Search Results - "Guiwen Ye"

Single-cell RNA sequencing analysis of human bone-marrow-derived mesenchymal stem cells and functional subpopulation identification by Xie, Zhongyu, Yu, Wenhui, Ye, Guiwen, Li, Jinteng, Zheng, Guan, Liu, Wenjie, Lin, Jiajie, Su, Zepeng, Che, Yunshu, Ye, Feng, Zhang, Zhaoqiang, Wang, Peng, Wu, Yanfeng, Shen, Huiyong

“…Mesenchymal stem cells (MSCs) are a common kind of multipotent cell in vivo, but their heterogeneity limits their further applications. To identify MSC…”
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LncRNA‐OG Promotes the Osteogenic Differentiation of Bone Marrow‐Derived Mesenchymal Stem Cells Under the Regulation of hnRNPK by Tang, Su'an, Xie, Zhongyu, Wang, Peng, Li, Jinteng, Wang, Shan, Liu, Wenjie, Li, Ming, Wu, Xiaohua, Su, Hongjun, Cen, Shuizhong, Ye, Guiwen, Zheng, Guan, Wu, Yanfeng, Shen, Huiyong

“…Bone marrow‐derived mesenchymal stem cells (BM‐MSCs) are the main source of osteoblasts in vivo and are widely used in stem cell therapy. Previously, we…”
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TRAF4 positively regulates the osteogenic differentiation of mesenchymal stem cells by acting as an E3 ubiquitin ligase to degrade Smurf2 by Li, Jinteng, Wang, Peng, Xie, Zhongyu, Wang, Shan, Cen, Shuizhong, Li, Ming, Liu, Wenjie, Tang, Su’an, Ye, Guiwen, Zheng, Guan, Su, Hongjun, Ma, Mengjun, Wu, Xiaohua, Wu, Yanfeng, Shen, Huiyong

“…TNF receptor-associated factor 4 (TRAF4), a member of the TRAF family, plays an important role in the embryogenesis and development of the bone system…”
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Abnormal inhibition of osteoclastogenesis by mesenchymal stem cells through the miR-4284/CXCL5 axis in ankylosing spondylitis by Liu, Wenjie, Wang, Peng, Xie, Zhongyu, Wang, Shan, Ma, Mengjun, Li, Jinteng, Li, Ming, Cen, Shuizhong, Tang, Su’an, Zheng, Guan, Ye, Guiwen, Wu, Xiaohua, Wu, Yanfeng, Shen, Huiyong

“…Ankylosing spondylitis (AS) is a common inflammatory autoimmune disease, characterized by pathological osteogenesis. Mesenchymal stem cells (MSCs), as the main…”
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The N 6-methyladenosine demethylase ALKBH5 negatively regulates the osteogenic differentiation of mesenchymal stem cells through PRMT6 by Zhaofeng Li, Peng Wang, Jinteng Li, Zhongyu Xie, Shuizhong Cen, Ming Li, Wenjie Liu, Guiwen Ye, Guan Zheng, Mengjun Ma, Shan Wang, Wenhui Yu, Yanfeng Wu, Huiyong Shen

“…Abstract N 6-methyladenosine (m6A) modification is widespread in messenger RNAs and increasing evidence suggests the crucial roles of m6A in cell…”
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Correction: GAS5 protects against osteoporosis by targeting UPF1/SMAD7 axis in osteoblast differentiation by Li, Ming, Xie, Zhongyu, Li, Jinteng, Lin, Jiajie, Zheng, Guan, Liu, Wenjie, Tang, Su'an, Cen, Shuizhong, Ye, Guiwen, Li, Zhaofeng, Yu, Wenhui, Wang, Peng, Wu, Yanfeng, Shen, Huiyong

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Enhanced osteogenic differentiation of mesenchymal stem cells in ankylosing spondylitis: a study based on a three-dimensional biomimetic environment by Zheng, Guan, Xie, Zhongyu, Wang, Peng, Li, Jinteng, Li, Ming, Cen, Shuizhong, Tang, Su’an, Liu, Wenjie, Ye, Guiwen, Li, Yuxi, Wang, Shan, Wu, Xiaohua, Su, Hongjun, Wu, Yanfeng, Shen, Huiyong

