Search Results - "Guindy, M."

Ameliorating effects of adropin on letrozole‐induced polycystic ovary syndrome via regulating steroidogenesis and the microbiota inflammatory axis in rats by Rizk, Fatma H., El Saadany, Amira A., Elshamy, Amira Mostafa, Abd Ellatif, Rasha A., El‐Guindy, Dina M., Helal, Duaa S., Hamama, Mohamed G., El‐Sharnoby, Jehan Abd El‐Hameed, Abdel Ghafar, Muhammad T., Faheem, Heba

“…Growing evidence supports the role of gut microbiota in chronic inflammation, insulin resistance (IR) and sex hormone production in polycystic ovary syndrome…”
Get full text

Potential role of tumor‐associated macrophages and CD163/CD68 ratio in mycosis fungoides and Sézary syndrome in correlation with serum sCD163 and CCL22 by El‐Guindy, Dina M., Elgarhy, Lamia H., Elkholy, Rasha A., Ali, Dina A., Helal, Duaa S.

“…Currently, there are no curative treatment options for mycosis fungoides (MF) and Sézary syndrome (SS) other than stem cell transplant. Understanding the…”
Get full text

EGYVIR: An immunomodulatory herbal extract with potent antiviral activity against SARS-CoV-2 by Roshdy, Wael H, Rashed, Helmy A, Kandeil, Ahmed, Mostafa, Ahmed, Moatasim, Yassmin, Kutkat, Omnia, Abo Shama, Noura M, Gomaa, Mokhtar R, El-Sayed, Ibrahim H, El Guindy, Nancy M, Naguib, Amal, Kayali, Ghazi, Ali, Mohamed A

“…Due to the challenges for developing vaccines in devastating pandemic situations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), developing…”
Get full text

Immunohistochemical based molecular subtypes of muscle-invasive bladder cancer: association with HER2 and EGFR alterations, neoadjuvant chemotherapy response and survival by Helal, Duaa S, Darwish, Sara A, Awad, Radwa A, Ali, Dina A, El-Guindy, Dina M

“…Muscle-invasive bladder cancers (MIBCs) is a group of molecularly heterogonous diseases that could be stratified into subtypes with distinct clinical courses…”
Get full text

Pathologic assessment of tumor-associated macrophages and their histologic localization in invasive breast carcinoma by Mwafy, Shorouk E, El-Guindy, Dina M

“…Tumor-associated macrophages (TAMs) are important in regulating cross-talk between tumor cells and tumor microenvironment. TAMs are involved in multiple steps…”
Get full text

Oct4 expression in gastric carcinoma: association with tumor proliferation, angiogenesis and survival by El-Guindy, Dina M, Wasfy, Rania E, Abdel Ghafar, Muhammad T, Ali, Dina A, Elkady, Asmaa M

“…Background Octamer-binding transcription factor 4 (Oct4) is a transcription factor that has an important role in stem cell differentiation and self-renewal…”
Get full text

Chemotherapy may eradicate ductal carcinoma in situ (DCIS) but not the associated microcalcifications by Goldberg, H, Zandbank, J, Kent, V, Leonov-Polak, M, Livoff, A, Chernihovsky, A, Guindy, M, Evron, E

“…Abstract Introduction We studied the effect of neoadjuvant chemotherapy (NAC) ± trastuzumab on the ductal carcinoma in situ (DCIS) component in patients with…”
Get full text

Coding-Complete Genome Sequences of Two SARS-CoV-2 Isolates from Egypt by Kandeil, Ahmed, Mostafa, Ahmed, El-Shesheny, Rabeh, Shehata, Mahmoud, Roshdy, Wael H, Ahmed, Shymaa Showky, Gomaa, Mokhtar, Taweel, Ahmed El, Kayed, Ahmed E, Mahmoud, Sara H, Moatasim, Yassmin, Kutkat, Omnia, Kamel, Mina Nabil, Mahrous, Noura, Sayes, Mohamed El, Guindy, Nancy M El, Naguib, Amal, Ali, Mohamed A

“…This report announces the complete genome sequences of two severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolates detected in Egypt. The…”
Get full text

Quantitative biomarkers for liver metastases: comparison of MRI diffusion-weighted imaging heterogeneity index and fluorine-18-fluoro-deoxyglucose standardised uptake value in hybrid PET/MR by Stein, D., Goldberg, N., Domachevsky, L., Bernstine, H., Nidam, M., Abadi-Korek, I., Guindy, M., Sosna, J., Groshar, D.

“…To investigate the ability of apparent diffusion coefficient (ADC) heterogeneity index to discriminate liver metastases (LM) from normal-appearing liver (NAL)…”
Get full text

Comparison of CT and adjusted MRI for evaluating paranasal sinuses surgical key landmarks by Landsberg, R., Schneider, S., Masalha, M., Margulis, A., Guindy, M., Luckman, J.

