Search Results - "Guerini‐Rocco, Elena"

Mismatch repair-deficient hormone receptor-positive breast cancers: Biology and pathological characterization by Sajjadi, Elham, Venetis, Konstantinos, Piciotti, Roberto, Invernizzi, Marco, Guerini-Rocco, Elena, Haricharan, Svasti, Fusco, Nicola

“…The clinical outcome of patients with a diagnosis of hormone receptor (HR)+ breast cancer has improved remarkably since the arrival of endocrine therapy. Yet,…”
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Optimizing tissue stewardship in non‐small cell lung cancer to support molecular characterization and treatment selection: statement from a working group of thoracic pathologists by Kerr, Keith M, Bubendorf, Lukas, Lopez‐Rios, Fernando, Khalil, Farah, Roy‐Chowdhuri, Sinchita, Joubert, Philippe, Hartmann, Arndt, Guerini‐Rocco, Elena, Yatabe, Yasushi, Hofman, Paul, Cooper, Wendy A, Dacic, Sanja

“…Many patients with non‐small cell lung cancer do not receive guideline‐recommended, biomarker‐directed therapy, despite the potential for improved clinical…”
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The Evolving Role of Genomic Testing in Early Breast Cancer: Implications for Diagnosis, Prognosis, and Therapy by Venetis, Konstantinos, Pescia, Carlo, Cursano, Giulia, Frascarelli, Chiara, Mane, Eltjona, De Camilli, Elisa, Munzone, Elisabetta, Dellapasqua, Silvia, Criscitiello, Carmen, Curigliano, Giuseppe, Guerini Rocco, Elena, Fusco, Nicola

“…Multigene prognostic genomic assays have become indispensable in managing early breast cancer (EBC), offering crucial information for risk stratification and…”
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A role for the immune system in advanced laryngeal cancer by Tagliabue, Marta, Maffini, Fausto, Fumagalli, Caterina, Gandini, Sara, Lepanto, Daniela, Corso, Federica, Cacciola, Salvatore, Ranghiero, Alberto, Rappa, Alessandra, Vacirca, Davide, Cossu Rocca, Maria, Alterio, Daniela, Guerini Rocco, Elena, Cattaneo, Augusto, Chu, Francesco, Zorzi, Stefano, Curigliano, Giuseppe, Chiocca, Susanna, Barberis, Massimo, Viale, Giuseppe, Ansarin, Mohssen

“…To investigate the role of the altered activation of the immune system in the prognosis of patients affected by laryngeal squamous cell carcinoma (LSCC). We…”
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Tumor BRCA Testing in Epithelial Ovarian Cancers: Past and Future-Five-Years' Single-Institution Experience of 762 Consecutive Patients by Fumagalli, Caterina, Betella, Ilaria, Rappa, Alessandra, di Giminiani, Maria, Gaiano, Michela, De Vitis, Luigi Antonio, Zambetti, Benedetta, Vacirca, Davide, Multinu, Francesco, Venetis, Konstantinos, Colombo, Nicoletta, Barberis, Massimo, Guerini Rocco, Elena

“…The establishment of PARP inhibitors in the treatment of epithelial ovarian carcinoma (EOC) has prompt BRCA assessment at the time of diagnosis. We described…”
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Whole‐exome sequencing and RNA sequencing analyses of acinic cell carcinomas of the breast by Beca, Francisco, Lee, Simon S K, Pareja, Fresia, Da Cruz Paula, Arnaud, Selenica, Pier, Ferrando, Lorenzo, Gularte‐Mérida, Rodrigo, Wen, Hannah Y, Zhang, Hong, Guerini‐Rocco, Elena, Rakha, Emad A, Weigelt, Britta, Reis‐Filho, Jorge S

“…Aims Acinic cell carcinoma (ACC) of the breast is a rare histological form of triple‐negative breast cancer (TNBC). Despite its unique histology, targeted…”
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Digital Pathology and PD-L1 Testing in Non Small Cell Lung Cancer: A Workshop Record by Pagni, Fabio, Malapelle, Umberto, Doglioni, Claudio, Fontanini, Gabriella, Fraggetta, Filippo, Graziano, Paolo, Marchetti, Antonio, Guerini Rocco, Elena, Pisapia, Pasquale, Vigliar, Elena V., Buttitta, Fiamma, Jaconi, Marta, Fusco, Nicola, Barberis, Massimo, Troncone, Giancarlo

