Search Results - "Guilherme M.J. Costa"

Progress and biotechnological prospects in fish transgenesis by Tonelli, Fernanda M.P., Lacerda, Samyra M.S.N., Tonelli, Flávia C.P., Costa, Guilherme M.J., de França, Luiz Renato, Resende, Rodrigo R.

“…The history of transgenesis is marked by milestones such as the development of cellular transdifferentiation, recombinant DNA, genetic modification of target…”
Get full text

Sub-acute intravenous administration of silver nanoparticles in male mice alters Leydig cell function and testosterone levels by Garcia, Thomas X., Costa, Guilherme M.J., França, Luiz R., Hofmann, Marie-Claude

“…•Silver nanoparticles were intravenously injected into male CD1 mice over 12 days.•Sperm concentration and motility, and mating and fertility indices were…”
Get full text

The Spermatogonial Stem Cell Niche in the Collared Peccary (Tayassu tajacu)1 by Campos-Junior, Paulo Henrique A, Costa, Guilherme M.J, Lacerda, Samyra M.S.N, Rezende-Neto, José V, de Paula, Ana M, Hofmann, Marie-Claude, de França, Luiz R

“…In the seminiferous epithelium, spermatogonial stem cells (SSCs) are located in a particular environment called the “niche” that is controlled by the basement…”
Get full text

Male reproductive toxicity of inorganic nanoparticles in rodent models: A systematic review by Dantas, Graziela P.F., Ferraz, Fausto S., Andrade, Lídia M., Costa, Guilherme M.J.

“…The use of nanoscale materials for different biomedical applications has grown a lot in the last years and raised several concerns about toxic effects on human…”
Get full text

Acute effects of atrazine on the immunoexpressions of sertoli and germ cells molecular markers, cytokines, chemokines, and sex hormones levels in mice testes and epididymides by Abarikwu, Sunny O., Coimbra, John L.P., Campolina-Silva, Gabriel, Rocha, Samuel Tadeu, Costa, Vivian Vasconcelos, Lacerda, Samyra M.S.N., Costa, Guilherme M.J.

“…Atrazine is currently one of the most commonly used agrochemicals in the United States and elsewhere. Here, we studied the immunoexpression of molecular…”
Get full text

Atrazine impairs testicular function in BalB/c mice by affecting Leydig cells by Abarikwu, Sunny O., Costa, Guilherme M.J., de Lima e Martins Lara, Nathalia, Lacerda, Samyra M.S.N., de França, Luiz R.

“…[Display omitted] •Atrazine exposure decreased Leydig cell’s 3β-HSD expression.•Caspase-3 expression in Leydig cells was increased by atrazine.•TUNEL staining…”
Get full text

Insights into Gold Nanoparticles Possibilities for Diagnosis and Treatment of the Head and Neck Upper Aerodigestive Tract Cancers by Andrade, Lídia M, Costa, Guilherme M J

“…Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer affecting people and accounts for more than 300,000 deaths worldwide…”
Get full text

Subchronic intake of arsenic at environmentally relevant concentrations causes histological lesions and oxidative stress in the prostate of adult Wistar rats by Coimbra, John L.P., Campolina-Silva, Gabriel, Lair, Daniel F., Guimarães-Ervilha, Luiz O., Souza, Ana C.F., Oliveira, Cleida A., Costa, Guilherme M.J., Machado-Neves, Mariana

“…The prostate gland is one of the main sites of hyperplasia and cancer in elderly men. Numerous factors have been demonstrated to disrupt prostate homeostasis,…”
Get full text

Testis structure, duration of spermatogenesis and daily sperm production in four wild cricetid rodent species (A. cursor, A. montensis, N. lasiurus, and O. nigripes) by Cordeiro, Jr, Dirceu A, Costa, Guilherme M J, França, Luiz R

“…Although rodents represent approximately 40% of all living mammalian species, our knowledge regarding their reproductive biology is still scarce. Due to their…”
Get full text

Effect of sphingosine-1-phosphate on cryopreserved sheep testicular explants cultured in vitro by Singh, Ram Pratap, Escobar, Enrique, Wildt, David, Patel, Seema, Costa, Guilherme M.J., Pukazhenthi, Budhan

“…Complete spermatogenesis has been achieved in vitro in mouse testicular explants with resulting sperm used to produce pups after Intra Cytoplasm Sperm…”
Get full text

MicroRNAs in Sertoli cells: implications for spermatogenesis and fertility by Procópio, Marcela S., de Avelar, Gleide F., Costa, Guilherme M. J., Lacerda, Samyra M. S. N., Resende, Rodrigo R., de França, Luiz R.

