ISSN:0006-9248
DOI:10.4149/BLL_2016_130