Search Results - "Guinn, M"

Landscape controls on the timing of spring, autumn, and growing season length in mid-Atlantic forests by Elmore, Andrew J., Guinn, Steven M., Minsley, Burke J., Richardson, Andrew D.

“…The timing of spring leaf development, trajectories of summer leaf area, and the timing of autumn senescence have profound impacts to the water, carbon, and…”
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Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis by Jansen, Robert S., Mandyoli, Lungelo, Hughes, Ryan, Wakabayashi, Shoko, Pinkham, Jessica T., Selbach, Bruna, Guinn, Kristine M., Rubin, Eric J., Sacchettini, James C., Rhee, Kyu Y.

“…Gene rv3722c of Mycobacterium tuberculosis is essential for in vitro growth, and encodes a putative pyridoxal phosphate-binding protein of unknown function…”
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Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis by Ioerger, Thomas R, O'Malley, Theresa, Liao, Reiling, Guinn, Kristine M, Hickey, Mark J, Mohaideen, Nilofar, Murphy, Kenan C, Boshoff, Helena I M, Mizrahi, Valerie, Rubin, Eric J, Sassetti, Christopher M, Barry, 3rd, Clifton E, Sherman, David R, Parish, Tanya, Sacchettini, James C

“…Identification of new drug targets is vital for the advancement of drug discovery against Mycobacterium tuberculosis, especially given the increase of…”
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The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection by Lin, Philana Ling, Dietrich, Jes, Tan, Esterlina, Abalos, Rodolfo M, Burgos, Jasmin, Bigbee, Carolyn, Bigbee, Matthew, Milk, Leslie, Gideon, Hannah P, Rodgers, Mark, Cochran, Catherine, Guinn, Kristi M, Sherman, David R, Klein, Edwin, Janssen, Christopher, Flynn, JoAnne L, Andersen, Peter

“…It is estimated that one-third of the world's population is infected with Mycobacterium tuberculosis. Infection typically remains latent, but it can reactivate…”
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Deprotection of N‑Boc Groups under Continuous-Flow High-Temperature Conditions by Li, Bryan, Li, Ruizhi, Dorff, Peter, McWilliams, J. Christopher, Guinn, Robert M, Guinness, Steven M, Han, Lu, Wang, Ke, Yu, Shu

“…The scope of thermolytic, N-Boc deprotection was studied on 26 compounds from the Pfizer compound library, representing a diverse set of structural moieties…”
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Towards control of cellular decision-making networks in the epithelial-to-mesenchymal transition by Gómez Tejeda Zañudo, Jorge, Guinn, M Tyler, Farquhar, Kevin, Szenk, Mariola, Steinway, Steven N, Balázsi, Gábor, Albert, Réka

“…We present the epithelial-to-mesenchymal transition (EMT) from two perspectives: experimental/technological and theoretical. We review the state of the current…”
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Tuberculosis: Just the FAQs by Guinn, Kristine M, Rubin, Eric J

“…Tuberculosis is responsible for more deaths worldwide than any other infectious disease. For anyone looking to learn more about this persistent public health…”
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The association between lower Hounsfield units of the upper instrumented vertebra and proximal junctional kyphosis in adult spinal deformity surgery with a minimum 2-year follow-up by Duan, Ping-Guo, Mummaneni, Praveen V., Rivera, Joshua, Guinn, Jeremy M. V., Wang, Minghao, Xi, Zhuo, Li, Bo, Wu, Hao-Hua, Ames, Christopher P., Burch, Shane, Berven, Sigurd H., Chou, Dean

“…OBJECTIVEPatients undergoing long-segment fusions from the lower thoracic (LT) spine to the sacrum for adult spinal deformity (ASD) correction are at risk for…”
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Individual RD1‐region genes are required for export of ESAT‐6/CFP‐10 and for virulence of Mycobacterium tuberculosis by Guinn, Kristi M., Hickey, Mark J., Mathur, Sanjeev K., Zakel, Kelly L., Grotzke, Jeff E., Lewinsohn, David M., Smith, Sherilyn, Sherman, David R.

“…Summary The RD1 genomic region is present in virulent strains of Mycobacterium tuberculosis (MTB), missing from the vaccine strain M. bovis BCG, and its…”
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Is the Goutallier grade of multifidus fat infiltration associated with adjacent-segment degeneration after lumbar spinal fusion? by Duan, Ping-Guo, Mummaneni, Praveen V, Guinn, Jeremy M V, Rivera, Joshua, Berven, Sigurd H, Chou, Dean

“…The aim of this study was to investigate whether fat infiltration of the lumbar multifidus (LM) muscle affects revision surgery rates for adjacent-segment…”
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Deletion of RD1 from Mycobacterium tuberculosis Mimics Bacille Calmette-Guérin Attenuation by Lewis, Kaeryn N., Liao, Reiling, Guinn, Kristi M., Hickey, Mark J., Smith, Sherilyn, Behr, Marcel A., Sherman, David R.