“…The mechanism of pathological osteogenesis in Ankylosing spondylitis (AS) is largely unknown. Our previous studies demonstrated that the imbalance between…”
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TNF-α-mediated m6A modification of ELMO1 triggers directional migration of mesenchymal stem cell in ankylosing spondylitis by Xie, Zhongyu, Yu, Wenhui, Zheng, Guan, Li, Jinteng, Cen, Shuizhong, Ye, Guiwen, Li, Zhaofeng, Liu, Wenjie, Li, Ming, Lin, Jiajie, Su, Zepeng, Che, Yunshu, Ye, Feng, Wang, Peng, Wu, Yanfeng, Shen, Huiyong

“…Ankylosing spondylitis (AS) is a type of rheumatic disease characterized by chronic inflammation and pathological osteogenesis in the entheses. Previously, we…”
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Interleukin-6/interleukin-6 receptor complex promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells by Xie, Zhongyu, Tang, Su'an, Ye, Guiwen, Wang, Peng, Li, Jinteng, Liu, Wenjie, Li, Ming, Wang, Shan, Wu, Xiaohua, Cen, Shuizhong, Zheng, Guan, Ma, Mengjun, Wu, Yanfeng, Shen, Huiyong

“…Interleukin-6 (IL-6) with IL-6 receptor (IL-6R) play an important role in the tissue regeneration in vivo, especially bone metabolism. Bone marrow -derived…”
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ALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression by Ye, Guiwen, Li, Jinteng, Yu, Wenhui, Xie, Zhongyu, Zheng, Guan, Liu, Wenjie, Wang, Shan, Cao, Qian, Lin, Jiajie, Su, Zepeng, Li, Dateng, Che, Yunshu, Fan, Shuai, Wang, Peng, Wu, Yanfeng, Shen, Huiyong

“…Improving health and delaying aging is the focus of medical research. Previous studies have shown that mesenchymal stem cell (MSC) senescence is closely…”
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GAS5 protects against osteoporosis by targeting UPF1/SMAD7 axis in osteoblast differentiation by Li, Ming, Xie, Zhongyu, Li, Jinteng, Lin, Jiajie, Zheng, Guan, Liu, Wenjie, Tang, Su'an, Cen, Shuizhong, Ye, Guiwen, Li, Zhaofeng, Yu, Wenhui, Wang, Peng, Wu, Yanfeng, Shen, Huiyong

“…Osteoporosis is a common systemic skeletal disorder resulting in bone fragility and increased fracture risk. It is still necessary to explore its detailed…”
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CCR9 initiates epithelial-mesenchymal transition by activating Wnt/β-catenin pathways to promote osteosarcoma metastasis by Kong, Haoran, Yu, Wenhui, Chen, Zhuning, Li, Haonan, Ye, Guiwen, Hong, Jiacong, Xie, Zhongyu, Chen, Keng, Wu, Yanfeng, Shen, Huiyong

“…Osteosarcoma (OS) patients with lung metastasis have poor prognoses, and effective therapeutic strategies for delaying or inhibiting the spread of lung…”
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Effects of long-term culture on the biological characteristics and RNA profiles of human bone-marrow-derived mesenchymal stem cells by Wang, Shan, Wang, Ziming, Su, Hongjun, Chen, Fenglei, Ma, Mengjun, Yu, Wenhui, Ye, Guiwen, Cen, Shuizhong, Mi, Rujia, Wu, Xiaohua, Deng, Wen, Feng, Pei, Zeng, Chenying, Shen, Huiyong, Wu, Yanfeng

“…Expansion in vitro prior to mesenchymal stem cells (MSCs) application is a necessary process. Functional and genomic stability has a crucial role in…”
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Targeting macrophage M1 polarization suppression through PCAF inhibition alleviates autoimmune arthritis via synergistic NF-κB and H3K9Ac blockade by Li, Jinteng, Ye, Feng, Xu, Xiaojun, Xu, Peitao, Wang, Peng, Zheng, Guan, Ye, Guiwen, Yu, Wenhui, Su, Zepeng, Lin, Jiajie, Che, Yunshu, Liu, Zhidong, Feng, Pei, Cao, Qian, Li, Dateng, Xie, Zhongyu, Wu, Yanfeng, Shen, Huiyong

