Search Results - "Gulcan, O."

Dual Monoamine Oxidase and Cholinesterase Inhibitors with Different Heterocyclic Scaffolds by Gulcan, Hayrettin O, Orhan, Ilkay E

“…For the last two decades, there has been research interest on the design of molecules possessing dual inhibitory potential on cholinesterase and monoamine…”
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Chemical and molecular aspects on interactions of galanthamine and its derivatives with cholinesterases by Gulcan, Hayrettin O, Orhan, Ilkay E, Sener, Bilge

“…Dual action of galanthamine as potent cholinesterase inhibitor and nicotinic modulator has attracted a great attention to be used in the treatment of AD…”
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Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and Aβ-Aggregation Inhibitors by Kilic, Burcu, Erdogan, Merve, Gulcan, Hayrettin O, Aksakal, Fatma, Oruklu, Nihan, Bagriacik, Emin U, Dogruer, Deniz S

“…With respect to the increase in the average life expectancy, Alzheimer Disease (AD), the most common form of age-related dementia, has become a major threat to…”
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PP-138: ISOLATED TRICUSPID VALVE REPLACEMENT FOR SEVERE TRICUSPID REGURGITATION: EVALUATION OF 5 PATIENTS by Tunel, H.A, Gulcan, O

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Marginally Designed New Profen Analogues Have the Potential to Inhibit Cyclooxygenase Enzymes by Gülcan, Hayrettin O., Ünlü, Serdar, Dimoglo, Anatoli, Şahin, Yasemin, Esiringu, İlker, Erçetin, Tuba, Öz, Demet, Şahin, Mustafa F.

“…The current structure–activity relationship of profens (i.e., 2‐arylpropionic acid derivatives, a class of non‐steroidal anti‐inflammatory drugs) discusses the…”
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Design, synthesis and biological evaluation of new benzoxazolone/benzothiazolone derivatives as multi-target agents against Alzheimer’s disease by Erdogan, Merve, Kilic, Burcu, Sagkan, Rahsan Ilıkcı, Aksakal, Fatma, Ercetin, Tugba, Gulcan, Hayrettin O., Dogruer, Deniz S.

“…In this study, four series of compounds with benzoxazolone and benzothiazolone cores were designed, synthesized and evaluated as multifunctional agents against…”
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Synthesis, anti‐inflammatory activity, and molecular docking studies of some novel Mannich bases of the 1,3,4‐oxadiazole‐2(3H)‐thione scaffold by Ozyazici, Tugce, Gurdal, Enise E., Orak, Duygu, Sipahi, Hande, Ercetin, Tuba, Gulcan, Hayrettin O., Koksal, Meric

“…A series of novel ibuprofen and salicylic acid‐based 3,5‐disubstituted‐1,3,4‐oxadiazole‐2(3H)‐thione derivatives was synthesized, and they were evaluated as…”
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Design, synthesis, and biological evaluation of new urolithin amides as multitarget agents against Alzheimer's disease by Shukur, Karar T., Ercetin, Tugba, Luise, Chiara, Sippl, Wolfgang, Sirkecioglu, Okan, Ulgen, Mert, Coskun, Goknil P., Yarim, Mine, Gazi, Mustafa, Gulcan, Hayrettin O.

“…A series of urolithin amide (i.e., URO‐4–URO‐10 and THU‐4–THU‐10) derivatives was designed and synthesized, and their chemical structures were confirmed with…”
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Design and synthesis of some new carboxamide and propanamide derivatives bearing phenylpyridazine as a core ring and the investigation of their inhibitory potential on in-vitro acetylcholinesterase and butyrylcholinesterase by Kilic, Burcu, Gulcan, Hayrettin O., Aksakal, Fatma, Ercetin, Tugba, Oruklu, Nihan, Umit Bagriacik, E., Dogruer, Deniz S.

“…[Display omitted] •Carboxamide/propanamide derivatives of phenylpyridazine/biphenyl were synthesized.•Most of the carboxamide derivatives were selective for…”
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230: The effect of thoracic epidural neostigmine on postoperative ileus after abdominal aortic aneurysm surgery by Caliskan, E., Turkoz, A., Sener, M., Bozdogan, N., Gulcan, O., Turkoz, R.

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On-pump/beating-heart myocardial protection for isolated or combined coronary artery bypass grafting in patients with severe left ventricle dysfunction: assessment of myocardial function and clinical outcome by Gulcan, Oner, Turkoz, Riza, Turkoz, Ayda, Caliskan, Esra, Sezgin, Alpay T

“…Myocardial protection in coronary artery bypass grafting (CABG) with severe left ventricular (LV) dysfunction is still a surgical dilemma. Preoperative…”
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The effects of aprotinin and steroids on generation of cytokines during coronary artery surgery by Türköz, Ayda, Çiğli, Ahmet, But, Kadir, Sezgin, Nurzan, Türköz, Rιza, Gülcan, Öner, Ersoy, M.Özcan

“…Objective: To compare the efficacy of aprotinin and methylprednisolone in reducing cardiopulmonary bypass (CPB)–induced cytokine release, to evaluate the…”
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Combined off-pump coronary artery bypass grafting and aorto-bicarotid bypass by Turkoz, R, Gulcan, O, Oguzkurt, L, Tercan, F, Açil, M, Sezgin, A T, Turkoz, A

“…A 63-year-old man with severe coronary artery disease and occlusion of aortic arch branches presented with dizziness, syncope and unstable angina. He underwent…”
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An unusual cause of hemoptysis: ventriculopulmonary fistula by Kuzucu, A, Tandogan, I, Cihan, H B, Gulcan, O, Turkoz, R

“…A 55-year-old man presented with massive hemoptysis following coronary artery bypass grafting and repair of a left ventricular aneurysm. Radiological and…”
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Postoperative delirium and defibrillation by Türköz, Ayda, Türköz, Riza, Gülcan, Oner, Ersoy, Ozcan

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Rupture of the renal artery after cutting balloon angioplasty in a young woman with fibromuscular dysplasia by Oguzkurt, Levent, Tercan, Fahri, Gulcan, Oner, Turkoz, Riza

“…A 24-year-old woman with uncontrollable high blood pressure for 3 months had significant stenosis of the left renal artery caused by fibromuscular dysplasia…”
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Surgical Treatment of a Huge Cavernous Hemangioma Surrounding the Right Coronary Artery by Turkoz, Riza, Gulcan, Oner, Oguzkurt, Levent, Atalay, Hakan, Bolat, Bulent, Sezgin, Alpay

“…Hemangioma of the heart is an extremely rare benign cardiac tumor. A 61-year-old woman presented with a huge hemangioma on the right ventricle. The tumor was…”
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The effect of thoracic epidural neostigmine on postoperative ileus after abdominal aortic aneurysm surgery: 230 by Caliskan, E., Turkoz, A., Sener, M., Bozdogan, N., Gulcan, O., Turkoz, R.

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230. The effect of thoracic epidural neostigmine on postoperative ileus after abdominal aortic aneurysm surgery by Caliskan, E., Turkoz, A., Sener, M., Bozdogan, N., Gulcan, O., Turkoz, R.

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Successful Repair of Iatrogenic Acute Aortic Dissection With Cerebral Malperfusion by Türköz, Rıza, Gulcan, Oner, Oguzkurt, Levent, Calıskan, Esra, Turkoz, Ayda

“…We describe the successful treatment of a patient with iatrogenic acute aortic dissection including cerebral malperfusion as a complication of coronary artery…”
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