Search Results - "Guerret, M."

Routine determination of morphine, morphine 3-β-d-glucuronide and morphine 6-β-d-glucuronide in human serum by liquid chromatography coupled to electrospray mass spectrometry by Blanchet, M, Bru, G, Guerret, M, Bromet-Petit, M, Bromet, N

“…A robust liquid chromatographic mass spectrometric method capable of quantifying morphine, morphine 3-β-d-glucuronide and morphine 6-β-d-glucuronide down to…”
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Effect of Meal Timing Not Critical for the Pharmacokinetics of Tegaserod (HTF 919) by Zhou, Honghui, Khalilieh, Sauzanne, Lau, Henry, Guerret, Madeleine, Osborne, Stuart, Alladina, Latifa, Laurent, Aziz L., McLeod, James F.

“…This study assessed the pharmacokinetic profiles of administering tegaserod (HTF 919) at different time intervals with respect to a meal. It was a randomized,…”
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Single- and Multiple-Dose Pharmacokinetics of Sdz Htf 919 In Healthy Subjects by Appel‐Dingemanse, S., Guerret, M., Hirschberg, Y., McLeod, J.

“…Clinical Pharmacology & Therapeutics (1999) 65, 128–128; doi:…”
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Pharmacokinetics (PK) of SDZ HTF 919 (HTF) not altered in subjects with severe renal insufficiency requiring hemodialysis by Zhou, H., McLeod, J., Alladina, L., Guerret, M., Osborne, S., Lau, H., Lambrecht, L., Swan, S.K.

“…Clinical Pharmacology & Therapeutics (1999) 65, 203–203; doi:…”
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Cyclosporine and Nonsteroidal Antiinflammatory Drugs: Exploring Potential Drug Interactions and Their Implications for the Treatment of Rheumatoid Arthritis by Kovarik, J. M., Mueller, E. A., Gerbeau, C., Tarral, A., Francheteau, P., Guerret, M.

“…A series of clinical pharmacology studies was performed to screen for possible pharmacokinetic/dynamic contributions to drug interactions reported in…”
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Determination of pindolol in biological fluids by an electron-capture gas-liquid chromatographic method on a wall-coated open tubular column by Guerret, M

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Effect of nicardipine in elderly hypertensive patients by Forette, F., Bellet, M., Henry, JF, Hervy, MP, Poyard‐Salmeron, C., Bouchacourt, P., Guerret, M.

“…The purpose of this study was to test tolerance and the antihypertensive effect of nicardipine, a new calcium antagonist, in 31 elderly patients aged 57‐95…”
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Simultaneous study of the pharmacokinetics of intravenous and oral nicardipine using a stable isotope by GUERRET, M, CHEYMOL, G, HUBERT, M, JULIEN-LAROSE, C, LAVENE, D

“…The systemic elimination of nicardipine has been studied by an initial oral administration of nicardipine followed 1.25 h later by intravenous injection of the…”
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Role of isoflurane on hemodynamic properties and disposition of nicardipine by Chelly, J E, Hysing, E S, Abernethy, D R, Doursout, M F, Hartley, C J, Guerret, M, Merin, R G

“…Nicardipine properties (30 micrograms/kg i.v.) were studied in a group of eight dogs awake and anesthetized with isoflurane 1.6% end-tidal. Awake, nicardipine…”
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Parameters identification and optimal control in pharmacokinetics by Cherruault, Y., Guerret, M.

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Influence of digestive secretions and food on intestinal absorption of nicardipine by DELCHIER, J. C, GUERRET, M, VIDON, N, DUBRAY, C, LAVENE, D

“…The role of digestive absorption in the pharmacokinetics of nicardipine has been studied by the perfusion technique. Nicardipine (40 mg) was perfused in six…”
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Kinetics and hemodynamic effects of intravenous nicardipine modified by previous propranolol oral treatment by ROCHA, P, GUERRET, M, DAVID, D, MARCHAND, X, KAHN, J. C

“…Intravenous nicardipine, 5 mg, was administered in two comparable groups of eight patients with chronic coronary artery disease but no clinical signs of heart…”
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Determination of pindolol in biological fluids by electron-capture GLC by Guerret, M, Lavene, D, Kiechel, J R

“…An electron-capture GLC method was developed for measuring pindolol in human plasma and urine. The unchanged drug was extracted with benzene from alkalinized…”
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Longitudinal assessment of a P‐glycoprotein–mediated drug interaction of valspodar on digoxin by Kovarik, John M., Rigaudy, Laurence, Guerret, Madeleine, Gerbeau, Christophe, Rost, Karl‐Ludwig

“…Objectives Valspodar is a P‐glycoprotein modulator currently under development as a multidrug resistance reversal agent in clinical oncology. A multiple‐dose…”
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Determination of 3-hydroxy-guanfacine in biological fluids by electron-capture gas-liquid chromatography by Guerret, M, Julien-Larose, C, Kiechel, J R, Lavène, D

“…An electron-capture gas-liquid chromatographic method was developed for measuring 3-hydroxy-guanfacine, the main metabolite of guanfacine in human plasma and…”
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Determination of guanfacine in biological fluids by electron-capture GLC by Guerret, M, Lavene, D, Longchampt, J, Kiger, J L

“…A quantitative electron-capture GLC method with good sensitivity is described for the determination of guanfacine in human plasma and urine. By condensing its…”
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Estimation of the absolute oral bioavailability of pindolol by two analytical methods by GUERRET, M, CHEYMOL, G, AUBRY, J. P, CHEYMOL, A, LAVENE, D, KIECHEL, J. R

“…The absolute oral bioavailability of pindolol has been estimated by two analytical methods, fluorimetry and GLC-ECD. The study was carried out in six healthy…”
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Pharmacokinetic aspects of guanfacine withdrawal syndrome in a hypertensive patient with chronic renal failure by KIECHEL, J. R, LAVENE, D, GUERRET, M, COMOY, E, GODIN, M, FILLASTRE, J. P

“…The unusual observation of a withdrawal syndrome due to guanfacine in a hypertensive patient with chronic renal failure led to a study of the kinetics of the…”
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Quantification of ketotifen and its metabolites in human plasma by gas chromatography mass spectrometry by Julien-Larose, C, Guerret, M, Lavene, D, Kiechel, J R

“…Gas chromatography mass spectrometry with selected ion monitoring has been used to develop a method for the quantification of ketotifen and its demethylated,…”
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Evaluation of Effects of Terbinafine on Single Oral Dose Pharmacokinetics and Anticoagulant Actions of Warfarin in Healthy Volunteers by Guerret, Madeleine, Francheteau, Patrice, Hubert, Martine

“…Study Objective. To evaluate the potential effects of oral terbinafine, a new synthetic antifungal agent of the allylamine class, on the pharmacokinetics and…”
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