Search Results - "Guerrero Lopez, Jose Antonio"

The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation by Brohl, Andrew S, Solomon, David A, Chang, Wendy, Wang, Jianjun, Song, Young, Sindiri, Sivasish, Patidar, Rajesh, Hurd, Laura, Chen, Li, Shern, Jack F, Liao, Hongling, Wen, Xinyu, Gerard, Julia, Kim, Jung-Sik, Lopez Guerrero, Jose Antonio, Machado, Isidro, Wai, Daniel H, Picci, Piero, Triche, Timothy, Horvai, Andrew E, Miettinen, Markku, Wei, Jun S, Catchpool, Daniel, Llombart-Bosch, Antonio, Waldman, Todd, Khan, Javed

“…The Ewing sarcoma family of tumors (EFT) is a group of highly malignant small round blue cell tumors occurring in children and young adults. We report here the…”
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Immunohistochemical analysis and prognostic significance of PD-L1, PD-1, and CD8+ tumor-infiltrating lymphocytes in Ewing’s sarcoma family of tumors (ESFT) by Machado, Isidro, López-Guerrero, Jose Antonio, Scotlandi, Katia, Picci, Piero, Llombart-Bosch, Antonio

“…Ewing’s sarcoma family of tumors (ESFT) are aggressive neoplasms with scant tumor-infiltrating lymphocytes. We analyzed the immunohistochemical (IHC)…”
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Genome wide DNA methylation profiling identifies specific epigenetic features in high-risk cutaneous squamous cell carcinoma by Hervás-Marín, David, Higgins, Faatiemah, Sanmartín, Onofre, López-Guerrero, Jose Antonio, Bañó, M Carmen, Igual, J Carlos, Quilis, Inma, Sandoval, Juan

“…Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer. Although most cSCCs have good prognosis, a subgroup of high-risk cSCC has a…”
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A phase I dose-finding, pharmacokinetics and genotyping study of olaparib and lurbinectedin in patients with advanced solid tumors by Poveda, Andres, Oaknin, Ana, Romero, Ignacio, Guerrero-Zotano, Angel, Fariñas-Madrid, Lorena, Rodriguez-Freixinos, Victor, Mallol, Pedro, Lopez-Reig, Raquel, Lopez-Guerrero, Jose Antonio

“…The poly (ADP-Ribose) polymerase (PARP) inhibitor olaparib has shown antitumor activity in patients with ovarian or breast cancer with or without BRCA1/2…”
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Emerging treatment strategies in recurrent platinum-sensitive ovarian cancer: Focus on trabectedin by Poveda, Andrés, Ray-Coquard, Isabelle, Romero, Ignacio, Lopez-Guerrero, Jose Antonio, Colombo, Nicoletta

“…Abstract Ovarian cancer (OC) is the leading cause of death from gynecological malignancies. In spite of high response rates to the standard front-line…”
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GEIS 2013 guidelines for gastrointestinal sarcomas (GIST) by Poveda, Andrés, del Muro, Xavier García, López-Guerrero, Jose Antonio, Martínez, Virginia, Romero, Ignacio, Valverde, Claudia, Cubedo, Ricardo, Martín-Broto, Javier

“…Gastrointestinal stromal tumors (GIST) are the most common mesenchymal soft tissue sarcoma of the gastrointestinal tract. Correct diagnosis with thorough use…”
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A splice variant in the ACSL5 gene relates migraine with fatty acid activation in mitochondria by Matesanz, Fuencisla, Fedetz, María, Barrionuevo, Cristina, Karaky, Mohamad, Catalá-Rabasa, Antonio, Potenciano, Victor, Bello-Morales, Raquel, López-Guerrero, Jose-Antonio, Alcina, Antonio

“…Genome-wide association studies (GWAS) in migraine are providing the molecular basis of this heterogeneous disease, but the understanding of its aetiology is…”
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GEIS Guidelines for Gastrointestinal Sarcomas (GIST) by Poveda, Andrés, García del Muro, Xavier, Antonio López-Guerrero, Jose, Cubedo, Ricardo, Martínez, Virginia, Romero, Ignacio, Serrano, César, Valverde, Claudia, Martín-Broto, Javier

“…Abstract Gastrointestinal stromal sarcomas (GISTs) are the most common mesenchymal tumours originating in the digestive tract. They have a characteristic…”
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Immune dysregulation, autoimmunity, and granule defects in gray platelet syndrome by Collins, Janine H., Mayer, Louisa, Guerrero Lopez, Jose Antonio

“…Since the description of the first case with gray platelet syndrome (GPS) in 1971, this rare inherited platelet disorder has been the focus of extensive…”
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Prognostic relevance of CCN3 in Ewing sarcoma by Perbal, Bernard, PhD, Lazar, Noureddine, PhD, Zambelli, Diana, PhD, Lopez-Guerrero, Jose Antonio, PhD, Llombart-Bosch, Antonio, MD, Scotlandi, Katia, PhD, Picci, Piero, MD

“…Summary Ewing sarcoma is a highly aggressive malignant bone tumor occurring preferentially in children and young adults. At present, only clinical features,…”
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Dermatofibrosarcoma protuberans: clinical, pathological, and genetic (COL1A1-PDGFB ) study with therapeutic implications by Llombart, Beatriz, Sanmartín, Onofre, López-Guerrero, Jose Antonio, Monteagudo, Carlos, Serra, Carlos, Requena, Celia, Poveda, Andrés, Vistós, Juan Luis, Almenar, Sergio, Llombart-Bosch, Antonio, Guillén, Carlos

