Bloodstream yeast infections in a university hospital in Northeast Turkey: a 4-year survey

Bloodstream yeast infections in a university hospital in Northeast Turkey: a 4-year survey

This study presents data on species distribution and antifungal susceptibility profiles of Candida bloodstream isolates obtained from a Turkish Tertiary Care Hospital during a 4-year period. All hospitalized patients who had ≥ 1 blood culture positive for yeast during their hospital stay from Januar...

Full description

Saved in:
Bibliographic Details
Published in:Medical mycology (Oxford) Vol. 49; no. 3; pp. 316 - 319
Main Authors: Aydin, Faruk, Bayramoglu, Gulcin, Guler, Necla Cebeci, Kaklikkaya, Nese, Tosun, Ilknur
Format: Journal Article
Language:English
Published: UK Informa Healthcare 01-04-2011
Informa UK Ltd
Subjects:
Adolescent
Adult
Amphotericin B - pharmacology
Antifungal Agents - pharmacology
Candida - drug effects
Candida - isolation & purification
Candidemia - epidemiology
Candidemia - microbiology
Child
Child, Preschool
Drug Resistance, Fungal
Fluconazole - pharmacology
Hospitals, University
Humans
Infant
Infant, Newborn
Microbial Sensitivity Tests
Pyrimidines - pharmacology
Triazoles - pharmacology
Turkey - epidemiology
Voriconazole
Turkey
bloodstream infections
candidemia
antifungal resistance
Candida parapsilosis
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study presents data on species distribution and antifungal susceptibility profiles of Candida bloodstream isolates obtained from a Turkish Tertiary Care Hospital during a 4-year period. All hospitalized patients who had ≥ 1 blood culture positive for yeast during their hospital stay from January 2005 through 2009 were included in this study. All isolates were identified to species level using CHROMagar and ID 32 C. Fluconazole and voriconazole antifungal susceptibility testing was performed using the disk diffusion method according to CLSI M44-A. In vitro activity of amphotericin B was determined by the Etest. Of all 166 yeast isolates, C. albicans was the dominant species (34.3%), followed by Candida parapsilosis (28.9%) and C. tropicalis (8.4%). All of the 48 C. parapsilosis strains were identified as C. parapsilosis sensu stricto. Resistance to fluconazole was more common among C. krusei isolates. Voriconazole resistance was absent. One C. lusitaniae strain showed a high amphotericin MIC (4 μg/ml). Our survey indicated an increase of some non-C. albicans Candida species in our hospital while antifungal resistance was uncommon.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1369-3786
1460-2709
DOI:10.3109/13693786.2010.512023