Search Results - "Guimarães, Andrea Grabe"

Acute toxicity and antitumor potential of 1,3,4‐trisubstituted‐1,2,3‐triazole dhmtAc‐loaded liposomes on a triple‐negative breast cancer model by Ramos, Jonas P., Abdel‐Salam, Mostafa A. L., Nobre, Daniel A. B., Glanzmann, Nicolas, de Souza, Camila P., Leite, Elaine A., de Abreu Teles, Pedro P., Barbosa, Alan S., Barcelos, Luciola S., dos Reis, Diego C., Cassali, Geovanni D., de Lima, Maria E., de Castro, Quênia J. T., Grabe‐Guimarães, Andrea, da Silva, Adilson D., de Souza‐Fagundes, Elaine M.

“…For the first time, compounds developed from the 1,2,3‐triazole scaffold were evaluated as novel drugs to treat triple‐negative breast cancer (TNBC). Four…”
Get full text

Effects of physical exercise combined with captopril or losartan on left ventricular hypertrophy of hypertensive rats by Tomaz de Castro, Quênia Janaína, Araujo, Carolina Morais, Watai, Patrícia Yoshie, de Castro e Silva, Samara Stéfani, de Lima, Wanderson Geraldo, Becker, Lenice Kappes, Locatelli, Jamille, Guimarães, Homero Nogueira, Grabe-Guimarães, Andrea

“…Background: Left ventricular hypertrophy (LVH) is an endpoint of hypertensive cardiac alterations. Renin-angiotensin-aldosterone system (RAAS) blockers are…”
Get full text

Polylactide Nanocapsules Attenuate Adverse Cardiac Cellular Effects of Lyso-7, a Pan-PPAR Agonist/Anti-Inflammatory New Thiazolidinedione by Garcia, Giani M., Roy, Jérôme, Pitta, Ivan R., Abdalla, Dulcinéia S. P., Grabe-Guimarães, Andrea, Mosqueira, Vanessa C. F., Richard, Sylvain

“…Lyso-7 is a novel synthetic thiazolidinedione, which is a receptor (pan) agonist of PPAR α,β/δ,γ with anti-inflammatory activity. We investigated the…”
Get full text

Not everything is condemned by COVID-19 by JÚnior, Waldemar DE Paula, Neto, Francisco F DE Lima, Grabe-GuimarÃes, Andrea

“…The increase in the number of studies related to the health of university students has attracted attention at the time of COVID-19. This initiative contributes…”
Get full text

Anti-Inflammatory Sesquiterpene Lactones from Lychnophora trichocarpha Spreng. (Brazilian Arnica) by Ferrari, Fernanda C., Ferreira, Leidiane C., Souza, Maíra R., Grabe-Guimarães, Andrea, Paula, Carmen A., Rezende, Simone A., Saúde-Guimarães, Dênia A.

“…The aerial parts of Lychnophora trichocarpha Spreng. (Asteraceae) are used macerated in water or ethanol to treat inflammation, pain, rheumatism, contusions,…”
Get full text

Mechanisms of artemether toxicity on single cardiomyocytes and protective effect of nanoencapsulation by Moreira Souza, Ana Carolina, Grabe‐Guimarães, Andrea, Cruz, Jader dos Santos, Santos‐Miranda, Artur, Farah, Charlotte, Teixeira Oliveira, Liliam, Lucas, Alexandre, Aimond, Franck, Sicard, Pierre, Mosqueira, Vanessa Carla Furtado, Richard, Sylvain

“…Background and Purpose The artemisinin derivative, artemether, has antimalarial activity with potential neurotoxic and cardiotoxic effects. Artemether in…”
Get full text

Pharmacological basis for use of Lychnophora trichocarpha in gouty arthritis: Anti-hyperuricemic and anti-inflammatory effects of its extract, fraction and constituents by de Souza, Maíra Ribeiro, de Paula, Carmen Aparecida, Pereira de Resende, Michelle Luciane, Grabe-Guimarães, Andrea, de Souza Filho, José Dias, Saúde-Guimarães, Dênia Antunes

“…The ethanolic extract of Lychnophora trichocarpha Spreng. is used in Brazilian folk medicine to treat bruise, pain and inflammatory diseases. The present study…”
Get full text

Polyester Nanocapsules for Intravenous Delivery of Artemether: Formulation Development, Antimalarial Efficacy, and Cardioprotective Effects In Vivo by Vidal-Diniz, Alessandra Teixeira, Guimarães, Homero Nogueira, Garcia, Giani Martins, Braga, Érika Martins, Richard, Sylvain, Grabe-Guimarães, Andrea, Mosqueira, Vanessa Carla Furtado

“…Artemether (ATM) is an effective antimalarial drug that also has a short half-life in the blood. Furthermore, ATM is also cardiotoxic and is associated with…”
Get full text

Caspofungin Effects on Electrocardiogram of Mice: An Evaluation of Cardiac Safety by De Paula, Danielle Cristiane Correa, Leite, Elaine Amaral, Araujo, Carolina Morais, Branquinho, Renata Tupinambá, Guimarães, Homero Nogueira, Grabe-Guimarães, Andrea

“…Caspofungin is an echinocandin, exhibiting efficacy against most Candida species invasive infection. Its cardiotoxicity was reported in isolated rat heart and…”
Get full text