“…In recent decades, infertility has been considered a major widespread public health issue of very high concern. Currently, almost 50% of infertility cases are…”
Get full text

Gold nanoparticle intratesticular injections as a potential animal sterilization tool: Long-term reproductive and toxicological implications by Coimbra, John L.P., Dantas, Graziela de P.F., de Andrade, Lídia M., Brener, Marcos.R.G., Viana, Pedro I.M., Lopes, Roberta.A., O.G Gontijo, Daniele, Ervilha, Luiz.O.G., Assis, Mirian.Q., Barcelos, Luciola.S., E. Szawka, Raphael, Damasceno, Débora C., Machado-Neves, Mariana, Mota, Ana P., Costa, Guilherme M.J.

“…This study aimed to evaluate the gold nanoparticles (AuNPs) animal sterilizing potential after intratesticular injections and long-term adverse reproductive…”
Get full text

Effects of superparamagnetic iron oxide nanoparticles (SPIONS) testicular injection on Leydig cell function and sperm production in a murine model by Ferraz, Fausto S., Dantas, Graziela de P.F., Coimbra, John L.P., López, Jorge L., Lacerda, Samyra M.S.N., dos Santos, Mara L., Vieira, Carolina P., Lara, Nathália de L.E.M., Viana, Pedro I.M., Ladeira, Luiz O., Guarnieri, Leonardo O., Marçal, Eduardo M.A., Moraes, Márcio F.D., Martins, Estefânia M.N., Andrade, Lídia M., Costa, Guilherme M.J.

“…In the domain of medical advancement, nanotechnology plays a pivotal role, especially in the synthesis of biocompatible materials for therapeutic use…”
Get full text

Biotechnological approach to induce human fibroblast apoptosis using superparamagnetic iron oxide nanoparticles by Ferraz, Fausto S., López, Jorge L., Lacerda, Samyra M.S.N., Procópio, Marcela S., Figueiredo, André F.A., Martins, Estefânia M.N., Guimarães, Pedro P.G., Ladeira, Luiz O., Kitten, Gregory T., Dias, Felipe F., Domingues, Rosana Z., Costa, Guilherme M.J.

“…Cancer-Associated Fibroblasts (CAFs) contribute to tumour progression and have received significant attention as a therapeutic target. These cells produce…”
Get full text

Prepubertal PTU treatment in rat increases Sertoli cell number and sperm production by Figueiredo, André F A, Wnuk, Natália Teixeira, Tavares, Amanda O, Miranda, José Rafael, Hess, Rex A, de França, Luiz Renato, Costa, Guilherme M J

“…The number of Sertoli cells (SCs) ultimately determines the upper limit of sperm production in the testis. Previous studies have shown that thyroid hormones…”
Get full text

A new and fast technique to generate offspring after germ cells transplantation in adult fish: the Nile tilapia (Oreochromis niloticus) model by Lacerda, Samyra M S N, Batlouni, Sergio R, Costa, Guilherme M J, Segatelli, Tânia M, Quirino, Bruno R, Queiroz, Bruno M, Kalapothakis, Evanguedes, França, Luiz R

“…Germ cell transplantation results in fertile recipients and is the only available approach to functionally investigate the spermatogonial stem cell biology in…”
Get full text

Higher environmental temperatures promote acceleration of spermatogenesis in vivo in mice (Mus musculus) by Costa, Guilherme M.J., Lacerda, Samyra M.S.N., Figueiredo, André F.A., Leal, Marcelo C., Rezende-Neto, José V., França, Luiz R.

“…Temperature is considered a crucial modulator of reproductive activity and testis homeostasis. It is well known that elevated temperatures cause several…”
Get full text

Horse spermatogonial stem cell cryopreservation: feasible protocols and potential biotechnological applications by Costa, Guilherme M. J., Avelar, Gleide F., Lacerda, Samyra M. S. N., Figueiredo, André F. A., Tavares, Amanda O., Rezende-Neto, José V., Martins, Felipe G. P., França, Luiz R.

“…The establishment of proper conditions for spermatogonial stem cells (SSCs) cryopreservation and storage represents an important biotechnological approach for…”
Get full text

Morphofunctional evaluation of the testis, duration of spermatogenesis and spermatogenic efficiency in the Japanese fancy mouse (Mus musculus molossinus) by Costa, Guilherme M J, Leal, Marcelo C, França, Luiz R

“…Japanese fancy mouse, mini mouse or pet mouse are common names used to refer to strains of mice that present with different colour varieties and coat types…”
Get more information

Spermatogonial stem cell markers and niche in equids by Costa, Guilherme M J, Avelar, Gleide F, Rezende-Neto, José V, Campos-Junior, Paulo Henrique A, Lacerda, Samyra M S N, Andrade, Bruno S C, Thomé, Ralph Gruppi, Hofmann, Marie-Claude, Franca, Luiz R

“…Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis and are located in a highly dynamic microenvironment called "niche" that influences all…”
Get full text