Search Results - "Guirguis, Emilia"

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  1. 1

    From PDE3B to the regulation of energy homeostasis by Degerman, Eva, Ahmad, Faiyaz, Chung, Youn Wook, Guirguis, Emilia, Omar, Bilal, Stenson, Lena, Manganiello, Vincent

    Published in Current opinion in pharmacology (01-12-2011)
    “…Highlights ► Acute hormonal regulation of PDE3B involves reversible protein phosphorylation and protein complex formation at different subcellular locations. ►…”
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    Journal Article
  2. 2

    White to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function by Chung, Youn Wook, Ahmad, Faiyaz, Tang, Yan, Hockman, Steven C., Kee, Hyun Jung, Berger, Karin, Guirguis, Emilia, Choi, Young Hun, Schimel, Dan M., Aponte, Angel M., Park, Sunhee, Degerman, Eva, Manganiello, Vincent C.

    Published in Scientific reports (13-01-2017)
    “…Understanding mechanisms by which a population of beige adipocytes is increased in white adipose tissue (WAT) reflects a potential strategy in the fight…”
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  3. 3

    Potential Role of PDE3B in Acquisition of Brown Fat Characteristic by White Adipose Tissue in Mice by Guirguis, Emilia, Hockman, Steven, Manganiello, Vincent

    Published in The FASEB journal (01-04-2011)
    “…Cyclic nucleotide phosphodiesterase 3B (PDE3B) regulates energy metabolism. PDE3B knockout (KO) mice in SvJ129 background have less white adipose tissue (WAT)…”
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  4. 4

    A Role for Phosphodiesterase 3B in Acquisition of Brown Fat Characteristics by White Adipose Tissue in Male Mice by Guirguis, Emilia, Hockman, Steven, Chung, Youn Wook, Ahmad, Faiyaz, Gavrilova, Oksana, Raghavachari, Nalini, Yang, Yanqin, Niu, Gang, Chen, Xiaoyuan, Yu, Zu Xi, Liu, Shiwei, Degerman, Eva, Manganiello, Vincent

    Published in Endocrinology (Philadelphia) (01-09-2013)
    “…Obesity is linked to various diseases, including insulin resistance, diabetes, and cardiovascular disorders. The idea of inducing white adipose tissue (WAT) to…”
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  5. 5

    Regulation of the pro-inflammatory cytokine osteopontin by GIP in adipocytes – A role for the transcription factor NFAT and phosphodiesterase 3B by Omar, Bilal, Banke, Elin, Guirguis, Emilia, Åkesson, Lina, Manganiello, Vincent, Lyssenko, Valeriya, Groop, Leif, Gomez, Maria F., Degerman, Eva

    “…► GIP stimulates lipogenesis and osteopontin expression in primary adipocytes. ► GIP-induced osteopontin expression is NFAT-dependent. ► Osteopontin expression…”
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  6. 6

    Characterization of insulin sensitivity and signaling in adipocytes from congenic rats by Guirguis, Emilia, Berger, Karin, Luthman, Holger, Degerman, Eva

    Published in Diabetologia Croatica (01-09-2012)
    “…Genetic analysis of the diabetic Goto-Kakizaki rat has identified a major diabetes quantitative trait locus (Niddml). Congenic strains generated for two…”
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