Search Results - "Guerrero, Lisa J."

Secreted protein acidic and rich in cysteine is a matrix scavenger chaperone by Chlenski, Alexandre, Guerrero, Lisa J, Salwen, Helen R, Yang, Qiwei, Tian, Yufeng, Morales La Madrid, Andres, Mirzoeva, Salida, Bouyer, Patrice G, Xu, David, Walker, Matthew, Cohn, Susan L

“…Secreted Protein Acidic and Rich in Cysteine (SPARC) is one of the major non-structural proteins of the extracellular matrix (ECM) in remodeling tissues. The…”
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Anti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors by Chlenski, Alexandre, Guerrero, Lisa J, Peddinti, Radhika, Spitz, Jared A, Leonhardt, Payton T, Yang, Qiwei, Tian, Yufeng, Salwen, Helen R, Cohn, Susan L

“…New, more effective strategies are needed to treat highly aggressive neuroblastoma. Our laboratory has previously shown that full-length Secreted Protein…”
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Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines by Yang, Qiwei, Tian, Yufeng, Ostler, Kelly R, Chlenski, Alexandre, Guerrero, Lisa J, Salwen, Helen R, Godley, Lucy A, Cohn, Susan L

“…Epigenetic aberrations and a CpG island methylator phenotype have been shown to be associated with poor outcomes in children with neuroblastoma (NB). Seven…”
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Secreted protein acidic and rich in cysteine (SPARC) induces lipotoxicity in neuroblastoma by regulating transport of albumin complexed with fatty acids by Chlenski, Alexandre, Dobratic, Marija, Salwen, Helen R, Applebaum, Mark, Guerrero, Lisa J, Miller, Ryan, DeWane, Gillian, Solomaha, Elena, Marks, Jeremy D, Cohn, Susan L

“…SPARC is a matrix protein that mediates interactions between cells and the microenvironment. In cancer, SPARC may either promote or inhibit tumor growth…”
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SPARC expression is associated with impaired tumor growth, inhibited angiogenesis and changes in the extracellular matrix by Chlenski, Alexandre, Liu, Shuqing, Guerrero, Lisa J., Yang, Qiwei, Tian, Yufeng, Salwen, Helen R., Zage, Peter, Cohn, Susan L.

“…Secreted protein, acidic and rich in cysteine (SPARC), is a multifunctional matricellular glycoprotein. In vitro, SPARC has antiangiogenic properties,…”
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Sorafenib inhibits neuroblastoma cell proliferation and signaling, blocks angiogenesis, and impairs tumor growth by Kakodkar, Nisha C., Peddinti, Radhika R., Tian, Yufeng, Guerrero, Lisa J., Chlenski, Alexandre, Yang, Qiwei, Salwen, Helen R., Maitland, Michael L., Cohn, Susan L.

“…Background More effective therapy for children with high‐risk neuroblastoma is desperately needed. Preclinical studies have shown that neuroblastoma tumor…”
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The quinoxaline anti-tumor agent (R+)XK469 inhibits neuroblastoma tumor growth by Kakodkar, Nisha C., Peddinti, Radhika, Kletzel, Morris, Tian, Yufeng, Guerrero, Lisa J., Undevia, Samir D., Geary, David, Chlenski, Alexandre, Yang, Qiwei, Salwen, Helen R., Cohn, Susan L.

“…The quinoxaline anti‐tumor agent (R+)XK469 mediates its effects by topoisomerase IIB inhibition. This report describes a 14‐year old with relapsed…”
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The Quinoxaline Antitumor Agent (R+)XK469 Inhibits Neuroblastoma Tumor Growth by Kakodkar, Nisha C., Peddinti, Radhika, Kletzel, Morris, Tian, Yufeng, Guerrero, Lisa J., Undevia, Samir D., Geary, David, Chlenski, Alexandre, Yang, Qiwei, Salwen, Helen R., Cohn, Susan L.

“…The quinoxaline antitumor agent (R+)XK469 mediates its effects by topoisomerase IIB inhibition. This report describes a 14 year-old with relapsed neuroblastoma…”
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