Search Results - "Guillon, Michel"

The Effects of Age, Refractive Status, and Luminance on Pupil Size by Guillon, Michel, Dumbleton, Kathryn, Theodoratos, Panagiotis, Gobbe, Marine, Wooley, C Benjamin, Moody, Kurt

“…PURPOSEPupil size is critical for optimal performance of presbyopic contact lenses. Although the effect of luminance is well known, little information is…”
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Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study by Millard, Daniel, Dang, Qianyu, Shi, Hong, Zhang, Xiaou, Strock, Chris, Kraushaar, Udo, Zeng, Haoyu, Levesque, Paul, Lu, Hua-Rong, Guillon, Jean-Michel, Wu, Joseph C, Li, Yingxin, Luerman, Greg, Anson, Blake, Guo, Liang, Clements, Mike, Abassi, Yama A, Ross, James, Pierson, Jennifer, Gintant, Gary

“…Abstract Recent in vitro cardiac safety studies demonstrate the ability of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) to detect…”
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Tear film dynamics and lipid layer characteristics—Effect of age and gender by Maïssa, Cécile, Guillon, Michel

“…Abstract Purpose Dry eye disease is significantly more prevalent in older subjects and among them more marked in women than men. Further, it is established…”
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Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective by Vargas, Hugo M., Rolf, Michael G., Wisialowski, Todd A., Achanzar, William, Bahinski, Anthony, Bass, Alan, Benson, Charles T, Chaudhary, Khuram W., Couvreur, Nicolas, Dota, Corina, Engwall, Michael J, Michael Foley, C., Gallacher, David, Greiter‐Wilke, Andrea, Guillon, Jean‐Michel, Guth, Brian, Himmel, Herbert M., Hegele‐Hartung, Christa, Ito, Maki, Jenkinson, Stephen, Chiba, Katsuyoshi, Lagrutta, Armando, Levesque, Paul, Martel, Eric, Okai, Yoshiko, Peri, Ravikumar, Pointon, Amy, Qu, Yusheng, Teisman, Ard, Traebert, Martin, Yoshinaga, Takashi, Gintant, Gary A., Leishman, Derek J., Valentin, Jean‐Pierre

“…Defining an appropriate and efficient assessment of drug‐induced corrected QT interval (QTc) prolongation (a surrogate marker of torsades de pointes…”
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Contact Lens Wear Affects Tear Film Evaporation by Guillon, Michel, Maissa, Cécile

“…PURPOSE.The aim of the study was to measure tear film evaporation of both contact lens wearers (CLW) and nonwearers. The hypotheses tested were that (i)…”
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Association Between Contact Lens Discomfort and Pre-lens Tear Film Kinetics by Guillon, Michel, Dumbleton, Kathryn A, Theodoratos, Panagiotis, Wong, Stephanie, Patel, Kishan, Banks, Gaidig, Patel, Trisha

“…PURPOSEThe relationship between contact lens wettability and comfort has been extensively evaluated; however, a direct correlation between the characteristics…”
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Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation by Cavero, Icilio, Guillon, Jean-Michel, Ballet, Veronique, Clements, Mike, Gerbeau, Jean-Frédéric, Holzgrefe, Henry

“…The Comprehensive in vitro Proarrhythmia Assay (CiPA) is a nonclinical Safety Pharmacology paradigm for discovering electrophysiological mechanisms that are…”
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Recent advances on the estimation of the thermal reaction norm for sex ratios by Abreu-Grobois, F Alberto, Morales-Mérida, B Alejandra, Hart, Catherine E, Guillon, Jean-Michel, Godfrey, Matthew H, Navarro, Erik, Girondot, Marc

“…Temperature-dependent sex determination, or TSD, is a widespread phenomenon in reptiles. The shape of the relationship between constant incubation temperature…”
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The evaluation of drug-induced changes in cardiac inotropy in dogs: Results from a HESI-sponsored consortium by Guth, Brian D., Chiang, Alan Y., Doyle, Jennifer, Engwall, Michael J., Guillon, Jean-Michel, Hoffmann, Peter, Koerner, John, Mittelstadt, Scott, Ottinger, Sean, Pierson, Jennifer Beck, Pugsley, Michael K., Rossman, Eric I., Walisser, Jacqueline, Sarazan, R. Dustan

