Search Results - "Guillemin, Yannis"

c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1 by Campone, Mario, Noël, Bélinda, Couriaud, Cécile, Grau, Morgan, Guillemin, Yannis, Gautier, Fabien, Gouraud, Wilfried, Charbonnel, Catherine, Campion, Loïc, Jézéquel, Pascal, Braun, Frédérique, Barré, Benjamin, Coqueret, Olivier, Barillé-Nion, Sophie, Juin, Philippe

“…Anti-apoptotic signals induced downstream of HER2 are known to contribute to the resistance to current treatments of breast cancer cells that overexpress this…”
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Active fragments from pro- and antiapoptotic BCL-2 proteins have distinct membrane behavior reflecting their functional divergence by Guillemin, Yannis, Lopez, Jonathan, Gimenez, Diana, Fuertes, Gustavo, Valero, Juan Garcia, Blum, Loïc, Gonzalo, Philippe, Salgado, Jesùs, Girard-Egrot, Agnès, Aouacheria, Abdel

“…The BCL-2 family of proteins includes pro- and antiapoptotic members acting by controlling the permeabilization of mitochondria. Although the association of…”
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Use of GBT013, a Collagen-Based Dressing, for the Healing of Diabetic Foot Ulcers by Dumont, Isabelle J., Lepeut, Marc, Segalen, Coralie, Guillemin, Yannis, Gouze, Jean Noel

“…The number of people with diabetes is expected to reach 592 million in the year 2035. Diabetic foot lesions are responsible for more hospitalizations than any…”
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Bax-derived membrane-active peptides act as potent and direct inducers of apoptosis in cancer cells by Valero, Juan Garcia, Sancey, Lucie, Kucharczak, Jérôme, Guillemin, Yannis, Gimenez, Diana, Prudent, Julien, Gillet, Germain, Salgado, Jesús, Coll, Jean-Luc, Aouacheria, Abdel

“…Although many cancer cells are primed for apoptosis, they usually develop resistance to cell death at several levels. Permeabilization of the outer…”
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Escape from p21-mediated Oncogene-induced Senescence Leads to Cell Dedifferentiation and Dependence on Anti-apoptotic Bcl-xL and MCL1 Proteins by de Carné Trécesson, Sophie, Guillemin, Yannis, Bélanger, Audrey, Bernard, Anne-Charlotte, Preisser, Laurence, Ravon, Elisa, Gamelin, Erick, Juin, Philippe, Barré, Benjamin, Coqueret, Olivier

“…Oncogene-induced senescence (OIS) is a tumor suppressor response that induces permanent cell cycle arrest in response to oncogenic signaling. Through the…”
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Subcellular dynamics of the maternal cell death regulator BCL2L10 in human preimplantation embryos by Guérin, Jean-François, Cornut-Thibaut, Aurélie, Giscard-Destaing, Sandrine, Pouvreau, Sandrine, Guillemin, Yannis, Aouacheria, Abdel

“…STUDY QUESTION What is the expression status and subcellular localization of the maternally expressed Bcl-2 family member, BCL2L10, in early human embryos of…”
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Oocytes and early embryos selectively express the survival factor BCL2L10 by Guillemin, Yannis, Lalle, Philippe, Gillet, Germain, Guerin, Jean-François, Hamamah, Samir, Aouacheria, Abdel

“…Apoptosis has been reported in oocytes and human preimplantation embryos both in vitro and in vivo. BCL-2 family proteins are likely to play a pivotal role in…”
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Characterization of unique signature sequences in the divergent maternal protein Bcl2l10 by Guillemin, Yannis, Cornut-Thibaut, Aurélie, Gillet, Germain, Penin, François, Aouacheria, Abdel

“…Insertions or deletions (indels) of amino acids residues have been recognized as an important source of genetic and structural divergence between paralogous…”
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Characterization of Unique Signature Sequences in the Divergent Maternal Protein Bcl2l10 by Guillemin, Yannis, Cornut-Thibaut, Aurélie, Gillet, Germain, Penin, François, Aouacheria, Abdel

“…Insertions or deletions (indels) of amino acids residues have been recognized as an important source of genetic and structural divergence between paralogous…”
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Bax-derived membrane-active peptides act as potent and direct inducers of apoptosis in cancer cells: A membrane-active Bax peptide has antitumor activity by Valero, Juan Garcia, Sancey, Lucie, Kucharczak, Jérôme, Guillemin, Yannis, Gimenez, Diana, Prudent, Julien, Gillet, Germain, Salgado, Jesús, Coll, Jean-Luc, Aouacheria, Abdel

“…Although many cancer cells are primed for apoptosis, they usually develop resistance to cell death at several levels. Permeabilization of the outer…”
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74: Development of a novel membrane-active peptide with apoptosis-inducing activity and potent anticancer effect by Abdel, Aouacheria, Garcia Valero, Juan, Sancey, Lucie, Lopez, Jonathan, Guillemin, Yannis, Kucharczak, Jérôme, Salgado, Jesùs, Coll, Jean-Luc, Aouacheri, Abdel

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Modulating mitochondria-mediated apoptotic cell death through targeting of Bcl-2 family proteins by Aouacheria, Abdel, Cibiel, Agnès, Guillemin, Yannis, Gillet, Germain, Lalle, Philippe

“…Research demonstrated that the function of mitochondria extends well beyond that of being cell powerhouses and revealed that these organelles fulfil a dual…”
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