“…Background: Sinus CT is the imaging technique of choice for planning endoscopic sinus surgery (ESS). Although MRI has a better soft tissue demonstration, it is…”
Get full text

Programmed cell death ligand-1 (PD-L1) expression combined with CD8 tumor infiltrating lymphocytes density in non-small cell lung cancer patients by El-Guindy, Dina M., Helal, Duaa S., Sabry, Nesreen M., Abo El-Nasr, Mohamed

“…Cancer immunotherapy targeting programmed cell death-1/programmed cell death ligand-1 (PD-1/PD-L1) pathway has shown promising results in treatment of…”
Get full text

The Prognostic Significance of MACC1 Expression in Breast Cancer and Its Relationship to Immune Cells in the Tumor Microenvironment and Patient Survival by Ali, Dina A, El-Guindy, Dina M, Elrashidy, Mohamed A, Sabry, Nesreen M, Kabel, Ahmed M, Gaber, Rasha A, Ibrahim, Rowida R, Samy, Sara M, Shalaby, Marwa M, Salama, Samir A, Abdelhai, Dina

“…Breast cancer (BC) is one of the most prevalent malignancies among females worldwide. Globally, distant metastases were reported to be responsible for a large…”
Get full text

Maspin expression and subcellular localization in invasive ductal carcinoma of the breast: Prognostic significance and relation to microvessel density by Helal, Duaa S., El-Guindy, Dina M.

“…Maspin (Mammary serine protease inhibitor) is a tumor suppressor serine. Its clinical significance and role in breast carcinoma are contradictory and…”
Get full text

Cytotoxic T lymphocyte antigen-4 gene polymorphism in systemic lupus erythematosus Egyptian patients by El Guindy, Nancy M., AbdEl Ghaffar, Heba A., El Refai, Rasha M., El Hawary, Rabab E.

“…The human cytotoxic T lymphocyte antigen-4 (CTLA-4) gene has been confirmed to be associated with several autoimmune diseases. In this study, we investigated…”
Get full text

Moxidectin versus Ivermectin in the prevention and treatment of acute and chronic experimental trichinellosis by Elmehy, Dalia A., Gamea, Ghada A., El-Guindy, Dina M., Tahoon, Dina M., Elkholy, Reem A., Zoghroban, Hager S.

“…The limited activity of the traditional medications against T. spiralis encysted larvae handicaps complete cure of trichinellosis till now due to decreased…”
Get full text

The effects of L-citrulline adjunctive treatment of Toxoplasma gondii RH strain infection in a mouse model by Saad, Abeer E., Zoghroban, Hager S., Ghanem, Heba B., El-Guindy, Dina M., Younis, Salwa S.

“…•L-citrulline supplementation is effective against acute toxoplasmosis, mainly when combined with sulfamethoxazole-trimethoprim.•The combined treatment…”
Get full text

Ulinastatin ameliorated streptozotocin-induced diabetic nephropathy: Potential effects via modulating the components of gut-kidney axis and restoring mitochondrial homeostasis by Rizk, Fatma H., El Saadany, Amira A., Atef, Marwa Mohamed, Abd-Ellatif, Rania Nagi, El-Guindy, Dina M., Abdel Ghafar, Muhammad T., Shalaby, Marwa M., Hafez, Yasser Mostafa, Mashal, Shaimaa Samir Amin, Basha, Eman H., Faheem, Heba, Barhoma, Ramez Abd-Elmoneim

“…Growing evidence supports the role of the gut-kidney axis and persistent mitochondrial dysfunction in the pathogenesis of diabetic nephropathy (DN)…”
Get full text

Hypoxia-induced autophagy in triple negative breast cancer: association with prognostic variables, patients’ survival and response to neoadjuvant chemotherapy by El-Guindy, Dina M., Ibrahim, Fatma MKh, Ali, Dina A., El-Horany, Hemat El-Sayed, Sabry, Nesreen M., Elkholy, Rasha A., Mansour, Wael, Helal, Duaa S.

“…Autophagy is a cellular response to diverse stresses within tumor microenvironment (TME) such as hypoxia. It enhances cell survival and triggers resistance to…”
Get full text

Can Serum Tenascin-C Be Used as a Marker of Inflammation in Patients with Dilated Cardiomyopathy? by Kotby, Alyaa A., Abdel Aziz, Manal M., El Guindy, Waleed M., Moneer, Amira N.

“…Background. Tenascin-C (TN-C) is an extracellular matrix glycoprotein that appears at sites of inflammation in cardiac pathologies. Aim of the Work. To…”
Get full text

MicroRNA Let-7a association with glycolysis-induced autophagy in locally advanced gastric cancer: Their role in prognosis and FLOT chemotherapy resistance by Helal, Duaa S., Sabry, Nesreen, Ali, Dina A., AboElnasr, Sahbaa M., Abdel Ghafar, Muhammad T., Sarhan, Mohamed Elsayed, Sabry, Mohab, El-Guindy, Dina M.

“…Locally advanced gastric cancer (LAGC) still poses a clinical challenge despite multimodality treatment due to multidrug resistance (MDR). Recently, research…”
Get full text