“…Drug-induced effects on the cardiovascular system remain a major cause of drug attrition. While hemodynamic (blood pressure (BP) and heart rate (HR)) and…”
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Efficacy and safety of dual-polymer hydroxypropyl guar- and hyaluronic acid-containing lubricant eyedrops for the management of dry-eye disease: a randomized double-masked clinical study by Labetoulle, Marc, Schmickler, Stefanie, Galarreta, David, Böhringer, Daniel, Ogundele, Abayomi, Guillon, Michel, Baudouin, Christophe

“…An artificial-tear formulation containing the dual polymers hydroxypropyl guar (HPG) and hyaluronic acid (HA) is approved for the treatment of dry-eye disease…”
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Effect of castor oil emulsion eyedrops on tear film composition and stability by Maïssa, Cécile, Guillon, Michel, Simmons, Peter, Vehige, Joseph

“…Abstract Purpose An emulsion eyedrop containing castor oil has been shown to modify the tear film lipid layer and increase tear film stability. The primary…”
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Are Silicone Hydrogel Contact Lenses More Comfortable Than Hydrogel Contact Lenses? by Guillon, Michel

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Molecular phylogeny of horsetails (Equisetum) including chloroplast atpB sequences by Guillon, J.M.(CNRS-Univ. Paris-Sud (France))

“…Equisetum is a genus of 15 extant species that are the sole surviving representatives of the class Sphenopsida. The generally accepted taxonomy of Equisetum…”
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Delimitation of the embryonic thermosensitive period for sex determination using an embryo growth model reveals a potential bias for sex ratio prediction in turtles by Girondot, Marc, Monsinjon, Jonathan, Guillon, Jean-Michel

“…The sexual phenotype of the gonad is dependent on incubation temperature in many turtles, all crocodilians, and some lepidosaurians. At hatching,…”
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Comment on: Carter AW, Paitz RT, Bowden RM. 2019. The Devil is in the Details: Identifying Aspects of Temperature Variation that Underlie Sex Determination in Species with TSD. Integrative and Comparative Biology 59:1081-8 by Monsinjon, Jonathan, Girondot, Marc, Guillon, Jean-Michel

“…We read with interest the article by Carter, Paitz, and Bowden entitled “The Devil is in the Details: Identifying Aspects of Temperature Variation that…”
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Female philopatry in a heterogeneous environment: ordinary conditions leading to extraordinary ESS sex ratios by Hulin, Vincent, Guillon, Jean-Michel

“…We use a simulation-based model to study the impact of female philopatry and heterogeneity of habitat quality on the evolution of primary sex ratio. We show…”
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Are Silicone Hydrogel Contact Lenses More Comfortable Than Hydrogel Contact Lenses? by Guillon, Michel

“…The current literature review was intended to investigate whether the use of silicone hydrogel contact lenses has resulted in improved comfort compared with…”
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Sex ratio evolution when fitness and dispersal vary by Guillon, Jean-Michel

“…In a heterogeneous environment, when the fitness of males and females are differently influenced by habitat quality, habitat-dependent sex ratios may evolve to…”
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Temperature-dependent sex determination and global change: are some species at greater risk? by Hulin, Vincent, Delmas, Virginie, Girondot, Marc, Godfrey, Matthew H, Guillon, Jean-Michel

“…In species with temperature-dependent sex determination (TSD), global climate change may result in a strong sex ratio bias that could lead to extinction. The…”
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Silicone hydrogel contact lenses effects on eyelid tissues: Lens care influence by Maissa, Cecile, PhD, Guillon, Michel, PhD FCOptom, Wong, Stephanie, BSc MCOptom, Lane, Anna, MOptom, Patel, Trisha, BSc, Garofalo, Renee, OD

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