Search Results - "Guiraldelli, Michel F"
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Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes
Published in PLoS genetics (01-06-2012)“…Recent studies in simple model organisms have shown that centromere pairing is important for ensuring high-fidelity meiotic chromosome segregation. However,…”
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SHOC1 is a ERCC4-(HhH)2-like protein, integral to the formation of crossover recombination intermediates during mammalian meiosis
Published in PLoS genetics (01-05-2018)“…Chromosome segregation errors during meiosis result in the formation of aneuploid gametes and are the leading cause of pregnancy loss and birth defects in…”
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3
Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis
Published in PLoS genetics (01-03-2013)“…Faithful chromosome segregation during meiosis requires that homologous chromosomes associate and recombine. Chiasmata, the cytological manifestation of…”
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4
Small interfering RNA screen for phosphatases involved in IgE-mediated mast cell degranulation
Published in The Journal of immunology (1950) (15-06-2010)“…Mast cells play pivotal roles in the initiation of the allergic response. To gain an understanding of the functions played by phosphatases in IgE-mediated mast…”
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The chromatin-remodeling subunit Baf200 promotes homology-directed DNA repair and regulates distinct chromatin-remodeling complexes
Published in The Journal of biological chemistry (19-05-2017)“…The efficiency and type of pathway chosen to repair DNA double-strand breaks (DSBs) are critically influenced by the nucleosome packaging and the chromatin…”
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Genome instability and embryonic developmental defects in RMI1 deficient mice
Published in DNA repair (01-10-2013)“…•Deletion of Rmi1 in mice results in embryonic developmental defects.•Rmi1hy/hy MEFs exhibit genome instability and severely impaired cell proliferation.•RMI1…”
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Solution Structure and DNA-binding Properties of the Winged Helix Domain of the Meiotic Recombination HOP2 Protein
Published in The Journal of biological chemistry (23-05-2014)“…The HOP2 protein is required for efficient double-strand break repair which ensures the proper synapsis of homologous chromosomes and normal meiotic…”
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The low affinity IgG receptor FcγRIIB contributes to the binding of the mast cell specific antibody, mAb BGD6
Published in Molecular immunology (01-04-2008)“…The mast cell specific monoclonal antibody, mAb BGD6, is a mast cell lineage marker [Jamur, M.C., Grodzki, A.C., Berenstein, E.H., Hamawy, M.M., Siraganian,…”
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SHOC1 is a ERCC4-.sub.2-like protein, integral to the formation of crossover recombination intermediates during mammalian meiosis
Published in PLoS genetics (09-05-2018)“…Chromosome segregation errors during meiosis result in the formation of aneuploid gametes and are the leading cause of pregnancy loss and birth defects in…”
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10
SHOC1 is a ERCC4
Published in PLoS genetics (09-05-2018)“…Chromosome segregation errors during meiosis result in the formation of aneuploid gametes and are the leading cause of pregnancy loss and birth defects in…”
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11
Abstract 4404: Identification of small molecules that inhibit miR-21 activity in breast cancer
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract In cancer, microRNA (miR) dysregulation can lead to tumor development, invasion and metastasis. miRs are small single-stranded non-coding RNAs that…”
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Mouse HFM1/Mer3 Is Required for Crossover Formation and Complete Synapsis of Homologous Chromosomes during Meiosis: e1003383
Published in PLoS genetics (01-03-2013)“…Faithful chromosome segregation during meiosis requires that homologous chromosomes associate and recombine. Chiasmata, the cytological manifestation of…”
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A Monoclonal Antibody that inhibits IgE binding to the High affinity IgE receptor recognizes a glycolipid (36.11)
Published in The Journal of immunology (1950) (01-04-2009)“…Abstract The mAb BD6 is a monoclonal IgM that binds to the surface of RBL-2H3 cells and inhibits the binding of IgE to FcεRI, without reacting with this…”
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