Search Results - "Guerra, Leah"
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miR-181a Promotes Multiple Protumorigenic Functions by Targeting TGFβR3
Published in Journal of investigative dermatology (01-07-2022)“…Cutaneous squamous cell carcinoma (cSCC) comprises 15‒20% of all skin cancers and has a well-defined progression sequence from precancerous actinic keratosis…”
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Fibroblast Growth Factor Receptor 1 Drives the Metastatic Progression of Prostate Cancer
Published in European urology oncology (01-04-2022)“…The prometastatic effects of fibroblast growth factor receptor 1 (FGFR1) in prostate cancer emphasize the need to develop FGFR blockade as therapy for prostate…”
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Bone-derived excess TGF-ß release is associated with cognitive dysfunction due to oxidation of RyR, Ca2+ leak and mitochondrial dysfunction
Published in Journal of bone oncology (01-04-2024)Get full text
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Radium-223 Treatment Increases Immune Checkpoint Expression in Extracellular Vesicles from the Metastatic Prostate Cancer Bone Microenvironment
Published in Clinical cancer research (01-06-2021)“…Radium-223 prolongs survival in a fraction of men with bone metastatic prostate cancer (PCa). However, there are no markers for monitoring response and…”
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miR-181a promotes multiple pro-tumorigenic functions through targeting TGFβR3
Published in Journal of investigative dermatology (08-12-2021)“…Cutaneous squamous cell carcinoma (cuSCC) comprises 15–20% of all skin cancers and has a well-defined progression sequence from precancerous actinic keratosis…”
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Abstract 2761: Activating RET mutations promotes osteoblastic bone metastasis by inhibiting osteoclastogenesis and stimulating osteoblast activity via regulation of osteoprotegerin
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Bone metastases (BM) are a source of increased mortality and significant morbidity in patients with medullary thyroid cancer (MTC), with ~50% survival…”
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Abstract 3208: Bone-derived TGF-ß release is associated with cardiac dysfunction due to oxidation of SR calcium gatekeepers, Ca2+ leak and mitochondrial dysfunction
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Cancer patients with bone metastases are associated with cardiac dysfunction. Heart attack was observed in 3.8% of patients within 30 days of…”
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Study of para-Quinone Methide Precursors toward the Realkylation of Aged Acetylcholinesterase
Published in ACS medicinal chemistry letters (08-06-2017)“…Acetylcholinesterase (AChE) is an essential enzyme that can be targeted by organophosphorus (OP) compounds, including nerve agents. Following exposure to OPs,…”
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