Search Results - "Guillot, Thomas S"

Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo by Lohr, Kelly M., Bernstein, Alison I., Stout, Kristen A., Dunn, Amy R., Lazo, Carlos R., Alter, Shawn P., Wang, Minzheng, Li, Yingjie, Fan, Xueliang, Hess, Ellen J., Yi, Hong, Vecchio, Laura M., Goldstein, David S., Guillot, Thomas S., Salahpour, Ali, Miller, Gary W.

“…Disruption of neurotransmitter vesicle dynamics (transport, capacity, release) has been implicated in a variety of neurodegenerative and neuropsychiatric…”
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Protective Actions of the Vesicular Monoamine Transporter 2 (VMAT2) in Monoaminergic Neurons by Guillot, Thomas S, Miller, Gary W

“…Vesicular monoamine transporters (VMATs) are responsible for the packaging of neurotransmitters such as dopamine, serotonin, norepinephrine, and epinephrine…”
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Reduced Vesicular Storage of Dopamine Causes Progressive Nigrostriatal Neurodegeneration by Caudle, W. Michael, Richardson, Jason R, Wang, Min Z, Taylor, Tonya N, Guillot, Thomas S, McCormack, Alison L, Colebrooke, Rebecca E, Di Monte, Donato A, Emson, Piers C, Miller, Gary W

“…The vesicular monoamine transporter 2 (VMAT2; SLC18A2) is responsible for packaging dopamine into vesicles for subsequent release and has been suggested to…”
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Developmental pesticide exposure reproduces features of attention deficit hyperactivity disorder by Richardson, Jason R., Taylor, Michele M., Shalat, Stuart L., Guillot, Thomas S., Caudle, W. Michael, Hossain, Muhammad M., Mathews, Tiffany A., Jones, Sara R., Cory‐Slechta, Deborah A., Miller, Gary W.

“…ABSTRACT Attention‐deficit hyperactivity disorder (ADHD) is estimated to affect 8‐12% of school‐age children worldwide. ADHD is a complex disorder with…”
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Increased Vesicular Monoamine Transporter 2 (VMAT2; Slc18a2) Protects against Methamphetamine Toxicity by Lohr, Kelly M, Stout, Kristen A, Dunn, Amy R, Wang, Minzheng, Salahpour, Ali, Guillot, Thomas S, Miller, Gary W

“…The psychostimulant methamphetamine (METH) is highly addictive and neurotoxic to dopamine terminals. METH toxicity has been suggested to be due to the release…”
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Selective Enhancement of Dopamine Release in the Ventral Pallidum of Methamphetamine-Sensitized Mice by Stout, Kristen A, Dunn, Amy R, Lohr, Kelly M, Alter, Shawn P, Cliburn, Rachel A, Guillot, Thomas S, Miller, Gary W

“…Drugs of abuse induce sensitization, which is defined as enhanced response to additional drug following a period of withdrawal. Sensitization occurs in both…”
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Reduced vesicular storage of dopamine exacerbates methamphetamine-induced neurodegeneration and astrogliosis by Guillot, Thomas S, Shepherd, Kennie R, Richardson, Jason R, Wang, Min Z, Li, Yingjie, Emson, Piers C, Miller, Gary W

“…The vesicular monoamine transporter 2 (VMAT2) controls the loading of dopamine (DA) into vesicles and therefore determines synaptic properties such as quantal…”
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Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo by Kelly M. Lohr, Alison I. Bernstein, Kristen A. Stout, Amy R. Dunn, Carlos R. Lazo, Shawn P. Alter, Minzheng Wang, Yingjie Li, Xueliang Fan, Ellen J. Hess, Hong Yi, Laura M. Vecchio, David S. Goldstein, Thomas S. Guillot, Ali Salahpour, Gary W. Miller

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PAP and NT5E Inhibit Nociceptive Neurotransmission by Rapidly Hydrolyzing Nucleotides to Adenosine by Street, Sarah E, Walsh, Paul L, Sowa, Nathaniel A, Taylor-Blake, Bonnie, Guillot, Thomas S, Vihko, Pirkko, Wightman, R Mark, Zylka, Mark J

“…Background: Prostatic acid phosphatase (PAP) and ecto-5'-nucleotidase (NT5E, CD73) produce extracellular adenosine from the nucleotide AMP in spinal…”
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Polychlorinated Biphenyl–Induced Reduction of Dopamine Transporter Expression as a Precursor to Parkinson's Disease–Associated Dopamine Toxicity by Caudle, W. Michael, Richardson, Jason R., Delea, Kristin C., Guillot, Thomas S., Wang, Minzheng, Pennell, Kurt D., Miller, Gary W.

