Search Results - "Guillou, Lionel"
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Validation of MSIntuit as an AI-based pre-screening tool for MSI detection from colorectal cancer histology slides
Published in Nature communications (06-11-2023)“…Mismatch Repair Deficiency (dMMR)/Microsatellite Instability (MSI) is a key biomarker in colorectal cancer (CRC). Universal screening of CRC patients for MSI…”
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Measuring Cell Viscoelastic Properties Using a Microfluidic Extensional Flow Device
Published in Biophysical journal (01-11-2016)“…The quantification of cellular mechanical properties is of tremendous interest in biology and medicine. Recent microfluidic technologies that infer cellular…”
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Development and validation of a cellular host response test as an early diagnostic for sepsis
Published in PloS one (15-04-2021)“…Sepsis must be diagnosed quickly to avoid morbidity and mortality. However, the clinical manifestations of sepsis are highly variable and emergency department…”
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Numerical investigation of the dynamics of a rigid spherical particle in a vortical cross-slot flow at moderate inertia
Published in Microsystems & nanoengineering (26-07-2023)“…The study of flow and particle dynamics in microfluidic cross-slot channels is of high relevance for lab-on-a-chip applications. In this work, we investigate…”
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Mechanical Criterion for the Rupture of a Cell Membrane under Compression
Published in Biophysical journal (20-12-2016)“…We investigate the mechanical conditions leading to the rupture of the plasma membrane of an endothelial cell subjected to a local, compressive force. Membrane…”
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T-lymphocyte passive deformation is controlled by unfolding of membrane surface reservoirs
Published in Molecular biology of the cell (07-11-2016)“…T-lymphocytes in the human body routinely undergo large deformations, both passively, when going through narrow capillaries, and actively, when transmigrating…”
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Dynamic Monitoring of Cell Mechanical Properties using Profile Microindentation
Published in Biophysical journal (16-02-2016)Get full text
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Dynamic monitoring of cell mechanical properties using profile microindentation
Published in Scientific reports (09-02-2016)“…We have developed a simple and relatively inexpensive system to visualize adherent cells in profile while measuring their mechanical properties using…”
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T-lymphocyte passive deformation is controlled by unfolding of membrane surface reservoirs
Published in Molecular biology of the cell (07-11-2016)“…T-lymphocytes in the human body routinely undergo large deformations, both passively, when going through narrow capillaries, and actively, when transmigrating…”
Get full text
Journal Article