Search Results - "Guigó, R"
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Selenoprofiles: profile-based scanning of eukaryotic genome sequences for selenoprotein genes
Published in Bioinformatics (01-11-2010)“…Motivation: Selenoproteins are a group of proteins that contain selenocysteine (Sec), a rare amino acid inserted co-translationally into the protein chain. The…”
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SPIn: Model Selection for Phylogenetic Mixtures via Linear Invariants
Published in Molecular biology and evolution (01-03-2012)“…In phylogenetic inference, an evolutionary model describes the substitution processes along each edge of a phylogenetic tree. Misspecification of the model has…”
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Evaluation of Gene Structure Prediction Programs
Published in Genomics (San Diego, Calif.) (15-06-1996)“…We evaluate a number of computer programs designed to predict the structure of protein coding genes in genomic DNA sequences. Computational gene identification…”
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GeneID in Drosophila
Published in Genome research (01-04-2000)“…GeneID is a program to predict genes in anonymous genomic sequences designed with a hierarchical structure. In the first step, splice sites, and start and stop…”
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An assessment of gene prediction accuracy in large DNA sequences
Published in Genome research (01-10-2000)“…One of the first useful products from the human genome will be a set of predicted genes. Besides its intrinsic scientific interest, the accuracy and…”
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In silico identification of novel selenoproteins in the Drosophila melanogaster genome
Published in EMBO reports (01-08-2001)“…In selenoproteins, incorporation of the amino acid selenocysteine is specified by the UGA codon, usually a stop signal. The alternative decoding of UGA is…”
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SGP-1: prediction and validation of homologous genes based on sequence alignments
Published in Genome research (01-09-2001)“…Conventional methods of gene prediction rely on the recognition of DNA-sequence signals, the coding potential or the comparison of a genomic sequence with a…”
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Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs
Published in European heart journal (07-02-2015)“…Heart disease is recognized as a consequence of dysregulation of cardiac gene regulatory networks. Previously, unappreciated components of such networks are…”
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Exon structure conservation despite low sequence similarity: a relic of dramatic events in evolution?
Published in The EMBO journal (01-10-2001)“…The evolutionary significance of introns remains a mystery. The current availability of several complete eukaryotic genomes permits new studies to probe the…”
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Assembling genes from predicted exons in linear time with dynamic programming
Published in Journal of computational biology (1998)“…In a number of programs for gene structure prediction in higher eukaryotic genomic sequences, exon prediction is decoupled from gene assembly: a large pool of…”
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Reconstruction of Ancient Molecular Phylogeny
Published in Molecular phylogenetics and evolution (01-10-1996)“…Support for contradictory phylogenies is often obtained when molecular sequence data from different genes is used to reconstruct phylogenetic histories…”
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Prediction of gene structure
Published in Journal of molecular biology (05-07-1992)“…We have developed a hierarchical rule base system for identifying genes in DNA sequences. Atomic sites (such as initiation codons, stop codons, acceptor sites…”
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gff2ps: visualizing genomic annotations
Published in Bioinformatics (01-08-2000)“…gff2psis a program for visualizing annotations of genomic sequences. The program takes the annotated features on a genomic sequence in GFF format as input, and…”
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Fusion of the human gene for the polyubiquitination coeffector UEV1 with Kua, a newly identified gene
Published in Genome research (01-11-2000)“…UEV proteins are enzymatically inactive variants of the E2 ubiquitin-conjugating enzymes that regulate noncanonical elongation of ubiquitin chains. In…”
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Improving data and knowledge management to better integrate health care and research
Published in Journal of internal medicine (01-10-2013)Get full text
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Computational gene identification
Published in Journal of molecular medicine (Berlin, Germany) (01-06-1997)Get full text
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Genome sequence comparisons: hurdles in the fast lane to functional genomics
Published in Briefings in bioinformatics (01-11-2000)“…An important computational technique for extracting the wealth of information hidden in human genomic sequence data is to compare the sequence with that from…”
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Long noncoding RNAs as enhancers of gene expression
Published in Cold Spring Harbor Symposia on Quantitative Biology (2010)“…The human genome contains thousands of long noncoding RNAs (ncRNAs) transcribed from diverse genomic locations. A large set of long ncRNAs is transcribed…”
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Three-dimensional modelling of human cytochrome P450 1A2 and its interaction with caffeine and MeIQ
Published in Journal of computer-aided molecular design (01-07-1997)“…The three-dimensional modelling of proteins is a useful tool to fill the gap between the number of sequenced proteins and the number of experimentally known 3D…”
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A common pattern between the TGF-beta family and glutaredoxin
Published in Biochemical journal (15-12-1991)Get full text
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