Search Results - "Guillermo, Landi V. C."
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Immunomodulatory Effects of Green Tea Catechins and Their Ring Fission Metabolites in a Tumor Microenvironment Perspective
Published in Molecules (Basel, Switzerland) (26-09-2024)“…Green tea is the second most consumed beverage following water, and the health benefits provided by its consumption have been well established from research in…”
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The impact of pregnancy on the HIV-1-specific T cell function in infected pregnant women
Published in Clinical immunology (Orlando, Fla.) (01-12-2012)“…Abstract Evidences indicate that pregnancy can alter the Ag-specific T-cell responses. This work aims to evaluate the impact of pregnancy on the in vitro…”
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Caspase inhibition reduces lymphocyte apoptosis and improves host immune responses to Trypanosoma cruzi infection
Published in European Journal of Immunology (01-03-2007)“…In experimental Chagas’ disease, lymphocytes from mice infected with Trypanosoma cruzi show increased apoptosis in vivo and in vitro. Treatment with a…”
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Caspase-8 Activity Prevents Type 2 Cytokine Responses and Is Required for Protective T Cell-Mediated Immunity against Trypanosoma cruzi Infection
Published in The Journal of immunology (1950) (15-05-2005)“…During Trypanosoma cruzi infection, T cells up-regulate caspase-8 activity. To assess the role of caspase-8 in T cell-mediated immunity, we investigated the…”
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Inhibition of caspase-8 activity promotes protective Th1- and Th2-mediated immunity to Leishmania major infection
Published in Journal of leukocyte biology (01-02-2014)“…T cell expression of caspase‐8 inhibitor vFLIP provides a Th1 cytokine environment, along with a protective Th2 response that increases immunity to Leishmania…”
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Apoptosis differentially regulates mesenteric and subcutaneous lymph node immune responses to Trypanosoma cruzi
Published in European journal of immunology (2008)“…Infection with Trypanosoma cruzi causes expansion of subcutaneous (SLN) and atrophy of mesenteric (MLN) lymph nodes. Here we show that excision of MLN…”
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Decoding caspase signaling in host immunity to the protozoan Trypanosoma cruzi
Published in Trends in immunology (01-08-2007)“…Caspases, a family of cysteinyl–aspartate-specific proteases, induce apoptosis but are also involved in signal transduction in live cells. Caspase activation…”
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Cross-talk between apoptosis and cytokines in the regulation of parasitic infection
Published in Cytokine & growth factor reviews (01-02-2007)“…Abstract Parasitic diseases have worldwide medical and economical impact. Host T lymphocytes and the cytokines they produce determine the outcome of parasitic…”
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The impact of maternal anti-retroviral therapy on cytokine profile in the uninfected neonates
Published in Human immunology (01-09-2013)“…Abstract The number of HIV-infected young women has been increasing since the beginning of the AIDS epidemic. The objective of the present study was to…”
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Targeting caspases in intracellular protozoan infections
Published in Immunopharmacology and immunotoxicology (01-06-2009)“…Caspases are cysteine aspartases acting either as initiators (caspases 8, 9, and 10) or executioners (caspases 3, 6, and 7) to induce programmed cell death by…”
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Inhibition of caspase-8 activity reduces IFN-gamma expression by T cells from Leishmania major infection
Published in Anais da Academia Brasileira de Ciências (01-03-2008)“…Following infection with Leishmania major, T cell activation and apoptosis can be detected in draining lymph nodes of C57BL/6-infected mice. We investigated…”
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