Search Results - "Guerra, Yasel"

Enzyme Inhibitors from Gorgonians and Soft Corals by Córdova-Isaza, Andrea, Jiménez-Mármol, Sofía, Guerra, Yasel, Salas-Sarduy, Emir

“…For decades, gorgonians and soft corals have been considered promising sources of bioactive compounds, attracting the interest of scientists from different…”
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Genetic diversity and natural selection of Plasmodium vivax reticulocyte invasion genes in Ecuador by Núñez, Andrés, Ntumngia, Francis B, Guerra, Yasel, Adams, John H, Sáenz, Fabián E

“…Knowledge of the diversity of invasion ligands in malaria parasites in endemic regions is essential to understand how natural selection influences genetic…”
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Identification of Tight-Binding Plasmepsin II and Falcipain 2 Inhibitors in Aqueous Extracts of Marine Invertebrates by the Combination of Enzymatic and Interaction-Based Assays by Salas-Sarduy, Emir, Guerra, Yasel, Covaleda Cortés, Giovanni, Avilés, Francesc Xavier, Chávez Planes, María A

“…Natural products from marine origin constitute a very promising and underexplored source of interesting compounds for modern biotechnological and…”
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Analysis of organizational power networks through a holistic approach using consensus strategies by Ramos, Valentina, Franco-Crespo, Antonio, González-Pérez, Lien, Guerra, Yasel, Ramos-Galarza, Carlos, Pazmiño, Pablo, Tejera, Eduardo

“…Power is one of the most complex organizational attributes to understand due to the multiple related variables and dimensions in which it appears. The…”
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Novel Devices for Transporting Protein Crystals to the Synchrotron Facilities and Thermal Protection of Protein Crystals by Flores-Ibarra, Andrea, Campos-Escamilla, Camila, Guerra, Yasel, Rudiño-Piñera, Enrique, Demitri, Nicola, Polentarutti, Maurizio, Cuéllar-Cruz, Mayra, Moreno, Abel

“…In this article, we use novel and non-conventional devices, based on polyolefins that help to increase the thermal protection of protein crystals in their…”
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Canonical or noncanonical? Structural plasticity of serine protease‐binding loops in Kunitz‐STI protease inhibitors by Guerra, Yasel, Armijos‐Jaramillo, Vinicio, Pons, Tirso, Tejera, Eduardo, Berry, Colin

“…The Kunitz‐Soybean Trypsin Inhibitor (Kunitz‐STI) family is a large family of proteins with most of its members being protease inhibitors. The versatility of…”
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The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach by Romero-Romero, Sergio, Costas, Miguel, Silva Manzano, Daniel-Adriano, Kordes, Sina, Rojas-Ortega, Erendira, Tapia, Cinthya, Guerra, Yasel, Shanmugaratnam, Sooruban, Rodríguez-Romero, Adela, Baker, David, Höcker, Birte, Fernández-Velasco, D. Alejandro

“…[Display omitted] •The TIM barrel is a versatile fold to understand structure-stability relationships.•A collection of de novo TIM barrels with improved…”
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Stable monomers in the ancestral sequence reconstruction of the last opisthokont common ancestor of dimeric triosephosphate isomerase by Pérez‐Niño, Jorge Alejandro, Guerra, Yasel, Díaz‐Salazar, A. Jessica, Costas, Miguel, Rodríguez‐Romero, Adela, Fernández‐Velasco, D. Alejandro

“…Function and structure are strongly coupled in obligated oligomers such as Triosephosphate isomerase (TIM). In animals and fungi, TIM monomers are inactive and…”
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Critical Review of Plant-Derived Compounds as Possible Inhibitors of SARS-CoV‑2 Proteases: A Comparison with Experimentally Validated Molecules by Guerra, Yasel, Celi, Diana, Cueva, Paul, Perez-Castillo, Yunierkis, Giampieri, Francesca, Alvarez-Suarez, José Miguel, Tejera, Eduardo

“…Ever since coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, was declared a pandemic on March 11, 2020, by the WHO, a concerted effort has been made…”
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Structures of a bi-functional Kunitz-type STI family inhibitor of serine and aspartic proteases: Could the aspartic protease inhibition have evolved from a canonical serine protease-binding loop? by Guerra, Yasel, Valiente, Pedro A., Pons, Tirso, Berry, Colin, Rudiño-Piñera, Enrique

“…Bi-functional inhibitors from the Kunitz-type soybean trypsin inhibitor (STI) family are glycosylated proteins able to inhibit serine and aspartic proteases…”
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Structures of a bi-functional Kunitz-type STI family inhibitor of serine and aspartic proteases: Could the aspartic protease inhibition have evolved from a canonical serine protease-binding loop? by Guerra, Yasel, Valiente, Pedro A., Pons, Tirso, Berry, Colin, Rudiño-Piñera, Enrique

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Predicting functional residues of the Solanum lycopersicum aspartic protease inhibitor (SLAPI) by combining sequence and structural analysis with molecular docking by Guerra, Yasel, Valiente, Pedro A., Berry, Colin, Pons, Tirso

“…The Solanum lycopersicum aspartic protease inhibitor (SLAPI), which belongs to the STI-Kunitz family, is an effective inhibitor of the aspartic proteases human…”
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Generation of an affinity matrix useful in the purification of natural inhibitors of plasmepsin II, an antimalarial-drug target by Ramírez, Angel R, Guerra, Yasel, Otero, Anabel, García, Beatriz, Berry, Colin, Mendiola, Judith, Hernández-Zanui, Aida, Chávez, María de Los A

“…An affinity matrix containing the antimalarial drug target Plm II (plasmepsin II) as ligand was generated. This enzyme belongs to the family of Plasmodium…”
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Generation of an affinity matrix useful in the purification of natural inhibitors of plasmepsin II, an antimalarial-drug target by Ramírez, Angel R., Guerra, Yasel, Otero, Anabel, García, Beatriz, Berry, Colin, Mendiola, Judith, Hernández-Zanui, Aida, Chávez, María de los A.

“…An affinity matrix containing the antimalarial drug target Plm II (plasmepsin II) as ligand was generated. This enzyme belongs to the family of Plasmodium…”
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Changes in metabolic and immunological variables of wild and pond-reared southern white shrimp Litopenaeus schmitti adult males during continuous reproductive activity by Pérez-Jar, Lourdes, Rodríguez-Ramos, Tania, Ramos, Laida, Guerra-Borrego, Yasel, Racotta, Ilie S.

“…Reproductive performance of male southern white shrimp Litopenaeus schmitti decreased over time possibly attaining a reproductive exhaustion that results in a…”
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