Search Results - "Guggenhuber, Stephan"
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AAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitoxicity
Published in PloS one (21-12-2010)“…The CB1 cannabinoid receptor is the most abundant G-protein coupled receptor in the brain and a key regulator of neuronal excitability. There is strong…”
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Impaired anandamide/palmitoylethanolamide signaling in hippocampal glutamatergic neurons alters synaptic plasticity, learning, and emotional responses
Published in Neuropsychopharmacology (New York, N.Y.) (01-07-2019)“…Endocannabinoid signaling via anandamide (AEA) is implicated in a variety of neuronal functions and considered a promising therapeutic target for numerous…”
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Mitochondrial CB1 receptors regulate neuronal energy metabolism
Published in Nature neuroscience (04-03-2012)“…The authors show that the type-1 cannabinoid receptor (CB 1 ) is present in mouse neuronal mitochondrial membranes. They show that mitochondrial CB 1 receptors…”
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Impaired 2-AG Signaling in Hippocampal Glutamatergic Neurons: Aggravation of Anxiety-Like Behavior and Unaltered Seizure Susceptibility
Published in The international journal of neuropsychopharmacology (01-02-2016)“…Background: Postsynaptically generated 2-arachidonoylglycerol activates the presynaptic cannabinoid type-1 receptor, which is involved in synaptic plasticity…”
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Gadd45α modulates aversive learning through post‐transcriptional regulation of memory‐related mRNAs
Published in EMBO reports (01-06-2019)“…Learning is essential for survival and is controlled by complex molecular mechanisms including regulation of newly synthesized mRNAs that are required to…”
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Gadd45α modulates aversive learning through post‐transcriptional regulation of memory‐related mRNA s
Published in EMBO reports (01-06-2019)Get full text
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Cannabinoid receptor-interacting protein Crip1a modulates CB1 receptor signaling in mouse hippocampus
Published in Brain Structure and Function (01-05-2016)“…The cannabinoid type 1 receptor ( Cnr1 , CB1R) mediates a plethora of physiological functions in the central nervous system as a presynaptic modulator of…”
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Mitochondrial [CB.sub.1] receptors regulate neuronal energy metabolism
Published in Nature neuroscience (01-04-2012)“…The mammalian brain is one of the organs with the highest energy demands, and mitochondria are key determinants of its functions. Here we show that the type-1…”
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Mitochondrial CB sub(1) receptors regulate neuronal energy metabolism
Published in Nature neuroscience (01-03-2012)“…The mammalian brain is one of the organs with the highest energy demands, and mitochondria are key determinants of its functions. Here we show that the type-1…”
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