Search Results - "Guido, Mario E"

Adjusting the Molecular Clock: The Importance of Circadian Rhythms in the Development of Glioblastomas and Its Intervention as a Therapeutic Strategy by Wagner, Paula M., Prucca, César G., Caputto, Beatriz L., Guido, Mario E.

“…Gliomas are solid tumors of the central nervous system (CNS) that originated from different glial cells. The World Health Organization (WHO) classifies these…”
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Enhancing structural diversity through chemical engineering of Ambrosia tenuifolia extract for novel anti-glioblastoma compounds by Adessi, Tonino G., Wagner, Paula M., Bisogno, Fabricio R., Nicotra, Viviana E., Guido, Mario E., García, Manuela E.

“…Natural products are an unsurpassed source of leading structures in drug discovery. The biosynthetic machinery of the producing organism offers an important…”
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Expression of Non-visual Opsins Opn3 and Opn5 in the Developing Inner Retinal Cells of Birds. Light-Responses in Müller Glial Cells by Rios, Maximiliano N, Marchese, Natalia A, Guido, Mario E

“…The avian retina is composed of different types of photoreceptors responsible for image and non-image forming tasks: the visual photoreceptor cells (cones and…”
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Chemotherapeutic Effect of SR9009, a REV-ERB Agonist, on the Human Glioblastoma T98G Cells by Wagner, Paula M., Monjes, Natalia M., Guido, Mario E.

“…Glioblastoma multiforme is the most aggressive brain tumor, and human T98G cells constitute a useful glioblastoma multiforme model to evaluate the…”
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The Intrinsic Blue Light Responses of Avian Müller Glial Cells Imply Calcium Release from Internal Stores by Marchese, Natalia A., Ríos, Maximiliano N., Guido, Mario E.

“…The retina of vertebrates is responsible for capturing light through visual (cones and rods) and non-visual photoreceptors (intrinsically photosensitive…”
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Non-Visual Photopigments Effects of Constant Light-Emitting Diode Light Exposure on the Inner Retina of Wistar Rats by Benedetto, María M, Guido, Mario E, Contin, María A

“…The retina is part of the central nervous system specially adapted to capture light photons and transmit this information to the brain through photosensitive…”
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Expression of novel opsins and intrinsic light responses in the mammalian retinal ganglion cell line RGC-5. Presence of OPN5 in the rat retina by Nieto, Paula S, Valdez, Diego J, Acosta-Rodríguez, Victoria A, Guido, Mario E

“…The vertebrate retina is known to contain three classes of photoreceptor cells: cones and rods responsible for vision, and intrinsically photoresponsive…”
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Reflections on Several Landmark Advances in Circadian Biology by Chawla, Sangeeta, Oster, Henrik, Duffield, Giles E, Maronde, Erik, Guido, Mario E, Chabot, Christopher, Dkhissi-Benyahya, Ouria, Provencio, Ignacio, Goel, Namni, Youngstedt, Shawn D, Zi-Ching Mak, Natalie, Caba, Mario, Nikhat, Anjoom, Chakrabarti, Shaon, Wang, Lei, Davis, Seth J

“…Circadian Biology intersects with diverse scientific domains, intricately woven into the fabric of organismal physiology and behavior. The rhythmic…”
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Early onset and differential temporospatial expression of melanopsin isoforms in the developing chicken retina by Verra, Daniela M, Contín, Maria Ana, Hicks, David, Guido, Mario E

“…Retinal ganglion cells (RGCs) expressing the photopigment melanopsin (Opn4) display intrinsic photosensitivity. In this study, the presence of nonvisual…”
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Inner retinal circadian clocks and non-visual photoreceptors: novel players in the circadian system by Guido, Mario E, Garbarino-Pico, Eduardo, Contin, Maria Ana, Valdez, Diego J, Nieto, Paula S, Verra, Daniela M, Acosta-Rodriguez, Victoria A, de Zavalía, Nuria, Rosenstein, Ruth E

