Search Results - "Guentsch, Annemarie"

Mucosal inflammation downregulates PHD1 expression promoting a barrier‐protective HIF‐1α response in ulcerative colitis patients by Brown, Eric, Rowan, Catherine, Strowitzki, Moritz J., Fagundes, Raphael R., Faber, Klaas Nico, Güntsch, Annemarie, Halligan, Doug N., Kugler, Julia, Jones, Fiona, Lee, Chee T., Doherty, Glen, Taylor, Cormac T.

“…The HIF hydroxylase enzymes (PHD1‐3 and FIH) are cellular oxygen‐sensors which confer hypoxic‐sensitivity upon the hypoxia‐inducible factors HIF‐1α and HIF‐2α…”
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Su1772 – Inflammation-Dependent Transcriptional Re-Programming of the Hif Pathway in the Mucosa of Ulcerative Colitis Patients by Brown, Eric, Rowan, Catherine, Strowitzki, Moritz, Rosa, Raphael Fagundes, Guentsch, Annemarie, Halligan, Doug N., Doherty, Glen, Taylor, Cormac

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Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma by Koch, Raphael, Demant, Martin, Aung, Thiha, Diering, Nina, Cicholas, Anna, Chapuy, Bjoern, Wenzel, Dirk, Lahmann, Marlen, Güntsch, Annemarie, Kiecke, Christina, Becker, Sabrina, Hupfeld, Timo, Venkataramani, Vivek, Ziepert, Marita, Opitz, Lennart, Klapper, Wolfram, Trümper, Lorenz, Wulf, Gerald G.

“…Tumors are composed of phenotypically heterogeneous cell populations. The nongenomic mechanisms underlying transitions and interactions between cell…”
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Loss of PHD3 in myeloid cells dampens the inflammatory response and fibrosis after hind-limb ischemia by Beneke, Angelika, Guentsch, Annemarie, Hillemann, Annette, Zieseniss, Anke, Swain, Lija, Katschinski, Dörthe M

“…Macrophages are essential for the inflammatory response after an ischemic insult and thereby influence tissue recovery. For the oxygen sensing…”
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Redox Imaging Using Cardiac Myocyte-Specific Transgenic Biosensor Mice by Swain, Lija, Kesemeyer, Andrea, Meyer-Roxlau, Stefanie, Vettel, Christiane, Zieseniss, Anke, Güntsch, Annemarie, Jatho, Aline, Becker, Andreas, Nanadikar, Maithily S, Morgan, Bruce, Dennerlein, Sven, Shah, Ajay M, El-Armouche, Ali, Nikolaev, Viacheslav O, Katschinski, Dörthe M

“…RATIONALE:Changes in redox potentials of cardiac myocytes are linked to several cardiovascular diseases. Redox alterations are currently mostly described…”
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PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages by Guentsch, Annemarie, Beneke, Angelika, Swain, Lija, Farhat, Katja, Nagarajan, Shunmugam, Wielockx, Ben, Raithatha, Kaamini, Dudek, Jan, Rehling, Peter, Zieseniss, Anke, Jatho, Aline, Chong, Mei, Santos, Celio X. C., Shah, Ajay M., Katschinski, Dörthe M.

“…The prolyl-4-hydroxylase domain (PHD) enzymes are regarded as the molecular oxygen sensors. There is an interplay between oxygen availability and cellular…”
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Exosome Mediated Wnt-Signaling Augments Side Population In Aggressive Lymphoma by Koch, Raphael, Demant, Martin, Aung, Thiha, Guentsch, Annemarie, Diering, Nina, Chapuy, Bjoern, Truemper, Lorenz, Wulf, Gerald

“…Patients with aggressive B-cell lymphoma are treated in curative intention. However, some patients experience fatal relapse, originating from refractory…”
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