“…A meeting among expert pathologists was held in 2019 in Rome to verify the results of the previous harmonization efforts on the PD-L1 immunohistochemical…”
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The molecular landscape of breast mucoepidermoid carcinoma by Venetis, Konstantinos, Sajjadi, Elham, Ivanova, Mariia, Andaloro, Silvia, Pessina, Simona, Zanetti, Chiara, Ranghiero, Alberto, Citelli, Gabriele, Rossi, Chiara, Lucioni, Marco, Malapelle, Umberto, Pagni, Fabio, Barberis, Massimo, Guerini-Rocco, Elena, Viale, Giuseppe, Fusco, Nicola

“…Mucoepidermoid carcinoma (MEC) of the breast is an extremely rare salivary gland-type tumor characterized by epidermoid, basaloid, intermediate, and/or…”
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Revolutionizing Cancer Research: The Impact of Artificial Intelligence in Digital Biobanking by Frascarelli, Chiara, Bonizzi, Giuseppina, Musico, Camilla Rosella, Mane, Eltjona, Cassi, Cristina, Guerini Rocco, Elena, Farina, Annarosa, Scarpa, Aldo, Lawlor, Rita, Reggiani Bonetti, Luca, Caramaschi, Stefania, Eccher, Albino, Marletta, Stefano, Fusco, Nicola

“…Background. Biobanks are vital research infrastructures aiming to collect, process, store, and distribute biological specimens along with associated data in an…”
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Successful treatment with avapritinib in patient with mucosal metastatic melanoma by Cocorocchio, Emilia, Pala, Laura, Conforti, Fabio, Guerini-Rocco, Elena, De Pas, Tommaso, Ferrucci, Pier Francesco

“…Metastatic vulvar melanoma is a rare and aggressive disease and survival is usually poor. Vulvar melanomas harbor BRAF V600 mutations only infrequently;…”
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Reproducibility of mRNA-Based Testing of ESR1, PGR, ERBB2, and MKI67 Expression in Invasive Breast Cancer—A Europe-Wide External Quality Assessment by Erber, Ramona, Hartmann, Arndt, Fasching, Peter Andreas, Ruebner, Matthias, Stöhr, Robert, Beckmann, Matthias Wilhelm, Zentgraf, Miriam, Popp, Verena, Weidler, Jodi, Simon, Iris, Becker, Steffi, Huebner, Hanna, Fischer, Josephine, Guerini Rocco, Elena, Viale, Giuseppe, Cayre, Anne, Penault-Llorca, Frederique, Caniego Casas, Tamara, Pérez-Miés, Belén, Palacios, José, Jank, Paul, Denkert, Carsten, Khoury, Lina, Mairinger, Thomas, Ferrazzi, Fulvia

“…Estrogen receptor (ER), progesterone receptor (PgR), Ki-67, and HER2 immunohistochemistry (IHC) together with HER2 in situ hybridization (ISH) are utilized to…”
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Concordance between Three PD-L1 Immunohistochemical Assays in Head and Neck Squamous Cell Carcinoma (HNSCC) in a Multicenter Study by Guerini Rocco, Elena, Eccher, Albino, Girolami, Ilaria, Graziano, Paolo, Fontanini, Gabriella, Vigliar, Elena, Troncone, Giancarlo, Barberis, Massimo, Morbini, Patrizia, Martini, Maurizio

“…The introduction of immunotherapy targeting the programmed death-1 (PD-1)/programmed death-ligand-1 (PD-L1) axis has represented a turning point in the…”
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Author Correction: A role for the immune system in advanced laryngeal cancer by Tagliabue, Marta, Maffini, Fausto, Fumagalli, Caterina, Gandini, Sara, Lepanto, Daniela, Corso, Federica, Cacciola, Salvatore, Ranghiero, Alberto, Rappa, Alessandra, Vacirca, Davide, Cossu Rocca, Maria, Alterio, Daniela, Guerini Rocco, Elena, Cattaneo, Augusto, Chu, Francesco, Zorzi, Stefano, Curigliano, Giuseppe, Chiocca, Susanna, Barberis, Massimo, Viale, Giuseppe, Ansarin, Mohssen

