Search Results - "Guimarães, Gabriela Rapozo"
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Hallmarks of Aging in Macrophages: Consequences to Skin Inflammaging
Published in Cells (Basel, Switzerland) (26-05-2021)“…The skin is our largest organ and the outermost protective barrier. Its aging reflects both intrinsic and extrinsic processes resulting from the constant…”
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Dynamic changes in B cell subpopulations in response to triple-negative breast cancer development
Published in Scientific reports (21-05-2024)“…Despite presenting a worse prognosis and being associated with highly aggressive tumors, triple-negative breast cancer (TNBC) is characterized by the higher…”
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Impaired expression of serine/arginine protein kinase 2 (SRPK2) affects melanoma progression
Published in Frontiers in genetics (23-09-2022)“…Melanoma is one of the most aggressive tumors, and its lethality is associated with the ability of malignant cells to migrate and invade surrounding tissues to…”
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The SRPK inhibitor N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl) isonicotinamide (SRPIN340) increases the immune response against metastatic melanoma in mice
Published in Biochemical pharmacology (01-09-2022)“…[Display omitted] Cancers have a strong relationship with immune cells in their microenvironment, which significantly influences tumor proliferation and…”
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Single-cell resolution characterization of myeloid-derived cell states with implication in cancer outcome
Published in Nature communications (07-07-2024)“…Tumor-associated myeloid-derived cells (MDCs) significantly impact cancer prognosis and treatment responses due to their remarkable plasticity and tumorigenic…”
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Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models
Published in npj aging (22-05-2023)“…Cellular senescence is known to play a role in age-related skin function deterioration which potentially influences longevity. Here, a two-step phenotypic…”
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Author Correction: Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models
Published in npj aging (15-02-2024)Get full text
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