Search Results - "Guilfoyle, Mathew R."

Recombinant Human Interleukin-1 Receptor Antagonist in Severe Traumatic Brain Injury: A Phase II Randomized Control Trial by Helmy, Adel, Guilfoyle, Mathew R, Carpenter, Keri LH, Pickard, John D, Menon, David K, Hutchinson, Peter J

“…Traumatic brain injury (TBI) is the commonest cause of death and disability in those aged under 40 years. Interleukin-1 receptor antagonist (IL1ra) is an…”
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Brain tissue oxygen monitoring in traumatic brain injury: part I—To what extent does PbtO2 reflect global cerebral physiology? by Svedung Wettervik, Teodor, Beqiri, Erta, Bögli, Stefan Yu, Placek, Michal, Guilfoyle, Mathew R, Helmy, Adel, Lavinio, Andrea, O'Leary, Ronan, Hutchinson, Peter J, Smielewski, Peter

“…Abstract Background The primary aim was to explore the association of global cerebral physiological variables including intracranial pressure (ICP),…”
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Characterising the dynamics of cerebral metabolic dysfunction following traumatic brain injury: A microdialysis study in 619 patients by Guilfoyle, Mathew R, Helmy, Adel, Donnelly, Joseph, Stovell, Matthew G, Timofeev, Ivan, Pickard, John D, Czosnyka, Marek, Smielewski, Peter, Menon, David K, Carpenter, Keri L H, Hutchinson, Peter J

“…Traumatic brain injury (TBI) is a major cause of death and disability, particularly amongst young people. Current intensive care management of TBI patients is…”
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Recombinant human interleukin-1 receptor antagonist promotes M1 microglia biased cytokines and chemokines following human traumatic brain injury by Helmy, Adel, Guilfoyle, Mathew R, Carpenter, Keri LH, Pickard, John D, Menon, David K, Hutchinson, Peter J

“…Interleukin-1 receptor antagonist (IL1ra) has demonstrated efficacy in a wide range of animal models of neuronal injury. We have previously published a…”
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Brain tissue oxygen monitoring in traumatic brain injury—part II: isolated and combined insults in relation to outcome by Svedung Wettervik, Teodor, Beqiri, Erta, Hånell, Anders, Bögli, Stefan Yu, Placek, Michal, Guilfoyle, Mathew R, Helmy, Adel, Lavinio, Andrea, O'Leary, Ronan, Hutchinson, Peter J, Smielewski, Peter

“…Abstract Background The primary aim was to explore the concept of isolated and combined threshold-insults for brain tissue oxygenation (pbtO 2 ) in relation to…”
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Cytokines and innate inflammation in the pathogenesis of human traumatic brain injury by Helmy, Adel, De Simoni, Maria-Grazia, Guilfoyle, Mathew R, Carpenter, Keri L H, Hutchinson, Peter J

“…There is an increasing recognition that following traumatic brain injury, a cascade of inflammatory mediators is produced, and contributes to the pathological…”
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Microdialysis-Based Classifications of Abnormal Metabolic States after Traumatic Brain Injury: A Systematic Review of the Literature by Venturini, Sara, Bhatti, Faheem, Timofeev, Ivan, Carpenter, Keri L H, Hutchinson, Peter J, Guilfoyle, Mathew R, Helmy, Adel

“…After traumatic brain injury (TBI), cerebral metabolism can become deranged, contributing to secondary injury. Cerebral microdialysis (CMD) allows cerebral…”
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Systemic inflammation alters the neuroinflammatory response: a prospective clinical trial in traumatic brain injury by Lassarén, Philipp, Lindblad, Caroline, Frostell, Arvid, Carpenter, Keri L H, Guilfoyle, Mathew R, Hutchinson, Peter J A, Helmy, Adel, Thelin, Eric Peter

“…Neuroinflammation following traumatic brain injury (TBI) has been shown to be associated with secondary injury development; however, how systemic inflammatory…”
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Reduced temporal muscle thickness predicts shorter survival in patients undergoing chronic subdural haematoma drainage by Korhonen, Tommi K., Arponen, Otso, Steinruecke, Moritz, Pecorella, Ilaria, Mee, Harry, Yordanov, Stefan, Viaroli, Edoardo, Guilfoyle, Mathew R., Kolias, Angelos, Timofeev, Ivan, Hutchinson, Peter, Helmy, Adel

“…Background Chronic subdural haematoma (CSDH) drainage is a common neurosurgical procedure. CSDHs cause excess mortality, which is exacerbated by frailty…”
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Principal component analysis of the cytokine and chemokine response to human traumatic brain injury by Helmy, Adel, Antoniades, Chrystalina A, Guilfoyle, Mathew R, Carpenter, Keri L H, Hutchinson, Peter J

