Search Results - "Guerda Duclair"
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Association of Elevated Amyloid and Tau Positron Emission Tomography Signal With Near-Term Development of Alzheimer Disease Symptoms in Older Adults Without Cognitive Impairment
Published in JAMA neurology (01-10-2022)“…National Institute on Aging-Alzheimer's Association (NIA-AA) workgroups have proposed biological research criteria intended to identify individuals with…”
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Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer’s Disease
Published in Biological psychiatry (1969) (15-04-2021)“…Major prevention trials for Alzheimer’s disease (AD) are now focusing on multidomain lifestyle interventions. However, the exact combination of behavioral…”
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Neurobehavioral Mechanisms Influencing the Association Between Generativity, the Desire to Promote Well-Being of Younger Generations, and Purpose in Life in Older Adults at Risk for Alzheimer's Disease
Published in The journals of gerontology. Series B, Psychological sciences and social sciences (01-06-2024)“…Generativity, the desire and action to improve the well-being of younger generations, is associated with purpose in life among older adults. However, the…”
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Resting-state MRI functional connectivity as a neural correlate of multidomain lifestyle adherence in older adults at risk for Alzheimer’s disease
Published in Scientific reports (09-05-2023)“…Prior research has demonstrated the importance of a healthy lifestyle to protect brain health and diminish dementia risk in later life. While a multidomain…”
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Proximity to Parental Symptom Onset and Amyloid-β Burden in Sporadic Alzheimer Disease
Published in JAMA neurology (01-05-2018)“…Alzheimer disease (AD) develops during several decades. Presymptomatic individuals might be the best candidates for clinical trials, but their identification…”
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The neurophysiological brain-fingerprint of Parkinson’s disease
Published in EBioMedicine (01-07-2024)“…Research in healthy young adults shows that characteristic patterns of brain activity define individual “brain-fingerprints” that are unique to each person…”
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Association of Vascular Risk Factors With β-Amyloid Peptide and Tau Burdens in Cognitively Unimpaired Individuals and Its Interaction With Vascular Medication Use
Published in JAMA network open (05-02-2020)“…Vascular risk factors are associated with increased risk of Alzheimer disease (AD), but it is unclear whether there is a direct association of these risk…”
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Subjective Cognitive Decline Is Associated With Altered Default Mode Network Connectivity in Individuals With a Family History of Alzheimer’s Disease
Published in Biological psychiatry : cognitive neuroscience and neuroimaging (01-05-2018)“…Both subjective cognitive decline (SCD) and a family history of Alzheimer’s disease (AD) portend risk of brain abnormalities and progression to dementia…”
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The neurophysiological brain-fingerprint of Parkinson’s diseaseResearch in context
Published in EBioMedicine (01-07-2024)“…Background: Research in healthy young adults shows that characteristic patterns of brain activity define individual “brain-fingerprints” that are unique to…”
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Assessment of white matter hyperintensity severity using multimodal magnetic resonance imaging
Published in Brain communications (01-11-2023)“…Abstract White matter hyperintensities are radiological abnormalities reflecting cerebrovascular dysfunction detectable using MRI. White matter…”
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Test-retest resting-state fMRI in healthy elderly persons with a family history of Alzheimer’s disease
Published in Scientific data (13-10-2015)“…We present a test-retest dataset of resting-state fMRI data obtained in 80 cognitively normal elderly volunteers enrolled in the “Pre-symptomatic Evaluation of…”
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