“…Daily and annual changes in ambient illumination serve as specific stimuli that associate light with time and regulate the physiology of the organism through…”
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Effects of different per translational kinetics on the dynamics of a core circadian clock model by Nieto, Paula S, Revelli, Jorge A, Garbarino-Pico, Eduardo, Condat, Carlos A, Guido, Mario E, Tamarit, Francisco A

“…Living beings display self-sustained daily rhythms in multiple biological processes, which persist in the absence of external cues since they are generated by…”
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invertebrate-like phototransduction cascade mediates light detection in the chicken retinal ganglion cells by Contin, Maria Ana, Verra, Daniela M, Guido, Mario E

“…Prebilaterian animals perceived ambient light through nonvisual rhabdomeric photoreceptors (RPs), which evolved as support of the chordate visual system. In…”
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Disruption of the molecular clock severely affects lipid metabolism in a hepatocellular carcinoma cell model by Monjes, Natalia M., Wagner, Paula M., Guido, Mario E.

“…Involved in triglyceride (TG) and glycerophospholipid metabolism, the liver plays a crucial physiological role in the human body both as a major metabolic…”
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Circadian Regulation and Clock-Controlled Mechanisms of Glycerophospholipid Metabolism from Neuronal Cells and Tissues to Fibroblasts by Guido, Mario E., Monjes, Natalia M., Wagner, Paula M., Salvador, Gabriela A.

“…Along evolution, living organisms developed a precise timekeeping system, circadian clocks, to adapt life to the 24-h light/dark cycle and temporally regulate…”
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Arylalkylamine N‐acetyltransferase (AANAT): Blue light induction, nuclear translocation, and potential role in the survival of chicken retina neuronal cells by Rios, Maximiliano N., Marchese, Natalia A., Guido, Mario E.

“…In vertebrates, arylalkylamine N‐acetyltransferase (AANAT; EC 2.3.1.87) is the time‐keeping and key regulatory enzyme in melatonin (Mel) biosynthesis. AANAT is…”
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Temporal regulation of tumor growth in nocturnal mammals: In vivo studies and chemotherapeutical potential by Wagner, Paula M., Prucca, César G., Velazquez, Fabiola N., Sosa Alderete, Lucas G., Caputto, Beatriz L., Guido, Mario E.

“…Tumors of the nervous system including glioblastoma multiforme (GBM) are the most frequent and aggressive form of brain tumors; however, little is known about…”
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Pharmacological Modulation of the Cytosolic Oscillator Affects Glioblastoma Cell Biology by Wagner, Paula M., Fornasier, Santiago J., Guido, Mario E.

“…The circadian system is a conserved time-keeping machinery that regulates a wide range of processes such as sleep/wake, feeding/fasting, and activity/rest…”
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Retinal Ganglion Cells Are Autonomous Circadian Oscillators Synthesizing N-Acetylserotonin during the Day by Garbarino-Pico, Eduardo, Carpentieri, Agata R., Contin, Maria A., Sarmiento, María I. Keller, Brocco, Marcela A., Panzetta, Pedro, Rosenstein, Ruth E., Caputto, Beatriz L., Guido, Mario E.

“…Retinal ganglion cells send visual and circadian information to the brain regarding the environmental light-dark cycles. We investigated the capability of…”
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Rhythms in lipid droplet content driven by a metabolic oscillator are conserved throughout evolution by Wagner, Paula M., Salgado, Mauricio A., Turani, Ornella, Fornasier, Santiago J., Salvador, Gabriela A., Smania, Andrea M., Bouzat, Cecilia, Guido, Mario E.

“…The biological clock in eukaryotes controls daily rhythms in physiology and behavior. It displays a complex organization that involves the molecular…”
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c-Fos activated phospholipid synthesis is required for neurite elongation in differentiating PC12 cells by Gil, Germán A, Bussolino, Daniela F, Portal, Maximiliano M, Alfonso Pecchio, Adolfo, Renner, Marianne L, Borioli, Graciela A, Guido, Mario E, Caputto, Beatriz L

“…We have previously shown that c-Fos activates phospholipid synthesis through a mechanism independent of its genomic AP-1 activity. Herein, using PC12 cells…”
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