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Emergency Lung Transplantation after COVID-19: Immunopathological Insights on Two Affected Patients by Croci, Giorgio A, Vaira, Valentina, Trabattoni, Daria, Biasin, Mara, Valenti, Luca, Baselli, Guido, Barberis, Massimo, Guerini Rocco, Elena, Gregato, Giuliana, Scandroglio, Mara, Fominskiy, Evgeny, Palleschi, Alessandro, Rosso, Lorenzo, Nosotti, Mario, Clerici, Mario, Ferrero, Stefano

“…We herein characterize the immunopathological features of two Italian COVID-19 patients who underwent bilateral lung transplantation (bLTx). Removed lungs…”
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Contrast-Enhanced Computed Tomography Colonography in Preoperative Distinction between T1-T2 and T3-T4 Staging of Colon Cancer by Flor, Nicola, MD, Mezzanzanica, Miriam, MD, Rigamonti, Paolo, MD, Rocco, Elena Guerini, MD, Bosari, Silvano, MD, Ceretti, Andrea Pisani, MD, Soldi, Simone, MD, Peri, Mauro, MD, Sardanelli, Francesco, MD, Cornalba, Gian Paolo, MD

“…Rationale and Objectives To predict the T stage of nonrectal colon cancer using contrast-enhanced computed tomography colonography. Materials and Methods…”
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E‐cadherin deregulation in breast cancer by Corso, Giovanni, Figueiredo, Joana, De Angelis, Simone Pietro, Corso, Federica, Girardi, Antonia, Pereira, Joana, Seruca, Raquel, Bonanni, Bernardo, Carneiro, Patricia, Pravettoni, Gabriella, Guerini Rocco, Elena, Veronesi, Paolo, Montagna, Giacomo, Sacchini, Virgilio, Gandini, Sara

“…E‐cadherin protein (CDH1 gene) integrity is fundamental to the process of epithelial polarization and differentiation. Deregulation of the E‐cadherin function…”
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PTEN Alterations and Their Role in Cancer Management: Are We Making Headway on Precision Medicine? by Fusco, Nicola, Sajjadi, Elham, Venetis, Konstantinos, Gaudioso, Gabriella, Lopez, Gianluca, Corti, Chiara, Rocco, Elena Guerini, Criscitiello, Carmen, Malapelle, Umberto, Invernizzi, Marco

“…Alterations in the tumor suppressor phosphatase and tensin homolog ( ) occur in a substantial proportion of solid tumors. These events drive tumorigenesis and…”
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HER2 Low, Ultra-low, and Novel Complementary Biomarkers: Expanding the Spectrum of HER2 Positivity in Breast Cancer by Venetis, Konstantinos, Crimini, Edoardo, Sajjadi, Elham, Corti, Chiara, Guerini-Rocco, Elena, Viale, Giuseppe, Curigliano, Giuseppe, Criscitiello, Carmen, Fusco, Nicola

“…HER2 status in breast cancer is assessed to select patients eligible for targeted therapy with anti-HER2 therapies. According to the American Society of…”
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Clinical actionability of BRCA2 alterations in uterine leiomyosarcoma: a molecular tumor board case report and a cBioPortal comprehensive analysis by Boscolo Bielo, Luca, Repetto, Matteo, Crimini, Edoardo, Belli, Carmen, Setola, Elisabetta, Parma, Gabriella, Fusco, Nicola, Barberis, Massimo, Guerini Rocco, Elena, Marra, Antonio, Colombo, Nicoletta, Curigliano, Giuseppe

“…Uterine leiomyosarcoma (uLMS) represents one of the most common sarcoma histotypes, demonstrating an overall dismal prognosis. Previous studies reported uLMS…”
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Lobular Carcinoma in Situ: A 29-Year Longitudinal Experience Evaluating Clinicopathologic Features and Breast Cancer Risk by King, Tari A, Pilewskie, Melissa, Muhsen, Shirin, Patil, Sujata, Mautner, Starr K, Park, Anna, Oskar, Sabine, Guerini-Rocco, Elena, Boafo, Camilla, Gooch, Jessica C, De Brot, Marina, Reis-Filho, Jorge S, Morrogh, Mary, Andrade, Victor P, Sakr, Rita A, Morrow, Monica

“…The increased breast cancer risk conferred by a diagnosis of lobular carcinoma in situ (LCIS) is poorly understood. Here, we review our 29-year longitudinal…”
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