“…The tuberculosis (TB) vaccine bacille Calmette-Guérin (BCG) is a live attenuated organism, but the mutation responsible for its attenuation has never been…”
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Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis by Park, Heui‐Dong, Guinn, Kristi M., Harrell, Maria I., Liao, Reiling, Voskuil, Martin I., Tompa, Martin, Schoolnik, Gary K., Sherman, David R.

“…Summary Unlike many pathogens that are overtly harmful to their hosts, Mycobacterium tuberculosis can persist for years within humans in a clinically latent…”
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Continental scale variability of foliar nitrogen and carbon isotopes in Populus balsamifera and their relationships with climate by Elmore, Andrew J., Craine, Joseph M., Nelson, David M., Guinn, Steven M.

“…Variation across climate gradients in the isotopic composition of nitrogen (N) and carbon (C) in foliar tissues has the potential to reveal ecological…”
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Dasymetric population mapping based on US census data and 30-m gridded estimates of impervious surface by Swanwick, Rachel H., Read, Quentin D., Guinn, Steven M., Williamson, Matthew A., Hondula, Kelly L., Elmore, Andrew J.

“…Assessment of socio-environmental problems and the search for solutions often require intersecting geospatial data on environmental factors and human…”
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Potential stream density in Mid-Atlantic US watersheds by Elmore, Andrew J, Julian, Jason P, Guinn, Steven M, Fitzpatrick, Matthew C

“…Stream network density exerts a strong influence on ecohydrologic processes in watersheds, yet existing stream maps fail to capture most headwater streams and…”
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Metabolic and bactericidal effects of targeted suppression of NadD and NadE enzymes in mycobacteria by Rodionova, Irina A, Schuster, Brian M, Guinn, Kristine M, Sorci, Leonardo, Scott, David A, Li, Xiaoqing, Kheterpal, Indu, Shoen, Carolyn, Cynamon, Michael, Locher, Christopher, Rubin, Eric J, Osterman, Andrei L

“…Mycobacterium tuberculosis remains a major cause of death due to the lack of treatment accessibility, HIV coinfection, and drug resistance. Development of new…”
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Implementing New Approaches to Tuberculosis Control by Guinn, Kristine M, Rubin, Eric J

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Modeled Tradeoffs between Developed Land Protection and Tidal Habitat Maintenance during Rising Sea Levels by Cadol, Daniel, Elmore, Andrew J, Guinn, Steven M, Engelhardt, Katharina A M, Sanders, Geoffrey

“…Tidal habitats host a diversity of species and provide hydrological services such as shoreline protection and nutrient attenuation. Accretion of sediment and…”
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Leveraging the NEON Airborne Observation Platform for socio‐environmental systems research by Ordway, Elsa M., Elmore, Andrew J., Kolstoe, Sonja, Quinn, John E., Swanwick, Rachel, Cattau, Megan, Taillie, Dylan, Guinn, Steven M., Chadwick, K. Dana, Atkins, Jeff W., Blake, Rachael E., Chapman, Melissa, Cobourn, Kelly, Goulden, Tristan, Helmus, Matthew R., Hondula, Kelly, Hritz, Carrie, Jensen, Jennifer, Julian, Jason P., Kuwayama, Yusuke, Lulla, Vijay, O’Leary, Donal, Nelson, Donald R., Ocón, Jonathan P., Pau, Stephanie, Ponce‐Campos, Guillermo E., Portillo‐Quintero, Carlos, Pricope, Narcisa G., Rivero, Rosanna G., Schneider, Laura, Steele, Meredith, Tulbure, Mirela G., Williamson, Matthew A., Wilson, Cyril

“…During the 21st century, human–environment interactions will increasingly expose both systems to risks, but also yield opportunities for improvement as we gain…”
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Posterior Displacement of L1 May be a Risk Factor for Proximal Junctional Kyphosis After Adult Spinal Deformity Correction by Xi, Zhuo, Duan, Ping-Guo, Mummaneni, Praveen V., Liu, Jinping, Guinn, Jeremy M.V., Wang, Minghao, Li, Bo, Wu, Hao-Hua, Rivera, Joshua, Burch, Shane, Berven, Sigurd H., Chou, Dean

“…Study Design: Retrospective cohort study. Objective: Overcorrection in adult spinal deformity (ASD) surgery may lead to proximal junctional kyphosis (PJK)…”
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