Search Results - "Guirguis, Emilia"
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From PDE3B to the regulation of energy homeostasis
Published in Current opinion in pharmacology (01-12-2011)“…Highlights ► Acute hormonal regulation of PDE3B involves reversible protein phosphorylation and protein complex formation at different subcellular locations. ►…”
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White to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function
Published in Scientific reports (13-01-2017)“…Understanding mechanisms by which a population of beige adipocytes is increased in white adipose tissue (WAT) reflects a potential strategy in the fight…”
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Potential Role of PDE3B in Acquisition of Brown Fat Characteristic by White Adipose Tissue in Mice
Published in The FASEB journal (01-04-2011)“…Cyclic nucleotide phosphodiesterase 3B (PDE3B) regulates energy metabolism. PDE3B knockout (KO) mice in SvJ129 background have less white adipose tissue (WAT)…”
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A Role for Phosphodiesterase 3B in Acquisition of Brown Fat Characteristics by White Adipose Tissue in Male Mice
Published in Endocrinology (Philadelphia) (01-09-2013)“…Obesity is linked to various diseases, including insulin resistance, diabetes, and cardiovascular disorders. The idea of inducing white adipose tissue (WAT) to…”
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Regulation of the pro-inflammatory cytokine osteopontin by GIP in adipocytes – A role for the transcription factor NFAT and phosphodiesterase 3B
Published in Biochemical and biophysical research communications (07-09-2012)“…► GIP stimulates lipogenesis and osteopontin expression in primary adipocytes. ► GIP-induced osteopontin expression is NFAT-dependent. ► Osteopontin expression…”
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Characterization of insulin sensitivity and signaling in adipocytes from congenic rats
Published in Diabetologia Croatica (01-09-2012)“…Genetic analysis of the diabetic Goto-Kakizaki rat has identified a major diabetes quantitative trait locus (Niddml). Congenic strains generated for two…”
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