“…There is a growing realisation that neuro-inflammation plays a fundamental role in the pathology of Traumatic Brain Injury (TBI). This has led to the search…”
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Epidural fentanyl for postoperative analgesia after lumbar canal decompression: a randomized controlled trial by Guilfoyle, Mathew R., BSc, MBBCh, MRCS, Mannion, Richard J., PhD, FRCS, Mitchell, Patrick, FRCS, Thomson, Simon, FRCS

“…Abstract Background context Postoperative back pain is common after decompression surgery for lumbar stenosis and often delays discharge from hospital…”
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Recovery of oculomotor nerve palsy secondary to posterior communicating artery aneurysms by Patel, Krunal, Guilfoyle, Mathew R., Bulters, Diederik O., Kirollos, Ramez W., Antoun, Nagui M., Higgins, J. Nicholas P., Kirkpatrick, Peter J., Trivedi, Rikin A.

“…Abstract Background. Recent studies suggest more favourable recovery of oculomotor nerve palsy (ONP) caused by posterior communicating artery (PComA) aneurysms…”
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Visualization of Cerebral Pressure Autoregulatory Insults in Traumatic Brain Injury by Svedung Wettervik, Teodor, Beqiri, Erta, Hånell, Anders, Yu Bögli, Stefan, Placek, Michal, Donnelly, Joseph, Guilfoyle, Mathew R, Helmy, Adel, Lavinio, Andrea, Hutchinson, Peter J, Smielewski, Peter

“…The first aim was to investigate the combined effect of insult intensity and duration of the pressure reactivity index (PRx) and deviation from the…”
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Glycemia Is Related to Impaired Cerebrovascular Autoregulation after Severe Pediatric Traumatic Brain Injury: A Retrospective Observational Study by Young, Adam M H, Adams, Hadie, Donnelly, Joseph, Guilfoyle, Mathew R, Fernandes, Helen, Garnett, Mathew R, Czosnyka, Marek, Smielewski, Peter, Plummer, Mark, Agrawal, Shruti, Hutchinson, Peter J

“…A strong association exists between hyperglycemia and outcome in pediatric traumatic brain injury (TBI). Herein, we describe observations of serum markers of…”
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Neurenteric cyst of the anterior cranial fossa: case report and literature review by Little, Mark W., Guilfoyle, Mathew R., Bulters, Diederik O., Scoffings, Daniel J., O’Donovan, Dominic G., Kirkpatrick, Peter J.

“…Intracranial neurenteric cysts are rare congenital lesions that typically occur in the posterior fossa. We report a case of a 70-year-old gentleman presenting…”
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Corrigendum: Glycemia Is Related to Impaired Cerebrovascular Autoregulation after Severe Pediatric Traumatic Brain Injury: A Retrospective Observational Study by Young, Adam M H, Adams, Hadie, Donnelly, Joseph, Guilfoyle, Mathew R, Fernandes, Helen, Garnett, Mathew R, Czosnyka, Marek, Smielewski, Peter, Plummer, Mark, Agrawal, Shruti, Hutchinson, Peter J

“…[This corrects the article on p. 205 in vol. 5, PMID: 28993802.]…”
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Regional Scalp Block for Postcraniotomy Analgesia: A Systematic Review and Meta-Analysis by Guilfoyle, Mathew R., Helmy, Adel, Duane, Derek, Hutchinson, Peter J. A.

“…Up to two-thirds of patients report moderate to severe surgical site pain after craniotomy procedures, and there is understandable reluctance to manage these…”
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Volumetric growth rates of meningioma and its correlation with histological diagnosis and clinical outcome: a systematic review by Fountain, Daniel M., Soon, Wai Cheong, Matys, Tomasz, Guilfoyle, Mathew R., Kirollos, Ramez, Santarius, Thomas

“…Introduction Tumour growth has been used to successfully predict progression-free survival in low-grade glioma. This systematic review sought to establish the…”
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Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma by Guilfoyle, Mathew R., Hutchinson, Peter J. A., Santarius, Thomas

“…Background Chronic subdural haematoma (CSDH) is a common condition that is effectively managed by burrhole drainage but requires repeat surgery in a…”
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Technical considerations and long-term results of endovascular venous stenting to control venous hypertension from meningiomas invading intracranial venous sinuses by Higgins, J Nicholas P, Kirollos, Sherif R W, Helmy, Adel, Guilfoyle, Mathew R, Pickard, John D, Axon, Patrick R, Joannides, Alexis J, Jefferies, Sarah, Santarius, Thomas, Kirollos, Ramez

“…Meningiomas invading the intracranial venous sinuses may cause intracranial venous hypertension, papilledema, and visual compromise. Sinus resection and graft…”
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