“…Epidemiological and laboratory studies have suggested that exposure to polychlorinated biphenyls (PCBs) may be a risk factor for Parkinson's disease. The…”
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Pyrethroid pesticide-induced alterations in dopamine transporter function by Elwan, Mohamed A., Richardson, Jason R., Guillot, Thomas S., Caudle, W. Michael, Miller, Gary W.

“…Parkinson's disease (PD) is a progressive neurodegenerative disease affecting the nigrostriatal dopaminergic pathway. Several epidemiological studies have…”
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Industrial toxicants and Parkinson's disease by Caudle, W. Michael, Guillot, Thomas S., Lazo, Carlos R., Miller, Gary W.

“…The exposure of the human population to environmental contaminants is recognized as a significant contributing factor for the development of Parkinson's…”
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Efficacy of Low-Level Laser Therapy for Body Contouring and Spot Fat Reduction by Caruso-Davis, Mary K., Guillot, Thomas S., Podichetty, Vinod K., Mashtalir, Nazar, Dhurandhar, Nikhil V., Dubuisson, Olga, Yu, Ying, Greenway, Frank L.

“…Background Low-level laser therapy (LLLT) is commonly used in medical applications, but scientific studies of its efficacy and the mechanism by which it causes…”
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Synapsins differentially control dopamine and serotonin release by Kile, Brian M, Guillot, Thomas S, Venton, B Jill, Wetsel, William C, Augustine, George J, Wightman, R Mark

“…Synapsins are a family of synaptic vesicle proteins that are important for neurotransmitter release. Here we have used triple knock-out (TKO) mice lacking all…”
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Developmental pesticide exposure reproduces features of attention deficit hyperactivity disorder by Richardson, Jason R., Taylor, Michele M., Shalat, Stuart L., Guillot, Thomas S., Caudle, W. Michael, Hossain, Muhammad M., Mathews, Tiffany A., Jones, Sara R., Cory‐Slechta, Deborah A., Miller, Gary W.

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Reduced vesicular monoamine transport disrupts serotonin signaling but does not cause serotonergic degeneration by Alter, Shawn P., Stout, Kristen A., Lohr, Kelly M., Taylor, Tonya N., Shepherd, Kennie R., Wang, Minzheng, Guillot, Thomas S., Miller, Gary W.

“…We previously demonstrated that mice with reduced expression of the vesicular monoamine transporter 2 (VMAT2 LO) undergo age-related degeneration of the…”
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Dieldrin exposure induces oxidative damage in the mouse nigrostriatal dopamine system by Hatcher, Jaime M., Richardson, Jason R., Guillot, Thomas S., McCormack, Alison L., Di Monte, Donato A., Jones, Dean P., Pennell, Kurt D., Miller, Gary W.

“…Numerous epidemiological studies have shown an association between pesticide exposure and an increased risk of developing Parkinson's disease (PD). Here, we…”
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Obligatory Role for Complex I Inhibition in the Dopaminergic Neurotoxicity of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by Richardson, Jason R., Caudle, W. Michael, Guillot, Thomas S., Watson, Jodi L., Nakamaru-Ogiso, Eiko, Seo, Byoung Boo, Sherer, Todd B., Greenamyre, J. Timothy, Yagi, Takao, Matsuno-Yagi, Akemi, Miller, Gary W.

“…Administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to mice and nonhuman primates causes a parkinsonian disorder characterized by a loss of…”
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Chronically Implanted, Nafion-Coated Ag/AgCl Reference Electrodes for Neurochemical Applications by Hashemi, Parastoo, Walsh, Paul L, Guillot, Thomas S, Gras-Najjar, Julie, Takmakov, Pavel, Crews, Fulton T, Wightman, R. Mark

“…Fast-scan cyclic voltammetry at carbon-fiber microelectrodes can be used to measure behaviorally correlated dopamine changes in the extracellular fluid of the…”
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Optimizing the Temporal Resolution of Fast-Scan Cyclic Voltammetry by Kile, Brian M, Walsh, Paul L, McElligott, Zoé A, Bucher, Elizabeth S, Guillot, Thomas S, Salahpour, Ali, Caron, Marc G, Wightman, R. Mark

“…Electrochemical detection with carbon-fiber microelectrodes has become an established method to monitor directly the release of dopamine from neurons and its…”
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