“…Abstract Sustained inflammatory invasion leads to joint damage and progressive disability in several autoimmune rheumatic diseases. In recent decades,…”
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Osteogenic differentiation of mesenchymal stem cells promotes c-Jun-dependent secretion of interleukin 8 and mediates the migration and differentiation of CD4 + T cells by Ye, Feng, Li, Jinteng, Xu, Peitao, Xie, Zhongyu, Zheng, Guan, Liu, Wenjie, Ye, Guiwen, Yu, Wenhui, Lin, Jiajie, Su, Zepeng, Che, Yunshu, Zhang, Zhaoqiang, Wang, Peng, Wu, Yanfeng, Shen, Huiyong

“…The immune system and the skeletal system have complex interactions in the bone marrow and even in the joints, which has promoted the development of the…”
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A novel Anti-ROS osteoblast-specific delivery system for ankylosing spondylitis treatment via suppression of both inflammation and pathological new bone formation by Zheng, Guan, Peng, Xiaoshuai, Zhang, Yunhui, Wang, Peng, Xie, Zhongyu, Li, Jinteng, Liu, Wenjie, Ye, Guiwen, Lin, Yucong, Li, Guojian, Liu, Huatao, Zeng, Chenying, Li, Lihua, Wu, Yanfeng, Shen, Huiyong

“…Ankylosing spondylitis (AS) is a common rheumatic disorder distinguished by chronic inflammation and heterotopic ossification at local entheses sites…”
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LncRNA MRF drives the regulatory function on monocyte recruitment and polarization through HNRNPD-MCP1 axis in mesenchymal stem cells by Lin, Jiajie, Xie, Zhongyu, Zhang, Zhaoqiang, Li, Ming, Ye, Guiwen, Yu, Wenhui, Li, Jinteng, Ye, Feng, Su, Zepeng, Che, Yunshu, Xu, Peitao, Zeng, Chenying, Wang, Peng, Wu, Yanfeng, Shen, Huiyong

“…Abstract Background Mesenchymal stem cells (MSCs) exhibit two bidirectional immunomodulatory abilities: proinflammatory and anti-inflammatory regulatory…”
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TRAF4 acts as a fate checkpoint to regulate the adipogenic differentiation of MSCs by activating PKM2 by Cen, Shuizhong, Li, Jinteng, Cai, Zhaopeng, Pan, Yiqian, Sun, Zehang, Li, Zhaofeng, Ye, Guiwen, Zheng, Guan, Li, Ming, Liu, Wenjie, Yu, Wenhui, Wang, Shan, Xie, Zhongyu, Wang, Peng, Shen, Huiyong

“…Mesenchymal stem cells (MSCs) selectively differentiate into adipocytes or osteoblasts, and several molecules control the fate determination of MSCs…”
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Correction to: CCR9 initiates epithelial-mesenchymal transition by activating Wnt/β-catenin pathways to promote osteosarcoma metastasis by Kong, Haoran, Yu, Wenhui, Chen, Zhuning, Li, Haonan, Ye, Guiwen, Hong, Jiacong, Xie, Zhongyu, Chen, Keng, Wu, Yanfeng, Shen, Huiyong

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Correction: Targeting macrophage M1 polarization suppression through PCAF inhibition alleviates autoimmune arthritis via synergistic NF-κB and H3K9Ac blockade by Li, Jinteng, Ye, Feng, Xu, Xiaojun, Xu, Peitao, Wang, Peng, Zheng, Guan, Ye, Guiwen, Yu, Wenhui, Su, Zepeng, Lin, Jiajie, Che, Yunshu, Liu, Zhidong, Feng, Pei, Cao, Qian, Li, Dateng, Xie, Zhongyu, Wu, Yanfeng, Shen, Huiyong

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