“…Aims:  To analyse the presence of collagen type I alpha 1–platelet‐derived growth factor beta (COL1A1–PDGFB) transcripts in 20 cases of dermatofibrosarcoma…”
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A unique set of 6 circulating microRNAs for early detection of non-small cell lung cancer by Halvorsen, Ann Rita, Bjaanæs, Maria, LeBlanc, Marissa, Holm, Are M, Bolstad, Nils, Rubio, Luis, Peñalver, Juan Carlos, Cervera, José, Mojarrieta, Julia Cruz, López-Guerrero, Jose Antonio, Brustugun, Odd Terje, Helland, Åslaug

“…Circulating microRNAs are promising biomarkers for diagnosis, predication and prognostication of diseases. Lung cancer is the cancer disease accountable for…”
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Histological heterogeneity of Ewing’s sarcoma/PNET: an immunohistochemical analysis of 415 genetically confirmed cases with clinical support by Llombart-Bosch, Antonio, Machado, Isidro, Navarro, Samuel, Bertoni, Franco, Bacchini, Patrizia, Alberghini, Marco, Karzeladze, Apollon, Savelov, Nikita, Petrov, Semyon, Alvarado-Cabrero, Isabel, Mihaila, Doina, Terrier, Philippe, Lopez-Guerrero, Jose Antonio, Picci, Piero

“…Ewing’s sarcoma (ES)/peripheral neuroectodermal tumor (PNET) are malignant neoplasms affecting children and young adults. We performed a study to typify the…”
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CDKN2A germline alterations in melanoma patients with personal or familial history of pancreatic cancer by De Unamuno, Blanca, García-Casado, Zaida, Bañuls, José, Requena, Celia, Lopez-Guerrero, José Antonio, Nagore, Eduardo

“…CDKN2A germline mutations increase the risk of melanoma development and are present in 20 and 10% of familial and multiple melanoma cases, respectively…”
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Expression of insulin-like growth factor system components in Ewing’s sarcoma and their association with survival by Scotlandi, Katia, Manara, Maria Cristina, Serra, Massimo, Marino, Maria Teresa, Ventura, Selena, Garofalo, Cecilia, Alberghini, Marco, Magagnoli, Giovanna, Ferrari, Stefano, Lopez-Guerrero, Jose Antonio, Llombard-Bosch, Antonio, Picci, Piero

“…Abstract Aims The role of IGF system in the pathogenesis of Ewing’s sarcoma (EWS) is well-documented. However, still little information is available about the…”
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Mutational Characterization of Cutaneous Melanoma Supports Divergent Pathways Model for Melanoma Development by Millán-Esteban, David, Peña-Chilet, María, García-Casado, Zaida, Manrique-Silva, Esperanza, Requena, Celia, Bañuls, José, López-Guerrero, Jose Antonio, Rodríguez-Hernández, Aranzazu, Traves, Víctor, Dopazo, Joaquín, Virós, Amaya, Kumar, Rajiv, Nagore, Eduardo

“…According to the divergent pathway model, cutaneous melanoma comprises a nevogenic group with a propensity to melanocyte proliferation and another one…”
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miRNAs as biomarkers in prostate cancer by Casanova-Salas, Irene, Rubio-Briones, José, Fernández-Serra, Antonio, López-Guerrero, Jose Antonio

“…Current prostate cancer (PCa) diagnosis is based in the serum prostate-specific antigen biomarker and digital rectal examination. However, these methods are…”
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Cytochrome P17 inhibition with ketoconazole as treatment for advanced granulosa cell ovarian tumor by Garcia-Donas, Jesus, Hurtado, Alicia, García-Casado, Zaida, Albareda, Judith, López-Guerrero, Jóse Antonio, Alemany, Isabel, Grande, Enrique, Camara, Juan Carlos, Hernando, Susana

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CUL4A , ERCC5 , and ERCC1 as Predictive Factors for Trabectedin Efficacy in Advanced Soft Tissue Sarcomas (STS): A Spanish Group for Sarcoma Research (GEIS) Study by Moura, David S, Sanchez-Bustos, Paloma, Fernandez-Serra, Antonio, Lopez-Alvarez, María, Mondaza-Hernandez, José L, Blanco-Alcaina, Elena, Gavilan-Naranjo, Angela, Martinez-Delgado, Paula, Lacerenza, Serena, Santos-Fernandez, Paloma, Carrasco-Garcia, Irene, Hidalgo-Rios, Samuel, Gutierrez, Antonio, Ramos, Rafael, Hindi, Nadia, Taron, Miguel, Lopez-Guerrero, Jose Antonio, Martin-Broto, Javier

“…A translational study was designed to analyze the expression of nucleotide excision repair (NER) and homologous recombination (HR) genes as potential…”
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Dermatofibrosarcoma protuberans: a comprehensive review and update on diagnosis and management by Llombart, Beatriz, MD, Serra-Guillén, Carlos, MD, Monteagudo, Carlos, MD, PhD, López Guerrero, José Antonio, PhD, Sanmartín, Onofre, MD

“…Dermatofibrosarcoma protuberans (DFSP) is a rare superficial tumor characterized by high rates of local recurrence and low risk of metastasis. DFSP occurs most…”
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