Search Results - "Gui, Shuangying"
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Factors affecting the structure of lyotropic liquid crystals and the correlation between structure and drug diffusion
Published in RSC advances (01-01-2018)“…Lyotropic liquid crystals (LLCs) formed by the self-assembly of amphiphilic molecules in a solvent (usually water) have attracted increasingly greater…”
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Smart stimuli-responsive hydrogels for drug delivery in periodontitis treatment
Published in Biomedicine & pharmacotherapy (01-06-2023)“…Periodontitis is a chronic inflammatory disease initiated by pathogenic biofilms and host immunity that damages tooth-supporting tissues, including the…”
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A candidate gene identified in converting platycoside E to platycodin D from Platycodon grandiflorus by transcriptome and main metabolites analysis
Published in Scientific reports (07-05-2021)“…Platycodin D and platycoside E are two triterpenoid saponins in Platycodon grandiflorus , differing only by two glycosyl groups structurally. Studies have…”
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Effects of Nongxiangxing baijiu (Chinese liquor) on mild alcoholic liver injury revealed by non-target metabolomics using ultra-performance liquid chromatography quadrupole-time-of-flight mass spectrometry
Published in Journal of bioscience and bioengineering (01-07-2022)“…Nongxiangxing baijiu (Chinese liquor) is one of the most widely consumed beverages in China. This liquor has been shown to contain large quantities of various…”
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Transcriptome analysis identifies putative genes involved in triterpenoid biosynthesis in Platycodon grandiflorus
Published in Planta (01-08-2021)“…Main conclusion Comprehensive transcriptome analysis of different Platycodon grandiflorus tissues discovered genes related to triterpenoid saponin…”
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Ros-responsive and scavenging bifunctional hydrogel enables co-delivery of anti-inflammatory agent and osteogenetic nanoparticle for periodontitis treatment
Published in Materials & design (01-03-2024)“…[Display omitted] •We developed an ROS-responsive and scavenging bifunctional injectable CC-B-CAPE@CY-NPs hydrogel for periodontitis treatment.•The…”
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Improvement of loperamide-hydrochloride-induced intestinal motility disturbance by Platycodon grandiflorum polysaccharides through effects on gut microbes and colonic serotonin
Published in Frontiers in cellular and infection microbiology (13-03-2023)“…Constipation is a common gastrointestinal symptom characterized by intestinal motility disorder. The effects of polysaccharides (PGP) on intestinal motility…”
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Carrier-free poly(glycyrrhetinic acid)-facilitated celastrol-loaded nanoparticle for high-efficiency low-toxicity treatment of rheumatoid arthritis
Published in Materials & design (01-05-2024)“…[Display omitted] •Drug-backboned polyglycyrrhetinic acid (PGA) was successfully synthesized by the condensation of glycyrrhetinic acid.•Carrier-free PGA@Cel…”
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Polyvinylpyrrolidone microneedles for localized delivery of sinomenine hydrochloride: preparation, release behavior of in vitro & in vivo, and penetration mechanism
Published in Drug delivery (01-01-2020)“…Sinomenine (SIN) is an anti-inflammatory alkaloid derived from Sinomenium acutum, and the products sinomenine hydrochloride (SH) tablets and injections have…”
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Development and Evaluation of Minocycline Hydrochloride-Loaded In Situ Cubic Liquid Crystal for Intra-Periodontal Pocket Administration
Published in Molecules (Basel, Switzerland) (06-09-2018)“…In the present study, an injectable in situ liquid crystal formulation was developed for local delivery of minocycline hydrochloride (MH) for chronic…”
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New insights into nanotherapeutics for periodontitis: a triple concerto of antimicrobial activity, immunomodulation and periodontium regeneration
Published in Journal of nanobiotechnology (04-01-2024)“…Periodontitis is a chronic inflammatory disease caused by the local microbiome and the host immune response, resulting in periodontal structure damage and even…”
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Platycodon grandiflorus decoction attenuates lipopolysaccharide-induced acute lung injury via the PI3K/Akt/NF-κB pathway
Published in Journal of functional foods (01-10-2024)“…[Display omitted] •PGD contains bioactive compounds, including glabridin, chrysin, 3,3′-dimethyl quercetin, ect.•PGD prevent LPS-induced ALI in in vitro.•PGD…”
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Simultaneously boosting inflammation resolution and osteogenic differentiation in periodontitis using folic acid-modified liposome-thermosensitive hydrogel composites
Published in Materials & design (01-10-2023)“…[Display omitted] •A folic acid-modified liposome-thermosensitive hydrogel composites (FA-GEN-Lip@Gel) was developed for in situ periodontal…”
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RNA interference-based nanosystems for inflammatory bowel disease therapy
Published in International Journal of Nanomedicine (01-01-2016)“…Inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, is a chronic, recrudescent disease that invades the gastrointestinal…”
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In situ hexagonal liquid crystal for intra-articular delivery of sinomenine hydrochloride
Published in Biomedicine & pharmacotherapy (01-09-2019)“…[Display omitted] •The ISH was prepared by a liquid precursor mixture containing phytantriol (PT), Vitamin E acetate (VEA), ethanol (ET), and water…”
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Quantitative and Chemical Fingerprint Analysis for the Quality Evaluation of Platycodi Radix Collected from Various Regions in China by HPLC Coupled with Chemometrics
Published in Molecules (Basel, Switzerland) (23-07-2018)“…Platycodi Radix (PR) is the root of (Jacq.) A. DC., which has been used for a long time in China to treat pulmonary diseases. The present study aimed to…”
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Transcriptome-wide identification of WRKY transcription factors and their expression profiles in response to methyl jasmonate in Platycodon grandiflorus
Published in Plant signaling & behavior (31-12-2022)“…Platycodon grandiflorus, a perennial flowering plant widely distributed in China and South Korea, is an excellent resource for both food and medicine. The main…”
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Genome-wide analysis of UDP-glycosyltransferases family and identification of UGT genes involved in drought stress of Platycodon grandiflorus
Published in Frontiers in plant science (29-04-2024)“…The uridine diphosphate (UDP)-glycosyltransferase (UGT) family is the largest glycosyltransferase family, which is involved in the biosynthesis of natural…”
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Uterine Metabolomics Reveals Protection of Taohong Siwu Decoction Against Abnormal Uterine Bleeding
Published in Frontiers in pharmacology (11-09-2020)“…Incomplete abortion, a procedure for terminating pregnancy, will lead to abnormal uterine bleeding (AUB), infections, and even death. Taohong Siwu decoction…”
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A Novel Phytantriol-Based In Situ Liquid Crystal Gel for Vaginal Delivery
Published in AAPS PharmSciTech (01-07-2019)“…The purpose of this paper was to evaluate the potential of in situ liquid crystal (LC) gels based on phytantriol (PYT) for vaginal delivery. The PYT-based in…”
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