Anti-inflammatory and antinociceptive activities of Campomanesia adamantium by Ferreira, Leidiane C, Grabe-Guimarães, Andrea, de Paula, Carmen A, Michel, Marcela C.P, Guimarães, Raquel G, Rezende, Simone A, de Souza Filho, José D, Saúde-Guimarães, Dênia A

“…Campomanesia species are used in folk medicine as anti-inflammatory, anti-rheumatic, anti-diarrheal and hypocholesterolemic. The present study investigated the…”
Get full text

Effect of pyridostigmine on in vivo and in vitro respiratory muscle of mdx mice by Amancio, Gabriela de Cássia Sousa, Grabe-Guimarães, Andrea, Haikel, Dridi, Moreau, Johan, Barcellos, Neila Marcia Silva, Lacampagne, Alain, Matecki, Stefan, Cazorla, Olivier

“…Highlights • Free PYR was more toxic to mdx mice than C57BL10 mice. • Liposomal PYR did not show any side effect, confirming that the encapsulation in…”
Get full text

Swim training attenuates the adverse remodeling of LV structural and mechanical properties in the early compensated phase of hypertension by Locatelli, Jamille, Paiva, Nívia C.N., Carvalho, Sara H.R., Lavorato, Victor N., Gomes, Luis Henrique L.S., Castro, Quênia J.T., Grabe-Guimarães, Andrea, Carneiro, Cláudia M., Natali, Antônio J., Isoldi, Mauro C.

“…Investigate to what extent low-intensity swim training for six weeks counterbalances the adverse remodeling due to the advance of pathological hypertrophy in…”
Get full text

Profile of wound healing process induced by allantoin by Araújo, Lorena Ulhôa, Grabe-Guimarães, Andrea, Mosqueira, Vanessa Carla Furtado, Carneiro, Claudia Martins, Silva-Barcellos, Neila Márcia

“…To evaluate and characterize the wound healing process profile induced by allantoin incorporated in soft lotion oil/water emulsion using the planimetric and…”
Get full text

Physical Exercise Combined with Antihypertensive Drug Therapy on Left Ventricular Hypertrophy: Systematic Review and Meta-Analysis by de Castro, Quênia Janaína Tomaz, Tomaz, Flávia Sílvia Corrêa, Watai, Patrícia Yoshie, Grabe-Guimarães, Andrea

“…Introduction Physical exercise and antihypertensive drugs contribute to reduce or prevent hypertensive heart disease (HHD). The effect on blood pressure (BP)…”
Get full text

A glimpse on a Brazilian pharmacology bibliography of the early-twentieth century by Weilher Paulo dos Santos, Andrea Grabe Guimarães

“…The pharmacology books used in teaching have changed considerably since late-nineteenth century. A professor of School of Pharmacy of Ouro Preto, Jovelino…”
Get full text

Cardiotoxicity reduction induced by halofantrine entrapped in nanocapsule devices by Leite, Elaine Amaral, Grabe-Guimarães, Andrea, Guimarães, Homero Nogueira, Machado-Coelho, George Luiz Lins, Barratt, Gillian, Mosqueira, Vanessa C.F.

“…The main objective of the present study was to evaluate the reduction in halofantrine (Hf) toxicity, an antimalarial drug frequently associated with QT…”
Get full text

Coleção de modelos anatômicos do Museu da Pharmacia da Universidade Federal de Ouro Preto by Sousa, Luiz Eduardo, Borges, Ingrid da Silva, Pimenta, Raphael David, Cunha, Thiago Rodrigues Araújo, Farias, Juliana de Paula, Naves, Sarah Meirielle Ferri, Amorim, Kalila Assis, Guimarães, Andrea Grabe

“…Resumo A Escola de Farmácia de Ouro Preto, fundada em 1839, foi a primeira da América Latina desvinculada de uma escola de medicina. No final do século XIX,…”
Get full text

Reduced cardiovascular alterations of tartar emetic administered in long-circulating liposomes in rats by Maciel, Naira R., Reis, Priscila G., Kato, Kelly C., Vidal, Alessandra T., Guimarães, Homero N., Frézard, Frederic, Silva-Barcellos, Neila M., Grabe-Guimarães, Andrea

“…Trivalent antimonial drugs, including tartar emetic (TA), are known to induce important cardiotoxicity observed by electrocardiographic abnormalities. Liposome…”
Get full text

Development and characterization of multilamellar liposomes containing pyridostigmine by Souza, Ana Carolina Moreira, Grabe-Guimarães, Andrea, Souza, Jacqueline, Botacim, Wallace Entringer, Almeida, Tamara Marine, Frézard, Fréderic Jean Georges, Silva Barcellos, Neila Márcia

“…Abstract Pyridostigmine has cardioprotective activity in both free and liposomal forms. This study aimed to develop and characterize liposomal formulations of…”
Get full text

Prolonged cardioprotective effect of pyridostigmine encapsulated in liposomes by Vidal, Alessandra Teixeira, Guimarães, Homero Nogueira, de Paula, Danielle Cristiane Correa, Frezard, Frederic, Silva-Barcellos, Neila Márcia, Grabe-Guimarães, Andrea

“…The purpose of the present work was to investigate the ability of pyridostigmine encapsulated in long-circulating liposomes, to protect against ECG…”
Get full text